This is a list of items on the National Register of Historic Places listings in Darlington County, South Carolina.

This is intended to be a complete list of the properties and districts on the National Register of Historic Places in Darlington County, South Carolina, United States. The locations of National Register properties and districts for which the latitude and longitude coordinates are included below, may be seen in a map.^[1]

There are 52 properties and districts listed on the National Register in the county, including one National Historic Landmark.

          This National Park Service list is complete through NPS recent listings posted February 23, 2024.^[2]

Current listings

[3]	Name on the Register[4]	Image	Date listed[5]	Location	City or town	Description
1	Arcade Hotel		December 19, 1986 (#86003467)	204 N. 5th St. 34°22′30″N 80°04′28″W / 34.375°N 80.074444°W / 34.375; -80.074444 (Arcade Hotel)	Hartsville
2	W.E. Cannon House and Store		May 3, 1991 (#91000470)	612 W. Home Ave. 34°22′19″N 80°05′18″W / 34.371944°N 80.088333°W / 34.371944; -80.088333 (W.E. Cannon House and Store)	Hartsville
3	Cashua Street-Spring Street Historic District	More images	February 10, 1988 (#88000064)	Cashua St. between Columbian St. and Warley St., and Spring St. between Cashua St. and N. Ervin St. 34°18′25″N 79°52′01″W / 34.306944°N 79.866944°W / 34.306944; -79.866944 (Cashua Street-Spring Street Historic District)	Darlington
4	Coker Experimental Farms		October 15, 1966 (#66000706)	West of Hartsville on South Carolina Highway 151 34°21′47″N 80°03′35″W / 34.363056°N 80.059722°W / 34.363056; -80.059722 (Coker Experimental Farms)	Hartsville	National Historic Landmark
5	J.L. Coker Company Building		February 9, 1983 (#83002192)	5th St. and Carolina Ave. 34°22′27″N 80°04′22″W / 34.374167°N 80.072778°W / 34.374167; -80.072778 (J.L. Coker Company Building)	Hartsville
6	James L. Coker III House	Upload image	May 3, 1991 (#91000471)	620 W. Home Ave. 34°22′18″N 80°05′20″W / 34.371667°N 80.088889°W / 34.371667; -80.088889 (James L. Coker III House)	Hartsville
7	Robert R. Coker House		September 8, 1994 (#94001130)	1318 W. Carolina Ave. 34°22′01″N 80°06′22″W / 34.36686°N 80.10611°W / 34.36686; -80.10611 (Robert R. Coker House)	Hartsville
8	S. Pressly Coker House	Upload image	September 8, 1994 (#94001131)	402 W. Home Ave. 34°22′16″N 80°04′52″W / 34.371111°N 80.081111°W / 34.371111; -80.081111 (S. Pressly Coker House)	Hartsville
9	Julius A. Dargan House		February 10, 1988 (#88000036)	488 Pearl St. 34°18′00″N 79°52′38″W / 34.29997°N 79.87722°W / 34.29997; -79.87722 (Julius A. Dargan House)	Darlington
10	Darlington Downtown Historic District	More images	July 5, 2006 (#06000546)	Along portions of S. Main St., Pearl St., Public Sq., and Exchange St. 34°18′10″N 79°52′17″W / 34.302778°N 79.871389°W / 34.302778; -79.871389 (Darlington Downtown Historic District)	Darlington
11	Darlington Industrial Historic District	Upload image	February 10, 1988 (#88000062)	Roughly bounded by 6th St., Ave. B, Dargan St., and Siskron St. 34°18′01″N 79°51′54″W / 34.300278°N 79.865°W / 34.300278; -79.865 (Darlington Industrial Historic District)	Darlington
12	Darlington Memorial Cemetery	Upload image	June 9, 2005 (#05000576)	Ave. D and Friendship St. 34°17′34″N 79°51′22″W / 34.292778°N 79.856111°W / 34.292778; -79.856111 (Darlington Memorial Cemetery)	Darlington
13	Davidson Hall, Coker College		November 10, 1983 (#83003835)	College Ave. 34°22′38″N 80°04′05″W / 34.377222°N 80.068056°W / 34.377222; -80.068056 (Davidson Hall, Coker College)	Hartsville
14	Edmund H. Deas House		February 10, 1988 (#88000045)	229 Ave. E 34°17′44″N 79°51′46″W / 34.29559°N 79.86265°W / 34.29559; -79.86265 (Edmund H. Deas House)	Darlington
