Physiological agonism describes the action of a substance which ultimately produces the same effects in the body as another substance—as if they were both agonists at the same receptor—without actually binding to the same receptor. Physiological antagonism describes the behavior of a substance that produces effects counteracting those of another substance (a result similar to that produced by an antagonist blocking the action of an agonist at the same receptor) using a mechanism that does not involve binding to the same receptor.

Examples

Physiological agonists

Physiological antagonists

References

  1. ^ Pietrapiana, D; Sala, M; Prat, M; Sinigaglia, F (Aug 15, 2005). "Met identification on human platelets: role of hepatocyte growth factor in the modulation of platelet activation". FEBS Letters. 579 (20): 4550–4. doi:10.1016/j.febslet.2005.06.072. PMID 16083876. S2CID 39722975.