RBBP9
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2QS9
Identifiers
Aliases	RBBP9, BOG, RBBP10, retinoblastoma binding protein 9, RB binding protein 9, serine hydrolase
External IDs	OMIM: 602908 MGI: 1347074 HomoloGene: 4816 GeneCards: RBBP9
Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20p11.23 Start 18,486,540 bp[1] End 18,497,225 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 G1 Start 144,384,185 bp[2] End 144,392,789 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in retinal pigment epithelium bronchial epithelial cell ganglionic eminence stromal cell of endometrium palpebral conjunctiva endothelial cell gallbladder islet of Langerhans left adrenal gland Achilles tendon Top expressed in left lung lobe olfactory epithelium seminal vesicula sciatic nerve median eminence kidney dermis proximal tubule epithelium of stomach utricle More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding hydrolase activity Cellular component nucleus nucleoplasm cytoplasm Biological process regulation of cell population proliferation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10741 26450 Ensembl ENSG00000089050 ENSMUSG00000027428 UniProt O75884 O88851 RefSeq (mRNA) NM_006606 NM_153328 NM_015754 RefSeq (protein) NP_006597 NP_056569 Location (UCSC) Chr 20: 18.49 – 18.5 Mb Chr 2: 144.38 – 144.39 Mb PubMed search [3] [4]
Wikidata
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Putative hydrolase RBBP9 is an enzyme that in humans is encoded by the RBBP9 gene.^[5][6][7]

Function

The protein encoded by this gene is a retinoblastoma binding protein that may play a role in the regulation of cell proliferation and differentiation. Two alternatively spliced transcript variants of this gene with identical predicted protein products have been reported, one of which is a nonsense-mediated decay candidate.^[7]

Interactions

RBBP9 has been shown to interact with Retinoblastoma protein.^[5]