Poly-[1-6]--D-glucopyranosyl-[1-3]--D-glucopyranose glucan (PGG glucan, proprietary name Betafectin)^[1] is an anti-infective agent and a form or type of beta-glucan.

Betafectin is a PGG-glucan, a novel β-(1,6) branched β-(1,3) glucan, purified from the cell walls of Saccharomyces cerevisiae.^[2]

It is a macrophage-specific immunomodulator.