Orvar Swenson (7 February 1909 – 13 April 2012) was a Swedish-born American pediatric surgeon. He discovered the cause of Hirschsprung's disease and in 1948, with Alexander Bill, performed the first pull-through operation in a child with megacolon, which then became a treatment for the disease.
Initially a resident in pathology, he soon became an assistant professor of pediatric surgery at Harvard and later moved to Boston's Floating Hospital for Children as surgeon-in-chief, where he was the first pediatric surgeon on the staff at the hospital and where he began his research in Hirschsprung's disease. Subsequently, he became surgeon-in-chief of Children's Memorial Hospital, where he remained until his retirement in 1973.
Swenson was born in Helsingborg, Sweden, in 1909.[1] His parents, Amanda and Carl Albert Swenson, were missionaries for the Community of Christ and relocated their family to Independence, Missouri, in 1917.[1] Both parents died when Orvar was a teenager, and he and his brother Alvin lived in a boarding house where they started a business, Woodcraft, which sold fire-by-friction sets, bows and arrows, and field hockey sticks.[1] Orvar graduated from William Chrisman High School in 1929 and William Jewell College in 1933.[1][2] The same year, Orvar and Alvin were admitted to Harvard Medical School, where they successfully petitioned the dean to be placed in the same class so that they could share textbooks in order to save money.[3] They graduated from Harvard in 1937.[4]
Career
Swenson began his medical career as an intern at Ohio State University. After a year, he returned to Boston to work at Boston Children's Hospital and Peter Bent Brigham Hospital. Initially a resident in pathology, he took a residency in surgery from 1939 to 1945,[4] after which he became an assistant professor of pediatric surgery at Harvard while working on the pediatric surgical staff at Boston Children's Hospital.[2] In 1949 he moved to Boston's Floating Hospital for Children as surgeon-in-chief, making him the first pediatric surgeon on the staff at the hospital.[2][4] Subsequently, he moved to Chicago in 1960 to become the surgeon-in-chief of Children's Memorial Hospital, where he remained until his retirement in 1973.[2] After his retirement from clinical practice, he moved to Miami and taught at the University of Miami until 1980.[4]
Hirschsprung's disease
Swenson's main contributions to pediatric surgery focused on Hirschsprung's disease, a congenital disease in which nerves are absent from part of the colon, causing constipation and megacolon (abnormal dilation of the colon). He began his research on the condition while he was a surgical resident in Boston.[2] He discovered that the disease was caused by an absence of ganglion cells in the rectum, but before clarity on the cause of the disease, with Alexander Bill, they designed a surgical procedure to remove the abnormal section of the bowel, pull-through the normal bowel and join it to the remaining parts of the normal bowel.[3][5]
When Swenson performed the procedure in 1948, it was the first successful surgical correction of megacolon.[4] It was not however a real Hirschsprung's, as Swenson clarified later in an interview when Bill had said to him that "this is just a weird case; it's not a real Hirschsprung's disease".[6][7]
This operation, however, became the only procedure that treated Hirschsprung's disease and became known as the "Swenson pull-through". He described the hallmark clinical and radiological markers of Hirschsprung's disease in newborns and showed that the only way to make a definitive diagnosis was to perform a full-thickness rectal biopsy. Swenson subsequently followed his patients for a number of years.[3] Over his career, he traveled to India, Australia, South America, Europe and Canada to demonstrate his procedure.[2]
Swenson married Melva Elizabeth Criley in 1941; they had three daughters.[1] He died in Charleston, South Carolina, in 2012, aged 103.[1][3]
Selected publications
Swenson, O; Bill, AH Jr (1948). "Resection of rectum and rectosigmoid with preservation of the sphincter for benign spastic lesions producing megacolon; an experimental study". Surgery. 24 (2): 212–20. PMID18872852.
Swenson, O; Neuhauser, EB; Pickett, LK (1949). "New concepts of the etiology, diagnosis and treatment of congenital megacolon (Hirschsprung's disease)". Pediatrics. 4 (2): 201–9. doi:10.1542/peds.4.2.201. PMID18137843. S2CID1265978.
Swenson, O (1950). "A new surgical treatment for Hirschsprung's disease". Surgery. 28 (2): 371–83. PMID15442813.
Swenson, Orvar; Segnitz, Richard H.; Shedd, Robert H. (1951). "Hirschsprung's disease". The American Journal of Surgery. 81 (3): 341–347. doi:10.1016/0002-9610(51)90239-5. PMID14819481.
Swenson, O (August 1989). "My early experience with Hirschsprung's disease". J. Pediatr. Surg. 24 (8): 839–44, discussion 844–5. doi:10.1016/s0022-3468(89)80549-4. PMID2671336.
^Swenson, Orvar (24 August 1989). "My early experience with Hirschsprung's disease". Journal of Pediatric Surgery. 24 (8): 844–845. doi:10.1016/s0022-3468(89)80549-4. PMID2671336.
^Bill, Alexander H. Jr. (1959). "Congenital Abnormalities of the Colon, Rectum and Anus". Surgical Clinics of North America. 39 (5): 1165–1177. doi:10.1016/S0039-6109(16)35881-9. PMID13800688.
