Peyton is an English surname and a unisex given name. In Ireland it is known to have been among the anglicized forms of Ó Peatáin.

Surname

• Balie Peyton (1803–1878), American lawyer and politician
• Ben Peyton (born 1977), British actor
• Benny Peyton (c. 1890 – 1965), American jazz drummer
• Bob Peyton (born 1954), English former footballer
• Brad Peyton (born 1980), Canadian-born film director
• Caroline Peyton (1951–2021), American singer and songwriter
• Craig Peyton (born 1953), American producer
• Dave Peyton (c. 1885 – 1955), American songwriter, pianist, and arranger
• Edward Peyton (died 1749), officer of the Royal Navy
• Elizabeth Peyton (born 1965), American painter
• Ephraim G. Peyton (1802–after 1876), justice of the Mississippi Supreme Court
• Gerry Peyton (born 1956), English football player
• Sir Henry Peyton, 1st Baronet (1736–1789), MP for Cambridgeshire 1782–89
• Sir Henry Peyton, 2nd Baronet (1779–1854), MP for Cambridgeshire in 1802
• Sir Henry Peyton, 3rd Baronet (1804–1866), MP for Woodstock 1837–38
• Herb Peyton (born 1932), American entrepreneur and founder of Gate Petroleum in Jacksonville, Florida
• Jane Peyton (1870–1946), American actress
• John Peyton (disambiguation), the name of several people
• Joseph Hopkins Peyton (1808–1845), American politician
• K. M. Peyton (1929–2023), British author
• Kate Peyton (1965–2005), Senior Producer for the BBC Johannesburg Bureau 2002–05
• Kim Peyton (1957–1986), competitive freestyle swimmer, Gold medalist for the United States at the 1976 Montreal Summer Olympics
• Malcolm Peyton (born 1932), American composer, concert director, conductor, and teacher
• Mike Peyton (1921–2017), British cartoonist
• Noel Peyton (born 1935), Irish former professional footballer
• Oliver Peyton (born 1963), Irish restaurateur and judge on the BBC television series Great British Menu
• Patrick Peyton (1909–1992), Irish-born American priest
• Robert Ludwell Yates Peyton (1822–1863), American politician and soldier
• Rog Peyton (born 1942), science fiction bookseller and editor
• Samuel Peyton (1804–1870), U.S. Representative from Kentucky
• Shelly Peyton, American chemist
• Tony Peyton (1922–2007), member of the Harlem Globetrotters basketball team
• Warren Peyton (born 1979), English footballer
• Whitney Peyton, American rapper from Philadelphia, Pennsylvania
• William Peyton (1866–1931), British general

Given name

• Peyton C. March (1864–1955), American soldier and Army Chief of Staff
• Peyton Evans (1892–1972), former head coach of the University of Virginia college football program from 1916 to 1916
• Peyton Gordon (1870–1946), United States federal judge
• Peyton H. Colquitt (1831–1863), Confederate Officer
• Peyton Hendershot (born 1999), American football player
• Peyton Hillis (born 1986), American football player
• Peyton Elizabeth Lee (born 2004), American actress
• Peyton Kennedy (born 2004), American actress
• Peyton List (born 1986), American actress
• Peyton List (born 1998), American actress
• Peyton M. Magruder (1911–1982), aircraft designer
• Peyton Manning (born 1976), American football player
• Peyton Meyer (born 1998), American actor
• Peyton R. Helm, eleventh president of Muhlenberg College
• Peyton Randolph (governor) (1779–1828), American politician
• Peyton Randolph (1721–1775), American politician
• Peyton Reed (born 1964), American director
• Peyton Sellers (born 1983), American race car driver, competing in the NASCAR Nationwide Series
• Peyton Short (1761–1825), land speculator and politician in Kentucky
• Peyton Siva (born 1990), American basketball player
• Peyton Thompson (born 1990), American football player
• Peyton Watson (born 2002), American basketball player
• Peyton Young (born 1945), American game theorist

Fictional characters

• Peyton (Chaotic), in the television series Chaotic
• Peyton Charles, in the television series iZombie
• Peyton Driscoll, in the television series CSI: NY
• Peyton Farquhar, character in the short story An Occurrence at Owl Creek Bridge by Ambrose Bierce
• Peyton Kelly, in the 2007 film The Game Plan
• Peyton Leverett, in the 2011 film Sharpay's Fabulous Adventure
• Peyton Loftis, in the 1951 novel Lie Down in Darkness by William Styron
• Peyton Mott, in the 1992 film The Hand That Rocks the Cradle
• Peyton Sawyer, character in the television series One Tree Hill
• Peyton Westlake, in the 1990 film Darkman
• Kelly Peyton, character in the television series Alias
• Peyton Bragg, character in the 1959 novel Alas, Babylon