Onyeka may refer to:

As a forename

• Onyeka Nubia, British historian and author
• Onyeka Onwenu (born 1952), Nigerian singer/songwriter, actress, and activist
• Onyeka Ibe (born 1971) Nigerian-American painter
• Onyeka Ibezim (born 1978), Nigerian politician
• Onyeka Akumah (born 1984), Nigerian entrepreneur
• Odafa Onyeka Okolie (born 1985), Nigerian former professional footballer
• Onyeka Nwelue (born 1988), Nigerian writer, jazz musician and film-maker
• Onyeka Azike (born 1990), Nigerian weightlifter.
• Onyeka Osemene (born 1995), Nigerian football player
• Onyeka Okongwu (born 2000), American professional basketball player

As a surname

• Ikechukwu Onyeka, Nigerian film director
• Celestina Onyeka (born 1984), Nigerian former footballer
• Godfrey Onyeka (born 1994), professional Canadian footballer
• Nakas Onyeka (born 1995), former professional Canadian footballer
• Kene Onyeka (born 1996), professional Canadian footballer
• Frank Onyeka (born 1998), Nigerian professional footballer
• Tyreece Onyeka (born 2001), English professional footballer