Regulation is a quarterly periodical about policy published by the Cato Institute. It was started as a bimonthly magazine^[1] in 1977 by the American Enterprise Institute and acquired by Cato in 1989. Past editors have included former Supreme Court justice Antonin Scalia,^[2] Murray Weidenbaum, Christopher DeMuth, Walter Olson, and Peter Huber.^[3] Peter Van Doren has edited the magazine since 1999.

In the late 1970s and early 1980s, the magazine was pivotal in promoting deregulation and the importance of cost–benefit analysis.^[3]