In lysosomal digestion, residual bodies are vesicles containing indigestible materials.^[1] Residual bodies are either secreted by the cell via exocytosis (this generally only occurs in macrophages), or they become lipofuscin granules that remain in the cytosol indefinitely. Longer-living cells like neurons and muscle cells usually have a higher concentration of lipofuscin than other more rapidly proliferating cells.