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((short description|Indian-born American chemist (1920–2014)))
((more citations needed|date=May 2014))
((Infobox scientist
|name              = Nariman Bomanshaw Mehta
|image             = Nariman_Mehta.jpg
|image_size        = 
|caption           = Mehta in 2008
|birth_date        = ((Birth date|1920|04|20))
|birth_place       = [[Bombay]], [[Bombay Presidency]], [[British India]]
|death_date        = ((Death date and age|2014|08|22|1920|04|20))<ref name="times-news-obituary">((cite web|url=http://www.legacy.com/obituaries/thetimesnews/obituary.aspx?n=nariman-bomanshaw-mehta&pid=172227930&fhid=16899|title=Nariman Bomanshaw Mehta: Obituary|date=August 23, 2014|work  =Times-News |location=Burlington, North Carolina |access-date=November 20, 2014))</ref>
|death_place       = [[Burlington, North Carolina]], U.S.
|nationality       = American
|field             = [[Organic chemistry]]
|work_institutions = [[Seagram]], [[GlaxoSmithKline]]
|alma_mater        = [[St. Xavier's College, Mumbai]], [[University of Kansas]]
|doctoral_advisor  = 
|doctoral_students = 
|known_for         = Synthesis of antidepressant drug [[Bupropion]] (marketed as [[Wellbutrin]])
|author_abbrev_bot = 
|author_abbrev_zoo = 
|influences        = 
|influenced        = 
|prizes            = 
|religion          = 
|footnotes         = 
|signature         = 
|spouse            = Barbara DeShane
|children          = 2 daughters, 1 son
))

'''Nariman Bomanshaw Mehta''' (April 20, 1920 – August 22, 2014)<ref name="times-news-obituary" /> was an [[Indian American|Indian-born American]] [[organic chemist]] and [[pharmacologist]] who designed, synthesized, and patented the organic compound [[bupropion]], marketed under the name [[Wellbutrin]] as an [[antidepressant]] and [[smoking cessation]] aid.<ref>((US patent|3819706))</ref>

==Early life and education==
Mehta was born in [[Bombay]], India into a [[Parsi]] [[Zoroastrian]] family. He attended [[St. Xavier's College, Mumbai|St. Xavier's College]] in [[Bombay]], from where he received [[Bachelor of Science]] degrees in [[chemistry]] and [[physics]] and  [[Bachelor of Arts]] degrees in [[English studies|English]] and [[economics]], and a [[Master of Science]] degree. In 1939, he and fellow student [[Kaikhosrov D. Irani]], later a noted academic in his own right, wrote and published a Textbook ''of Theoretical and Practical Physics''.<ref>[http://www.kdirani.com/books.htm Irani K.D. and Mehta N.B.] (1942) "Theoretical and Practical Physics"</ref>

Mehta won a Tata Scholarship and received a grant from [[Wendell Willkie]]. In 1947 Mehta went to the United States, where he earned a PhD in chemistry from [[The University of Kansas]].((Citation needed|date=October 2021)) Mehta's 1952 dissertation was titled ''I. Use of the Hammett equation in the prediction of product ratios in the Schmidt reaction of unsymmetrical diarylethylenes: II. The synthesis of possible emetine intermediates''.<ref>((Cite thesis|title=I. Use of the Hammett equation in the prediction of product ratios in the Schmidt reaction of unsymmetrical diarylethylenes: II. The synthesis of possible emetine intermediates|date=1952|language=English|first=Nariman Bomanshaw|last=Mehta|degree=Ph.D.|publisher=University of Kansas|oclc=55019928))</ref>

He had two daughters and a son.((cn|date=May 2023))

==Career==
[[Seagram]] invited Mehta to the United States as a trainee in their research lab, where he learned about [[fermentation]] and [[distillation]]. During his time at Seagram, Mehta studied the antibiotic [[Penicillin]]. While teaching chemistry at [[Central State University]], [[Wilberforce, Ohio]], Mehta joined the pharmaceutical company Burroughs Wellcome, Inc., now [[GlaxoSmithKline]], where he worked on potential [[neuropsychopharmacology|neuropsychopharmacological drugs]] and designed, synthesized, and patented (in 1969) the compound [[Bupropion]] (BW 323U66) that was approved for use as an [[antidepressant]] in 1985 and sold under the trade name Wellbutrin. Another application of the drug was as a [[smoking cessation]] aid.<ref>((cite web|url=http://historyofmentalhealth.com/2014/01/10/dec-30-1985-want-a-zyban/ |title=1985: Want a Zyban? |publisher=The history of mental health |first=Henk |last=van Setten|access-date=29 November 2014))</ref>

==Selected publications==
* ((Citation
|pmid =6406464
|last= Mehta
|first= N B
|publication-date= May 1983
|year= 1983
|title= The Chemistry of Bupropion
|volume= 44
|issue= 5
|periodical= The Journal of Clinical Psychiatry
|pages= 56–9
))
* ((Citation
|doi= 10.1002/chir.530050704
|publication-date= 2004-09-21
|year= 2004
|title= Synthesis and evaluation of the antidepressant activity of the enantiomers of bupropion
|volume= 5
|issue= 7
|pages= 495–500
|author1=David L. Musso |author2=Nariman B. Mehta |author3=Francis E. Soroko |author4=Robert M. Ferris |author5=Elizabeth B. Hollingsworth |author6=Bernard T. Kenney |pmid= 8240925
|journal= Chirality
))
* ((Citation|last=Mehta|first=Nariman B |author2=Arthur P Phillips |author3=Florence Fu Lui |author4=Ronald E Brooks |title=Maleamic and citraconamic acids, methyl esters, and imides|journal=The Journal of Organic Chemistry|year=1960|volume=25|issue=6|pages=1012–1015|doi=10.1021/jo01076a038))

==Notes==
((Reflist))

===References===
* ((cite web |url=https://sites.google.com/site/narimanbmehta/ |title=Dr. Nariman B. Mehta: A scientist and a chemist |author=<!--Staff writer(s); no by-line.--> |access-date=May 24, 2014))
* ((cite book |last1=Schatzberg |first1=Alan F. |last2=Nemeroff | first2=Charles B. |year=2009 |title=The American Psychiatric Publishing Textbook of Psychopharmacology |edition=4 |publisher=American Psychiatric Publishing, Inc. |page=416 |isbn=978-1585623099 ))
* ((cite journal |last=Wilson |first=Brent |last2=Paul |first2=Panchajanya |last3=Mehta |first3=Sunny |last4=Coffey |first4=Barbara |date=February 2013 |title=Hypokalemia Secondary to Bupropion Sustained Release Overdose|journal=Journal of Child and Adolescent Psychopharmacology |volume=23 |issue=1 |pages=57–60 |doi= 10.1089/cap.2013.2313|pmc=3613169 |pmid=23410142))

((authority control))

((DEFAULTSORT:Mehta, Nariman))
[[Category:1920 births]]
[[Category:2014 deaths]]
[[Category:20th-century Indian inventors]]
[[Category:Indian pharmacologists]]
[[Category:Indian emigrants to the United States]]
[[Category:Indian biochemists]]
[[Category:GSK plc]]
[[Category:St. Xavier's College, Mumbai alumni]]
[[Category:University of Kansas alumni]]
[[Category:20th-century Indian chemists]]
[[Category:Scientists from Mumbai]]
[[Category:American people of Parsi descent]]
[[Category:Parsi people from Mumbai]]
[[Category:Parsi people]]

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