This is a list of the National Register of Historic Places listings in Guernsey County, Ohio.

This is intended to be a complete list of the properties and districts on the National Register of Historic Places in Guernsey County, Ohio, United States. The locations of National Register properties and districts for which the latitude and longitude coordinates are included below, may be seen in an online map.^[1]

There are 22 properties and districts listed on the National Register in the county, including 1 National Historic Landmark.

          This National Park Service list is complete through NPS recent listings posted March 1, 2024.^[2]

Current listings

[3]	Name on the Register[4]	Image	Date listed[5]	Location	City or town	Description
1	Barnett-Criss House	More images	December 8, 1978 (#78002070)	Southwest of Cambridge off U.S. Route 22 39°59′59″N 81°41′33″W / 39.999722°N 81.6925°W / 39.999722; -81.6925 (Barnett-Criss House)	Westland Township
2	Berwick Hotel		March 29, 1983 (#83001975)	600-615 Wheeling Ave. 40°01′30″N 81°35′36″W / 40.025°N 81.593333°W / 40.025; -81.593333 (Berwick Hotel)	Cambridge
3	Bethel Methodist Episcopal Church		November 24, 1978 (#78002072)	West of Pleasant City on State Route 146 39°54′04″N 81°35′01″W / 39.901111°N 81.583611°W / 39.901111; -81.583611 (Bethel Methodist Episcopal Church)	Valley Township
4	Booth Homestead		September 6, 1979 (#79001851)	North of Guernsey at 8433 Township Road 838 40°12′23″N 81°34′37″W / 40.206389°N 81.576944°W / 40.206389; -81.576944 (Booth Homestead)	Wheeling Township
5	Broom Building		February 17, 1983 (#83001976)	701 Wheeling Ave. 40°01′30″N 81°35′31″W / 40.025°N 81.591944°W / 40.025; -81.591944 (Broom Building)	Cambridge
6	Broom-Braden Stone House		July 18, 1980 (#80003032)	North of Cambridge at 66715 Reed Rd. 40°04′12″N 81°33′31″W / 40.07°N 81.558611°W / 40.07; -81.558611 (Broom-Braden Stone House)	Cambridge Township
7	Claysville School	More images	February 22, 1979 (#79001850)	North of Claysville on Claysville Rd. 39°56′18″N 81°40′16″W / 39.938333°N 81.671111°W / 39.938333; -81.671111 (Claysville School)	Westland Township
8	Ebenezer Finley House		February 28, 1986 (#86000417)	East of Buffalo on State Route 313 39°55′28″N 81°29′37″W / 39.924444°N 81.493611°W / 39.924444; -81.493611 (Ebenezer Finley House)	Valley Township	Destroyed
9	Guernsey County Courthouse	More images	July 16, 1973 (#73001452)	Courthouse Sq. 40°01′30″N 81°35′14″W / 40.025°N 81.587222°W / 40.025; -81.587222 (Guernsey County Courthouse)	Cambridge
10	Samuel Harper Stone House		January 3, 1980 (#80003033)	North of New Concord on Peters Creek Rd. 40°02′00″N 81°43′12″W / 40.033333°N 81.72°W / 40.033333; -81.72 (Samuel Harper Stone House)	Adams Township
11	Kennedy Stone House		October 3, 1975 (#75001412)	Southeast of North Salem in Salt Fork State Park 40°07′41″N 81°29′59″W / 40.128056°N 81.499722°W / 40.128056; -81.499722 (Kennedy Stone House)	Jefferson Township
12	McCracken-McFarland House	More images	February 16, 1979 (#79001848)	216 N. 8th St. 40°01′36″N 81°35′24″W / 40.026667°N 81.59°W / 40.026667; -81.59 (McCracken-McFarland House)	Cambridge
13	McCracken-Scott House		December 20, 1978 (#78002071)	819 Steubenville Ave. 40°01′35″N 81°35′22″W / 40.026389°N 81.589444°W / 40.026389; -81.589444 (McCracken-Scott House)	Cambridge
14	McCreary-Burnworth House		March 12, 1982 (#82003574)	220 Highland Ave. 40°01′34″N 81°34′53″W / 40.026111°N 81.581389°W / 40.026111; -81.581389 (McCreary-Burnworth House)	Cambridge
15	National Road		August 23, 1985 (#85001842)	Township Road 650, east of Cambridge 40°01′37″N 81°30′09″W / 40.026944°N 81.5025°W / 40.026944; -81.5025 (National Road)	Center Township
16	Old Washington Historic District		May 29, 1975 (#75001413)	Both sides of Main St. 40°02′18″N 81°26′35″W / 40.038333°N 81.443056°W / 40.038333; -81.443056 (Old Washington Historic District)	Old Washington
17	S Bridge, National Road	More images	October 15, 1966 (#66000610)	4 mi (6.4 km) east of Old Washington on U.S. Route 40 40°02′43″N 81°22′27″W / 40.045278°N 81.374167°W / 40.045278; -81.374167 (S Bridge, National Road)	Wills Township
18	Peter B. Sarchet House		February 22, 1979 (#79001849)	North of Cambridge on Oldham Rd. 40°05′02″N 81°35′13″W / 40.083889°N 81.586944°W / 40.083889; -81.586944 (Peter B. Sarchet House)	Cambridge Township
19	Sarchet-Burgess House	More images	May 21, 1987 (#87000808)	145 W. 8th St. 40°01′33″N 81°35′26″W / 40.025833°N 81.590556°W / 40.025833; -81.590556 (Sarchet-Burgess House)	Cambridge
20	Matthew Scott House	Upload image	April 17, 2023 (#100008837)	210 Fair Ave. 40°03′23″N 81°13′53″W / 40.0565°N 81.2315°W / 40.0565; -81.2315 (Matthew Scott House)	Fairview
21	Colonel Joseph Taylor House	More images	August 29, 2008 (#08000801)	633 Upland Rd. 40°02′00″N 81°35′33″W / 40.033386°N 81.592367°W / 40.033386; -81.592367 (Colonel Joseph Taylor House)	Cambridge
22	Wheeling Avenue Historic District		May 11, 1987 (#87000919)	Roughly bounded by Steubenville, 10th, Wheeling, and 4th Aves. 40°01′29″N 81°35′27″W / 40.024833°N 81.590969°W / 40.024833; -81.590969 (Wheeling Avenue Historic District)	Cambridge