OR4B1
Identifiers
Aliases	OR4B1, OR11-106, OST208, olfactory receptor family 4 subfamily B member 1
External IDs	MGI: 109303 HomoloGene: 110550 GeneCards: OR4B1
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11p11.2 Start 48,216,810 bp[1] End 48,217,739 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 E1 Start 89,966,617 bp[2] End 89,972,640 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in olfactory bulb BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 119765 18331 Ensembl ENSG00000175619 ENSMUSG00000075066 UniProt Q8NGF8 n/a RefSeq (mRNA) NM_001005470 NM_010980 RefSeq (protein) NP_001005470 n/a Location (UCSC) Chr 11: 48.22 – 48.22 Mb Chr 2: 89.97 – 89.97 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 4B1 is a protein that in humans is encoded by the OR4B1 gene.^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[5]