This is a list of the National Register of Historic Places listings in Jefferson County, Indiana.

This is intended to be a complete list of the properties and districts on the National Register of Historic Places in Jefferson County, Indiana, United States. Latitude and longitude coordinates are provided for many National Register properties and districts; these locations may be seen together in a map.^[1]

There are 13 properties and districts listed on the National Register in the county, including 4 National Historic Landmarks.

Properties and districts located in incorporated areas display the name of the municipality, while properties and districts in unincorporated areas display the name of their civil township. Properties and districts split between multiple jurisdictions display the names of all jurisdictions.

          This National Park Service list is complete through NPS recent listings posted April 12, 2024.^[2]

Current listings

[3]	Name on the Register[4]	Image	Date listed[5]	Location	City or town	Description
1	Lemuel Allen Farm		June 7, 2016 (#16000334)	3768 E. Pleasant Ridge Rd. 38°45′32″N 85°19′04″W / 38.758889°N 85.317778°W / 38.758889; -85.317778 (Lemuel Allen Farm)	Madison Township
2	Crawford-Whitehead-Ross House		November 27, 1992 (#92001648)	510 W. Main St. 38°44′15″N 85°23′06″W / 38.737500°N 85.385000°W / 38.737500; -85.385000 (Crawford-Whitehead-Ross House)	Madison
3	Crowe-Garritt House		November 10, 1980 (#80000041)	172 Crowe St. 38°42′55″N 85°28′16″W / 38.715278°N 85.471111°W / 38.715278; -85.471111 (Crowe-Garritt House)	Hanover
4	Eleutherian College	More images	December 15, 1993 (#93001410)	State Road 250 at Lancaster 38°49′51″N 85°30′59″W / 38.830833°N 85.516389°W / 38.830833; -85.516389 (Eleutherian College)	Lancaster Township
5	Thomas A. Hendricks Library	More images	February 26, 1982 (#82000043)	College Dr. (Campus Rd.) east of Hanover 38°42′45″N 85°27′28″W / 38.7125°N 85.457778°W / 38.7125; -85.457778 (Thomas A. Hendricks Library)	Hanover Township
6	Lyman and Asenath Hoyt House		September 28, 2003 (#03000977)	7147 W. State Road 250 at Lancaster 38°49′56″N 85°31′14″W / 38.832222°N 85.520556°W / 38.832222; -85.520556 (Lyman and Asenath Hoyt House)	Lancaster Township
7	Jefferson County Jail	More images	June 18, 1973 (#73000019)	Courthouse Square 38°44′09″N 85°22′35″W / 38.735833°N 85.376389°W / 38.735833; -85.376389 (Jefferson County Jail)	Madison
8	Lanier Mansion	More images	April 19, 1994 (#94001191)	511 W. 1st St. 38°44′07″N 85°23′10″W / 38.735278°N 85.386111°W / 38.735278; -85.386111 (Lanier Mansion)	Madison
9	Madison Historic District	More images	May 25, 1973 (#73000020)	Roughly bounded by Crooked Creek, Springdale Cemetery, Michigan, New Hill and Telegraph Hill Rds., and the Ohio River 38°44′10″N 85°22′48″W / 38.736111°N 85.380000°W / 38.736111; -85.380000 (Madison Historic District)	Madison
10	Oakdale School	Upload image	May 14, 1993 (#93000432)	Morgan Rd., Jefferson Proving Ground 38°50′24″N 85°25′33″W / 38.84°N 85.425833°W / 38.84; -85.425833 (Oakdale School)	Monroe Township
11	St. Stephen's African Methodist Episcopal Church	More images	December 28, 2000 (#00001544)	220 W. Main St. 38°42′53″N 85°28′38″W / 38.714722°N 85.477222°W / 38.714722; -85.477222 (St. Stephen's African Methodist Episcopal Church)	Hanover
12	Charles L. Shrewsbury House	More images	April 19, 1994 (#94001190)	301 W. 1st St. 38°44′05″N 85°22′58″W / 38.734722°N 85.382778°W / 38.734722; -85.382778 (Charles L. Shrewsbury House)	Madison
13	Mathias Wolf Farm		June 7, 2016 (#16000335)	4137 E. Pleasant Ridge Rd. 38°45′45″N 85°18′38″W / 38.762500°N 85.310694°W / 38.762500; -85.310694 (Mathias Wolf Farm)	Madison Township