OR2C1
Identifiers
AliasesOR2C1, OLFmf3, OR2C2P, olfactory receptor family 2 subfamily C member 1
External IDsMGI: 106182 HomoloGene: 7459 GeneCards: OR2C1
Orthologs
SpeciesHumanMouse
Entrez

4993

18312

Ensembl

ENSG00000168158

ENSMUSG00000059043

UniProt

O95371

P23275

RefSeq (mRNA)

NM_012368

NM_008762

RefSeq (protein)

NP_036500

NP_032788

Location (UCSC)Chr 16: 3.36 – 3.36 MbChr 16: 3.65 – 3.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2C1 is a protein that in humans is encoded by the OR2C1 gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

Ligands

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000168158 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000059043 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Centola M, Chen X, Sood R, Deng Z, Aksentijevich I, Blake T, Ricke DO, Chen X, Wood G, Zaks N, Richards N, Krizman D, Mansfield E, Apostolou S, Liu J, Shafran N, Vedula A, Hamon M, Cercek A, Kahan T, Gumucio D, Callen DF, Richards RI, Moyzis RK, Doggett NA, Collins FS, Liu PP, Fischel-Ghodsian N, Kastner DL (Jan 1999). "Construction of an ~700-kb Transcript Map Around the Familial Mediterranean Fever Locus on Human Chromosome 16p13.3". Genome Res. 8 (11): 1172–91. doi:10.1101/gr.8.11.1172. PMC 310791. PMID 9847080.
  6. ^ a b "Entrez Gene: OR2C1 olfactory receptor, family 2, subfamily C, member 1".
  7. ^ a b Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD (March 2009). "Odor coding by a Mammalian receptor repertoire". Science Signaling. 2 (60): ra9. doi:10.1126/scisignal.2000016. PMC 2774247. PMID 19261596.

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


G protein-coupled receptors: olfactory receptors
Categories