Pentalenic acid synthase
Identifiers
EC no.1.14.15.11
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Pentalenic acid synthase (EC 1.14.15.11, CYP105D7, sav7469 (gene)) is an enzyme with systematic name 1-deoxypentalenate,reduced ferredoxin:O2 oxidoreductase.[1] This enzyme catalyses the following chemical reaction

1-deoxypentalenate + reduced ferredoxin + O2 pentalenate + oxidized ferredoxin + H2O

Pentalenic acid synthase is a heme-thiolate enzyme (P-450).

References

  1. ^ Takamatsu S, Xu LH, Fushinobu S, Shoun H, Komatsu M, Cane DE, Ikeda H (January 2011). "Pentalenic acid is a shunt metabolite in the biosynthesis of the pentalenolactone family of metabolites: hydroxylation of 1-deoxypentalenic acid mediated by CYP105D7 (SAV_7469) of Streptomyces avermitilis". The Journal of Antibiotics. 64 (1): 65–71. doi:10.1038/ja.2010.135. PMC 3030646. PMID 21081950.

External links

Cytochromes, oxygenases: cytochrome P450 (Most belong to EC 1.14)
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