|Formed||May 11, 1976|
|Headquarters||Eisenhower Executive Office Building|
725 17th Street NW, Washington, D.C., U.S.
|Parent agency||Executive Office of the President|
|Part of a series on the|
The Office of Science and Technology Policy (OSTP) is a department of the United States government, part of the Executive Office of the President (EOP), established by United States Congress on May 11, 1976, with a broad mandate to advise the President on the effects of science and technology on domestic and international affairs.
The director of this office is traditionally colloquially known as the Science Advisor to the President. The most recent appointed director was mathematician and geneticist Eric Lander who was sworn in on June 2, 2021. Lander resigned February 18, 2022 following allegations of misconduct.
On February 16, 2022, the Biden administration announced that deputy director Alondra Nelson would serve as acting director and former NIH director Francis Collins would serve as acting science advisor. Both assumed positions on February 18, 2022. Arati Prabhakar has been nominated to serve as Director of the Office of Science and Technology Policy.
On August 25, 2022 OSTP issued guidance to make all federally funded research in the USA freely available without delay. 
President Richard M. Nixon eliminated the President's Science Advisory Committee after his second Science Advisor, Edward E. David Jr., resigned in 1973, rather than appointing a replacement. In 1975, the American Physical Society president Chien-Shiung Wu met with the new president Gerald Ford to reinstate a scientific body of advisors for the executive branch and the president, which President Ford concurred to do. The United States Congress then established the OSTP in 1976 with a broad mandate to advise the President and others within the Executive Office of the President on the effects of science and technology on domestic and international affairs. The 1976 Act also authorizes OSTP to lead inter-agency efforts to develop and to implement sound science and technology policies and budgets and to work with the private sector, state and local governments, the science and higher education communities, and other nations toward this end.
Under President Donald Trump, OSTP's staff dropped from 135 to 45 people. The OSTP director position remained vacant for over two years, the longest vacancy for the position since the office's founding. Kelvin Droegemeier, an atmospheric scientist who previously served as the vice president of research at the University of Oklahoma, was nominated for the position on August 1, 2018 and confirmed by the Senate on January 2, 2019.
Michael Kratsios was nominated by President Trump to be the fourth Chief Technology Officer of the United States and associate director of OSTP in March 2019 and was unanimously confirmed by the Senate on August 1, 2019. During Trump's tenure, Droegemeier also managed the National Science and Technology Council.
President Joe Biden named, and the Senate later unanimously confirmed, Eric Lander as head of the Office of Science and Technology Policy, which is a cabinet-level post. Lander resigned in February 2022 following reports that engaged in abusive conduct against both subordinates and other White House officials.
In 2022, The White House Office of Science and Technology Policy held a roundtable discussion with some of the nation’s leading scientists to discuss the need to combat the climate crisis and counter arguments for delaying climate action. It is the first time that the White House has recognized scientists who study the climate denial operation run by the fossil fuel industry.
On August 8th, 2022, President Joe Biden signed into law the CHIPS and Science Act which included a provision to create a blockchain and cryptocurrency specialist advisory position under the OSTP to be established and appointed by the Director.
Key positions vary among administrations and are not always published online. Current deputy directors are listed alphabetically by portfolio and do not indicate an order of rank.
|1||H. Guyford Stever||Gerald Ford||1976–1977|
|2||Frank Press||Jimmy Carter||1977–1981|
|–||Benjamin Huberman (acting)||Ronald Reagan||1981|
|3||George A. Keyworth, II||1981–1985|
|–||John P. McTague (acting)||1986|
|–||Richard G. Johnson (acting)||1986|
|4||William Robert Graham||1986–1989|
|–||Thomas P. Rona (acting)||1989|
|–||William G. Wells (acting)||George H. W. Bush||1989|
|5||D. Allan Bromley||1989–1993|
|6||John H. Gibbons||Bill Clinton||1993–1998|
|–||Kerri-Ann Jones (acting)||1998|
|7||Neal F. Lane||1998–2001|
|–||Rosina Bierbaum (acting)||George W. Bush||2001|
|–||Clifford Gabriel (acting)||2001|
|8||John H. Marburger III||2001–2009|
|–||Ted Wackler (acting)||Barack Obama||2009|
|–||Ted Wackler (acting)||Donald Trump||2017–2019|
|–||Kei Koizumi (acting)||Joe Biden||2021|
|–||Alondra Nelson (acting)||2022–present|