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((refimprove|date=April 2009))
((Infobox medical condition (new)
| name            = Necrobiosis
| synonyms        = 
| image           = 
| caption         = 
| pronounce       = 
| field           = [[Pathology]]
| symptoms        = 
| complications   = 
| onset           = 
| duration        = 
| types           = 
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))
'''Necrobiosis''' is the physiological death of a [[cell (biology)|cell]], and can be caused by conditions such as [[basophilia]], [[erythema]], or a [[tumor]].  It is identified both with<ref>[http://www.emedicine.com/asp/dictionary.asp?keyword=Necrobiosis eMedicine/Stedman Medical Dictionary Lookup]</ref> and without [[necrosis]].

Necrobiotic disorders are characterized by presence of necrobiotic granuloma on histopathology. Necrobiotic granuloma is described as aggregation of histiocytes around a central area of altered collagen and elastic fibers. Such a granuloma is typically arranged in a palisaded pattern.<ref>((Cite journal |last1=Pokharel |first1=Achyut |last2=Koirala |first2=Isha Poudel |date=22 May 2018 |title=Necrobiotic granuloma: An update |url=https://www.ijdpdd.com/article.asp?issn=2349-6029;year=2018;volume=5;issue=1;spage=27;epage=33;aulast=Pokharel |journal=Indian Journal of Dermatopathology and Diagnostic Dermatology |volume=5 |issue=1 |pages=27–33 |doi=10.4103/ijdpdd.ijdpdd_12_18|s2cid=81162412 |doi-access=free ))</ref>

It is associated with [[necrobiosis lipoidica]] and [[granuloma annulare]].

Necrobiosis differs from [[apoptosis]], which kills a damaged cell to protect the body from harm.

==References==
((reflist))

== External links ==
((Medical resources
|  DiseasesDB     =  
|  ICD10          = ((ICD10|R68.89)) 
|  ICD9           = ((ICD9|799.89)) 
|  ICDO           =  
|  OMIM           =  
|  MedlinePlus    =  
|  eMedicineSubj  =  
|  eMedicineTopic =  
|  MeshID         = D017441
))
*((DorlandsDict|six/000070401|Necrobiosis))

((Cutaneous ketatosis, ulcer, atrophy, necrobiosis, and vasculitis))

[[Category:Cellular processes]]


((cell-biology-stub))

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