This is a list of the National Register of Historic Places listings in Mesa County, Colorado.

This is intended to be a complete list of the properties and districts on the National Register of Historic Places in Mesa County, Colorado, United States. The locations of National Register properties and districts for which the latitude and longitude coordinates are included below, may be seen in a map.^[1]

There are 35 properties and districts listed on the National Register in the county. Another 2 properties were once listed but have been removed.

          This National Park Service list is complete through NPS recent listings posted January 19, 2024.^[2]

Current listings

[3]	Name on the Register[4]	Image	Date listed[5]	Location	City or town	Description
1	Bloomfield Site	Upload image	January 20, 1983 (#83001324)	Address Restricted	Whitewater
2	Calamity Camp	Upload image	June 1, 2011 (#11000313)	Address Restricted	Gateway	Mining Industry in Colorado MPS
3	Cayton Guard Station	Upload image	April 27, 2005 (#05000335)	Forest Service Road 814.1 39°18′20″N 107°33′53″W / 39.305614°N 107.564752°W / 39.305614; -107.564752 (Cayton Guard Station)	Silt	Log cabin built in 1910 to serve National Forest rangers.
4	Clifton Community Center and Church		June 3, 1982 (#82002307)	F and Front St. 39°05′29″N 108°26′57″W / 39.091389°N 108.449167°W / 39.091389; -108.449167 (Clifton Community Center and Church)	Clifton
5	Coates Creek Schoolhouse		February 3, 1993 (#92001839)	D S Rd., 16 miles (26 km) west of Glade Park 38°56′55″N 108°58′35″W / 38.948584°N 108.976400°W / 38.948584; -108.976400 (Coates Creek Schoolhouse)	Glade Park	One-room schoolhouse.
6	Colorado National Monument Visitor Center Complex	More images	July 15, 2003 (#03000647)	Colorado National Monument 39°06′07″N 108°43′50″W / 39.101944°N 108.730556°W / 39.101944; -108.730556 (Colorado National Monument Visitor Center Complex)	Fruita
7	Colorado River Bridge		October 15, 2002 (#02001154)	Interstate 70 frontage road at milepost 62.90 39°20′20″N 108°11′36″W / 39.338889°N 108.193333°W / 39.338889; -108.193333 (Colorado River Bridge)	De Beque
8	Convicts' Bread Oven	More images	December 31, 1974 (#74000589)	West of Molina on State Highway 65 39°12′02″N 108°11′29″W / 39.200556°N 108.191389°W / 39.200556; -108.191389 (Convicts' Bread Oven)	Molina
9	Herbert and Edith Crissey House		May 18, 2003 (#03000402)	218 W. 1st St. 39°06′44″N 108°21′07″W / 39.112222°N 108.351944°W / 39.112222; -108.351944 (Herbert and Edith Crissey House)	Palisade
10	Cross Land and Fruit Company Orchards and Ranch		March 28, 1980 (#80000912)	Northeast of Grand Junction at 3079 F Rd. 39°05′28″N 108°28′52″W / 39.091111°N 108.481111°W / 39.091111; -108.481111 (Cross Land and Fruit Company Orchards and Ranch)	Grand Junction
11	De Beque House		July 28, 1995 (#95000936)	233 Denver Ave. 39°19′49″N 108°13′04″W / 39.330278°N 108.217778°W / 39.330278; -108.217778 (De Beque House)	De Beque
12	Denver and Rio Grande Western Railroad Depot		September 8, 1992 (#92001190)	119 Pitkin Ave. 39°03′51″N 108°34′09″W / 39.064167°N 108.569167°W / 39.064167; -108.569167 (Denver and Rio Grande Western Railroad Depot)	Grand Junction
13	Department of Energy Grand Junction Office		July 26, 2016 (#16000470)	2591 Legacy Way 39°02′31″N 108°34′21″W / 39.042080°N 108.572517°W / 39.042080; -108.572517 (Department of Energy Grand Junction Office)	Grand Junction
14	Devils Kitchen Picnic Shelter	More images	April 21, 1994 (#94000309)	Colorado National Monument 39°01′58″N 108°37′59″W / 39.032778°N 108.633056°W / 39.032778; -108.633056 (Devils Kitchen Picnic Shelter)	Grand Junction
15	Fruita Bridge	More images	February 4, 1985 (#85000218)	17 1/2 Rd over the Colorado River 39°08′13″N 108°43′50″W / 39.136944°N 108.730556°W / 39.136944; -108.730556 (Fruita Bridge)	Fruita
16	Fruita Museum	More images	October 10, 1996 (#96001080)	432 E. Aspen 39°08′59″N 108°43′45″W / 39.149722°N 108.729167°W / 39.149722; -108.729167 (Fruita Museum)	Fruita
17	Grand Valley Diversion Dam	More images	October 8, 1991 (#91001485)	Across the Colorado River north of its confluence with Plateau Creek, 8 miles (13 km) northeast of Palisade 39°11′20″N 108°16′53″W / 39.188889°N 108.281389°W / 39.188889; -108.281389 (Grand Valley Diversion Dam)	Palisade
