NUP188
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 5IJO
Identifiers
Aliases	NUP188, KIAA0169, hNup188, nucleoporin 188kDa, nucleoporin 188, SANDSTEF
External IDs	OMIM: 615587 MGI: 2446190 HomoloGene: 45683 GeneCards: NUP188
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q34.11 Start 128,947,699 bp[1] End 129,007,096 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 B Start 30,176,409 bp[2] End 30,234,278 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar hemisphere anterior pituitary stromal cell of endometrium gastric mucosa right uterine tube skin of abdomen left lobe of thyroid gland ganglionic eminence left uterine tube right lobe of thyroid gland Top expressed in spermatocyte spermatid seminiferous tubule maxillary prominence somite thymus secondary oocyte yolk sac molar internal carotid artery More reference expression data BioGPS n/a
Gene ontology Molecular function structural constituent of nuclear pore Cellular component nuclear pore nucleus nuclear pore inner ring nuclear envelope membrane host cell Biological process mitotic nuclear membrane disassembly viral transcription protein import into nucleus viral process RNA export from nucleus protein sumoylation protein transport mRNA transport regulation of cellular response to heat intracellular transport of virus glomerular visceral epithelial cell migration mRNA export from nucleus tRNA export from nucleus regulation of gene silencing by miRNA regulation of glycolytic process transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 23511 227699 Ensembl ENSG00000095319 ENSMUSG00000052533 UniProt Q5SRE5 Q6ZQH8 RefSeq (mRNA) NM_015354 NM_198304 RefSeq (protein) NP_056169 NP_938046 Location (UCSC) Chr 9: 128.95 – 129.01 Mb Chr 2: 30.18 – 30.23 Mb PubMed search [3] [4]
Wikidata
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Nucleoporin 188 (Nup188) is a protein that in humans is encoded by the NUP188 gene.^[5][6]

Function

Transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP188 is part of one such subcomplex.^[5]