15	Dove Dale	Upload image	February 22, 2007 (#07000075)	Address Restricted	Darlington
16	C.K. Dunlap House	Upload image	May 3, 1991 (#91000472)	1346 W. Carolina Ave. 34°22′32″N 80°06′30″W / 34.375556°N 80.108333°W / 34.375556; -80.108333 (C.K. Dunlap House)	Hartsville
17	East Home Avenue Historic District	More images	May 3, 1991 (#91000475)	Roughly E. Home Ave. from N. 5th St. to just east of 1st Ave. 34°22′45″N 80°04′14″W / 34.379167°N 80.070556°W / 34.379167; -80.070556 (East Home Avenue Historic District)	Hartsville
18	First Baptist Church		October 17, 1991 (#88000061)	246 S. Main St. 34°17′59″N 79°52′12″W / 34.299722°N 79.87°W / 34.299722; -79.87 (First Baptist Church)	Darlington
19	J.B. Gilbert House		May 3, 1991 (#91000473)	200 Fairfield Terrace 34°22′48″N 80°04′26″W / 34.38°N 80.073889°W / 34.38; -80.073889 (J.B. Gilbert House)	Hartsville
20	Arthur Goodson House	Upload image	October 10, 1985 (#85003137)	West of County Road 133 34°20′42″N 79°51′14″W / 34.345°N 79.853889°W / 34.345; -79.853889 (Arthur Goodson House)	Springville
21	John L. Hart House		November 10, 1983 (#83003843)	Home Ave. 34°22′36″N 80°04′26″W / 34.376667°N 80.073889°W / 34.376667; -80.073889 (John L. Hart House)	Hartsville
22	John L. Hart House	Upload image	October 10, 1985 (#85003138)	East of County Road 133 34°20′42″N 79°51′07″W / 34.345°N 79.851944°W / 34.345; -79.851944 (John L. Hart House)	Springville
23	Thomas E. Hart House		May 3, 1991 (#91000474)	624 W. Carolina Ave. 34°22′01″N 80°06′57″W / 34.366944°N 80.115833°W / 34.366944; -80.115833 (Thomas E. Hart House)	Hartsville
24	Hartsville Armory	More images	September 8, 1994 (#94001128)	539 W. Carolina Ave. 34°22′09″N 80°05′06″W / 34.369167°N 80.085°W / 34.369167; -80.085 (Hartsville Armory)	Hartsville
25	Hartsville Community Center-Hartsville Community Market		June 4, 1997 (#97000538)	5th St. between College and Home Ave., and 106 W. College Ave. 34°22′32″N 80°04′28″W / 34.375556°N 80.074444°W / 34.375556; -80.074444 (Hartsville Community Center-Hartsville Community Market)	Hartsville
26	Hartsville Passenger Station	More images	June 29, 1976 (#76001700)	114 S. 4th St. 34°22′24″N 80°04′26″W / 34.373333°N 80.073889°W / 34.373333; -80.073889 (Hartsville Passenger Station)	Hartsville
27	Hartsville Post Office		June 4, 1997 (#97000537)	Junction of Home Ave. and 5th St. 34°22′33″N 80°04′29″W / 34.375833°N 80.074722°W / 34.375833; -80.074722 (Hartsville Post Office)	Hartsville
28	Wade Hampton Hicks House		September 8, 1994 (#94001127)	313 W. Home Ave. 34°22′26″N 80°04′47″W / 34.373889°N 80.079722°W / 34.373889; -80.079722 (Wade Hampton Hicks House)	Hartsville
29	Nelson Hudson House	Upload image	February 10, 1988 (#88000039)	521 Pearl St.** 34°17′56″N 79°52′40″W / 34.298889°N 79.877778°W / 34.298889; -79.877778 (Nelson Hudson House)	Darlington	**house since moved from original location to unknown site
30	Japonica Hall	Upload image	December 21, 1989 (#89002153)	S. Main St. 34°30′21″N 79°51′35″W / 34.505833°N 79.859722°W / 34.505833; -79.859722 (Japonica Hall)	Society Hill
31	Jacob Kelley House	Upload image	May 6, 1971 (#71000768)	West of Hartsville on S-16-12 34°20′59″N 80°08′45″W / 34.349722°N 80.145833°W / 34.349722; -80.145833 (Jacob Kelley House)	Hartsville
32	Lawton Park and Pavilion		May 3, 1991 (#91000476)	Prestwood Dr. at its junction with Lanier Dr. 34°22′55″N 80°04′48″W / 34.381944°N 80.08°W / 34.381944; -80.08 (Lawton Park and Pavilion)	Hartsville
33	Evan J. Lide House	Upload image	October 10, 1985 (#85003139)	West of County Road 228 northwest of South Carolina Highway 34 34°19′46″N 79°50′57″W / 34.329444°N 79.849167°W / 34.329444; -79.849167 (Evan J. Lide House)	Springville
34	John W. Lide House	Upload image	October 10, 1985 (#85003140)	West of County Road 133 34°21′09″N 79°51′34″W / 34.3525°N 79.859444°W / 34.3525; -79.859444 (John W. Lide House)	Springville
