Nano-ITX is a computer motherboard form factor first proposed by VIA Technologies at CeBIT in March 2003,^[1][2] and implemented in late 2005. Nano-ITX boards measure 12 × 12 cm (4.7 × 4.7 in), and are fully integrated, very low power consumption motherboards with many uses, but targeted at smart digital entertainment devices such as DVRs, set-top boxes, media centers, car PCs, and thin devices. Nano-ITX motherboards have slots for SO-DIMM.

There are four Nano-ITX motherboard product lines so far, VIA's EPIA N, EPIA NL, EPIA NX, and the VIA EPIA NR. These boards are available from a wide variety of manufacturers supporting numerous different CPU platforms.

Udoo has now released at least 1 nano-ITX board: the Udoo Bolt.