Pratyusha or Prathyusha is a feminine given name found among Indian people.^{[citation needed]} Notable people with this name include:

• Prathyusha (1981 – 2002), an Indian actress in Telugu and Tamil language cinema
• Pratyusha Banerjee (1991 – 2016), an Indian television actress
• Pratyusha Rajeshwari Singh, a politician from Odisha state, India, serving since 2014