18	Handy Chapel	More images	August 19, 1994 (#94001012)	202 White Ave. 39°04′10″N 108°34′07″W / 39.069444°N 108.568611°W / 39.069444; -108.568611 (Handy Chapel)	Grand Junction
19	Hotel St. Regis	More images	October 22, 1992 (#92001410)	359 Colorado Ave. 39°03′58″N 108°33′56″W / 39.066111°N 108.565556°W / 39.066111; -108.565556 (Hotel St. Regis)	Grand Junction
20	IOOF Hall	More images	March 25, 1993 (#93000200)	Junction of 4th St. and Curtis Ave. 39°20′00″N 108°12′51″W / 39.333333°N 108.214167°W / 39.333333; -108.214167 (IOOF Hall)	De Beque
21	Kettle-Jens House		May 6, 1983 (#83001325)	498 32 Rd. 39°04′37″N 108°27′31″W / 39.076944°N 108.458611°W / 39.076944; -108.458611 (Kettle-Jens House)	Clifton
22	Land's End Observatory	More images	February 28, 1997 (#97000124)	Land's End Rd., 10 miles (16 km) west of State Highway 65 39°01′30″N 108°13′25″W / 39.025°N 108.223611°W / 39.025; -108.223611 (Land's End Observatory)	Whitewater
23	Loma Community Hall		November 22, 1995 (#95001338)	1341 13 Road 39°11′56″N 108°48′47″W / 39.198889°N 108.813056°W / 39.198889; -108.813056 (Loma Community Hall)	Loma
24	Margery Building		February 24, 1993 (#93000033)	519-527 Main St. 39°04′02″N 108°33′48″W / 39.067222°N 108.563333°W / 39.067222; -108.563333 (Margery Building)	Grand Junction
25	North Seventh Street Historic Residential District	More images	January 5, 1984 (#84000870)	7th St. between Hill and White Aves. 39°04′19″N 108°33′37″W / 39.071944°N 108.560278°W / 39.071944; -108.560278 (North Seventh Street Historic Residential District)	Grand Junction
26	Harry and Lilly Phillips House	More images	November 13, 1997 (#97001419)	798 N. Mesa St. 39°10′21″N 108°43′58″W / 39.1725°N 108.732778°W / 39.1725; -108.732778 (Harry and Lilly Phillips House)	Fruita
27	Pipe Line School		April 29, 1999 (#99000483)	101 16.5 S Rd. 38°59′50″N 108°44′27″W / 38.997222°N 108.740833°W / 38.997222; -108.740833 (Pipe Line School)	Glade Park
28	Rim Rock Drive Historic District	More images	April 21, 1994 (#94000310)	Colorado National Monument 39°03′25″N 108°42′04″W / 39.056944°N 108.701111°W / 39.056944; -108.701111 (Rim Rock Drive Historic District)	Grand Junction
29	Saddlehorn Caretaker's House and Garage	More images	April 21, 1994 (#94000306)	Colorado National Monument 39°06′05″N 108°43′59″W / 39.101389°N 108.733056°W / 39.101389; -108.733056 (Saddlehorn Caretaker's House and Garage)	Grand Junction
30	Saddlehorn Comfort Station	More images	April 21, 1994 (#94000305)	Colorado National Monument 39°06′17″N 108°44′23″W / 39.104722°N 108.739722°W / 39.104722; -108.739722 (Saddlehorn Comfort Station)	Grand Junction
31	Saddlehorn Utility Area Historic District	More images	April 21, 1994 (#94000308)	Colorado National Monument 39°06′05″N 108°44′17″W / 39.101389°N 108.738056°W / 39.101389; -108.738056 (Saddlehorn Utility Area Historic District)	Grand Junction
32	Serpents Trail	More images	April 21, 1994 (#94000307)	Colorado National Monument 39°01′53″N 108°38′11″W / 39.031389°N 108.636389°W / 39.031389; -108.636389 (Serpents Trail)	Grand Junction
33	Stranges Grocery		March 20, 2013 (#13000079)	226 Pitkin Ave. 39°03′53″N 108°34′08″W / 39.064748°N 108.568786°W / 39.064748; -108.568786 (Stranges Grocery)	Grand Junction
34	TBM Avenger Aircraft N53503	Upload image	November 13, 2017 (#100001791)	CAF Rocky Mountain Wing Museum, 780 Heritage Way, Grand Junction Regional Airport 39°07′04″N 108°31′31″W / 39.117778°N 108.525278°W / 39.117778; -108.525278 (TBM Avenger Aircraft N53503)	Grand Junction
35	U.S. Post Office	More images	January 31, 1980 (#80000913)	400 Rood Ave. 39°04′07″N 108°33′55″W / 39.068611°N 108.565278°W / 39.068611; -108.565278 (U.S. Post Office)	Grand Junction

Former listings

[3]	Name on the Register	Image	Date listed	Date removed	Location	City or town	Description
1	Black Bridge	More images	February 4, 1985 (#85000219)	July 22, 1994	25 3/10 Rd over the Gunnison River	Grand Junction	Damaged by flooding in 1983. Demolished in 1988.[6]
2	Fifth Street Bridge		February 4, 1985 (#85000220)	July 22, 1994	Northbound U.S. Highway 50 over the Colorado River	Grand Junction	Replaced in 1989.[6]