OR2J2
Identifiers
AliasesOR2J2, OR6-19, OR6-8, OR6.3.8, ORL684, dJ80I19.4, hs6M1-6, olfactory receptor family 2 subfamily J member 2
External IDsHomoloGene: 88922 GeneCards: OR2J2
Orthologs
SpeciesHumanMouse
Entrez

26707

n/a

Ensembl

ENSG00000204700

n/a

UniProt

O76002

n/a

RefSeq (mRNA)

NM_030905

n/a

RefSeq (protein)

NP_112167

n/a

Location (UCSC)Chr 6: 29.17 – 29.18 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 2J2 is a protein that in humans is encoded by the OR2J2 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

Ligands

Agonists include:[4]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000204700 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: OR2J2 olfactory receptor, family 2, subfamily J, member 2".
  4. ^ Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD (March 2009). "Odor coding by a Mammalian receptor repertoire". Science Signaling. 2 (60): ra9. doi:10.1126/scisignal.2000016. PMC 2774247. PMID 19261596.

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


G protein-coupled receptors: olfactory receptors
Categories