| Promyelocyte | |
|---|---|
 Promyelocyte from bone marrow examination | |
| Details | |
| Precursor | Myeloblast |
| Gives rise to | Myelocyte |
| Location | Bone marrow |
| Identifiers | |
| TH | H2.00.04.3.04003 |
| Anatomical terms of microanatomy | |
A promyelocyte (or progranulocyte) is a granulocyte precursor, developing from the myeloblast and developing into the myelocyte. Promyelocytes measure 12–20 microns in diameter. The nucleus of a promyelocyte is approximately the same size as a myeloblast but their cytoplasm is much more abundant.[1] They also have less prominent nucleoli than myeloblasts and their chromatin is more coarse and clumped.[1] The cytoplasm is basophilic and contains primary red/purple granules.[1]
![Bone marrow smear from a patient with acute promyelocytic leukemia, showing characteristic abnormal promyelocytes.[2]](/en/File:Cytology_of_acute_promyelocytic_leukemia,_annotated.png)
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