35	Lydia Plantation		May 28, 2010 (#10000299)	703 W Lydia Hwy (US HWY 15/SC HWY 34) 34°17′28″N 80°06′18″W / 34.291078°N 80.104894°W / 34.291078; -80.104894 (Lydia Plantation)	Lydia
36	Magnolia Cemetery	More images	September 8, 1994 (#94001133)	S. Cedar Ln. 34°21′52″N 80°05′28″W / 34.364444°N 80.091111°W / 34.364444; -80.091111 (Magnolia Cemetery)	Hartsville
37	Manne Building		February 10, 1988 (#88000044)	129 Pearl St. 34°18′08″N 79°52′18″W / 34.302222°N 79.871667°W / 34.302222; -79.871667 (Manne Building)	Darlington
38	Clarence McCall House		February 10, 1988 (#88000058)	870 Cashua St. 34°18′35″N 79°51′46″W / 34.30980°N 79.86283°W / 34.30980; -79.86283 (Clarence McCall House)	Darlington
39	Charles S. McCullough House		February 10, 1988 (#88000060)	480 Pearl St. 34°18′01″N 79°52′36″W / 34.3003°N 79.8767°W / 34.3003; -79.8767 (Charles S. McCullough House)	Darlington
40	A.M. McNair House		September 8, 1994 (#94001126)	153 W. Home Ave. 34°22′31″N 80°04′35″W / 34.375278°N 80.076389°W / 34.375278; -80.076389 (A.M. McNair House)	Hartsville
41	Memorial Hall		February 9, 1989 (#89000001)	2nd St. between Home Ave. and Carolina Ave. 34°22′42″N 80°04′01″W / 34.378333°N 80.066944°W / 34.378333; -80.066944 (Memorial Hall)	Hartsville
42	Oaklyn Plantation	Upload image	February 2, 1995 (#94001630)	Junction of S. Charleston Rd. (South Carolina Highway 35) and Pocket Rd. (South Carolina Highway 173) 34°16′46″N 79°46′52″W / 34.279444°N 79.781111°W / 34.279444; -79.781111 (Oaklyn Plantation)	Darlington
43	Paul H. Rogers House		September 8, 1994 (#94001125)	628 W. Home Ave. 34°22′17″N 80°05′22″W / 34.371389°N 80.089444°W / 34.371389; -80.089444 (Paul H. Rogers House)	Hartsville
44	St. John's Historic District	Upload image	September 4, 1980 (#80003668)	Park, St. John's, Sanders, and Orange Sts. 34°18′15″N 79°52′32″W / 34.304167°N 79.875556°W / 34.304167; -79.875556 (St. John's Historic District)	Darlington
45	South Carolina Western Railway Station		February 10, 1988 (#88000040)	129 Russell St. 34°18′13″N 79°52′08″W / 34.303611°N 79.868889°W / 34.303611; -79.868889 (South Carolina Western Railway Station)	Darlington
46	Welsh Neck-Long Bluff-Society Hill Historic District	Upload image	December 16, 1974 (#74001846)	Southwest of Bennettsville along U.S. Route 15 34°31′35″N 79°49′39″W / 34.526389°N 79.8275°W / 34.526389; -79.8275 (Welsh Neck-Long Bluff-Society Hill Historic District)	Bennettsville
47	West Broad Street Historic District	Upload image	February 10, 1988 (#88000063)	W. Broad St. between Dargan St. and Player St. 34°17′49″N 79°52′26″W / 34.296944°N 79.873889°W / 34.296944; -79.873889 (West Broad Street Historic District)	Darlington
48	West College Avenue Historic District	Upload image	September 8, 1994 (#94001123)	W. College Ave. from 6th Ave. to west of 8th Ave. 34°22′24″N 80°04′43″W / 34.373333°N 80.078611°W / 34.373333; -80.078611 (West College Avenue Historic District)	Hartsville
49	White Plains	Upload image	October 10, 1985 (#85003141)	North of County Road 177 and northeast of County Road 389 34°21′24″N 79°53′00″W / 34.356667°N 79.883333°W / 34.356667; -79.883333 (White Plains)	Springville
50	Wilds Hall	Upload image	October 10, 1985 (#85003142)	West of County Road 228 off South Carolina Highway 34 34°19′05″N 79°50′33″W / 34.318056°N 79.8425°W / 34.318056; -79.8425 (Wilds Hall)	Springville
51	Wilds-Edwards House		February 10, 1988 (#88000034)	120 Edwards Ave. 34°17′54″N 79°52′33″W / 34.298333°N 79.875833°W / 34.298333; -79.875833 (Wilds-Edwards House)	Darlington
52	Mrs. B.F. Williamson House		February 10, 1988 (#88000059)	141 Oak St. 34°18′24″N 79°52′17″W / 34.306667°N 79.871389°W / 34.306667; -79.871389 (Mrs. B.F. Williamson House)	Darlington