Poole is a surname. Notable people with the surname include:

• Adalbert Poole (1881–1970), Canadian politician
• Andrew Poole (cricketer) (born 1967), English cricketer
• Andy Poole (footballer) (born 1960), English footballer
• Austin Lane Poole (1889–1963), British mediaevalist
• Barney Poole (1923–2005), American football player
• Ben Poole, British blues rock guitarist, singer, and songwriter.
• Bertram William Henry Poole (1880–1957), British-American philatelist
• Brian Poole (born 1941), British singer and entertainer, lead singer of Brian Poole and the Tremeloes
• Bruce Poole (born 1959), American politician
• Cecil Charles Poole (1885–1970), British politician
• Cecil F. Poole (1914–1997), American lawyer and judge
• Charles Poole (1874–1941), New Zealand politician
• Charles Lane Poole (1885–1970), Australian forester
• Charlie Poole (1892–1931), American banjo player
• Christopher "Kit" Poole (1875–1965), Irish Citizen Army officer during the 1916 Easter Rising
• Christopher Poole (born c.1988), American founder of web sites 4chan and Canvas
• Cyril Poole (1921–1996), English cricketer and footballer
• Daniel Poole (1882–1959), Australian seaman and soldier
• David Poole (disambiguation), several people
• Dianne Poole (born 1949), Canadian politician
• Dick Poole (disambiguation), several people
• Earl Lincoln Poole (1891–1972), American wildlife artist, sculptor, author and naturalist
• Ed Poole (1874–1919), American baseball player
• Elizabeth Poole (1588–1654), English settler in Plymouth Colony
• Eric Poole (1885–1916), British Army officer of World War I
• Eric Joseph Poole (1907–1969), Canadian politician
• Eric Poole, fictional character and primary antagonist in the Robert Cormier novel Tenderness
• Ernest Poole (1880–1950), American novelist
• Eugene J. Poole (1880–1958), American politician
• Fanny Huntington Runnells Poole (1863–1940), American writer, book reviewer
• Frank Poole, fictional character in Arthur C. Clarke's Space Odyssey science fiction series
• Freddi Poole (born 1946), American singer
• Frederic Slaney Poole (1845–1936), Anglican priest in South Australia
• Gary Poole (born 1967), English footballer
• George Temple-Poole (1856–1934), British architect
• Glenn Poole (born 1981), English footballer
• Grace Poole, fictional character in Charlotte Brontë's 1847 novel Jane Eyre
• Harold Poole (1943–2014), American bodybuilder
• Henry Poole (disambiguation), several people
• Hester Martha Poole (1833–1932), American writer, artist, advocate
• Horatio Nelson Poole (1884–1949), American painter and printmaker
• Ike Poole (1915–2002), American basketball player
• James Poole (disambiguation), several people
• Jim Poole (disambiguation), several people
• Joe Poole (1923–1990), English footballer
• John Poole (disambiguation), several people
• Jon Poole (born 1969), English singer and songwriter
• Jonas Poole (c.1566–1612), English explorer, sealer, and whaler
• Jordan Poole (born 1999), American basketball player
• Karen Poole (born 1971), British singer and songwriter, daughter of Brian
• Keith Poole (born 1974), American football player
• Kenny Poole (1947–2006), American jazz guitarist
• Kevin Poole (born 1963), English football player
• Larry Poole, American actor and film producer
• Lynn Poole (1910–1969), American science writer and broadcaster
• Malcolm Poole (born 1949), Australian field hockey player
• Marin Poole (born 1984), American beauty queen
• Mark Poole, American illustrator
• Marshall Scott Poole (born 1951), American communication researcher
• Matthew Poole (1624–1679), English theologian
• Max Poole (born 2003), British cyclist
• Minor Butler Poole (1920–1942), United States Navy sailor, Navy Cross recipient
• Nate Poole (born 1977), American football player
• Nick Poole (born 1973), Canadian ice hockey player
• Oliver Poole, 1st Baron Poole (1911–1993), British politician, soldier and businessman
• Olivia Poole (1889–1975), American inventor
• Paul Falconer Poole (1806–1879), British painter
• Phil Poole (born 1959), American Democratic politician
• Phillip Poole (born 1981), British ice dancer
• Ray Poole (1921–2008), American football player
• Reg Poole (born 1944), Australian musician
• Reg Poole (footballer) (1942–2021), Australian footballer
• Regan Poole (born 1998), Welsh football player
• Reginald Lane Poole (1857–1939), British historian
• Reginald Stuart Poole (1832–1895), English orientalist
• Sir Reginald Ward Poole (1864–1941), British solicitor, President of the Law Society
• Robert Poole (disambiguation), multiple people
• Roger Poole (1946-2015), British trade union official
• Rose M. Poole (1880-1963), American businesswoman and politician
• Russell Poole (1956–2015), American policeman from Los Angeles
• Sandra Le Poole (born 1959), Dutch field hockey player
• Shelly Poole (born 1972), English songwriter and singer, daughter of Brian
• Sophia Lane Poole (1804–1891), English orientalist
• Stafford Poole (1930–2020), American historian
• Stanley Lane-Poole (1854–1931), British orientalist, archaeologist and writer
• Steven Poole (born 1972), British writer and journalist
• Suzelle Poole (born 1940), British ballet dancer and poet
• Teresa Poole (born 1964), Australian Paralympic cyclist
• Terry Poole (disambiguation)
• Theodore L. Poole (1840–1900), American politician from New York
• Thomas Poole (disambiguation), several people
• Trevor Poole (born 1964), Australian footballer
• Tyrone Poole (born 1972), American football player
• Vicki Poole, New Zealand diplomat
• Wakefield Poole (1936–2021), American dancer, choreographer, and director
• Will Poole (born 1981), American football player
• William Poole (disambiguation), several people
• William Frederick Poole (1821-1894), American bibliographer and librarian