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((Short description|Type of heart murmur))
((more citations needed|date=January 2015))
A '''presystolic murmur''', also called '''presystolic accentuation''', is a type of [[diastolic heart murmur]] typically associated with the opening snap in [[mitral valve stenosis]].  It is heard following the middiastolic rumble of the stenotic valve,<ref name=topol>Eric J. Topol. [https://books.google.com/books?id=35zSLWyEWbcC The Topol Solution: Textbook of Cardiovascular Medicine], Third Edition with DVD, Plus Integrated Content Website, Volume 355. Lippincott Williams & Wilkins, Oct 19, 2006; page 222. ((ISBN|0781770122))</ref> during the [[Diastasis (physiology)|diastasis]] phase, making it a "late diastolic" murmur.

The murmur is heard due to antegrade flow of blood through a progressively narrowing mitral opening during the end of the [[atrial systole]]. This antegrade flow through the mitral valve before it completely closes appears to be the result of a pressure gradient at the end of diastole.<ref name=topol /> As its name so indicates, the presystolic murmur is heard before the mitral valve produces the S1 heart sound.

Less often, a presystolic murmur can be heard when a right [[atrial myxoma]] causes a tricuspid valve obstruction to blood flow.<ref name=topol />

==References==
((Reflist))

((Cardiovascular system symptoms and signs))

[[Category:Heart murmurs]]


((med-sign-stub))

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