In Greek mythology, the name Polymela or Polymele (Ancient Greek: Πολυμήλη "many songs", derived from polys, "many" and melos "song") may refer to the following figures:

• Polymele, daughter of Autolycus and one of the possible mothers of Jason by Aeson, King of Iolcus.^[1] She was also called Polymede^[2] or Polypheme,^[3] otherwise the mother of the hero was either Amphinome,^[4] Theognete, daughter of Laodicus,^[5] Rhoeo,^[6] Arne or Scarphe.^[7]
• Polymele, daughter of Peleus and one of the possible mothers of Patroclus by Menoetius,^[8] the other two being Sthenele^[9] and Periopis;^[10] some refer to her as "Philomela".^[11][12] In some accounts, Damocrateia, daughter of Aegina and Zeus, was also called the wife of Menoetius and mother of Patroclus.^[13]
• Polymele, wife of Thestor and mother of Calchas^[14] and possibly also of Leucippe and Theonoe.^[15]
• Polymele, daughter of Phylas and wife of Echecles. She was loved by Hermes, who spotted her while she was performing a ritual dance in honor of Artemis, and had by him a son, Eudoros.^[16]
• Polymele, daughter of Aeolus. When Odysseus visited their island,^[17] he fell in love with her and lay with her secretly. Soon after the guest's departure, Aeolus discovered his daughter crying over some spoils from Troy which Odysseus had given to her as presents. Outraged, he was about to exact vengeance upon Polymele, but his son Diores, who was in love with his own sister, intervened and implored Aeolus to marry her to him, to which Aeolus consented.^[18]