Ro20-8552
Legal status
Legal status
Identifiers
  • 8-chloro-5-(2-fluorophenyl)-7-methyl-1,3-dihydro-1,4-benzodiazepin-2-one
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC16H12ClFN2O
Molar mass302.73 g·mol−1
3D model (JSmol)
  • CC1=CC2=C(C=C1Cl)NC(=O)CN=C2C3=CC=CC=C3F
  • InChI=1S/C16H12ClFN2O/c1-9-6-11-14(7-12(9)17)20-15(21)8-19-16(11)10-4-2-3-5-13(10)18/h2-7H,8H2,1H3,(H,20,21)
  • Key:GANKBGRUGXCJBG-UHFFFAOYSA-N

Ro20-8552 is a benzodiazepine derivative with sedative and anxiolytic effects, which has been sold as a designer drug.[1][2]

See also

References

  1. ^ Zhang W, Koehler KF, Harris B, Skolnick P, Cook JM (March 1994). "Synthesis of benzo-fused benzodiazepines employed as probes of the agonist pharmacophore of benzodiazepine receptors". Journal of Medicinal Chemistry. 37 (6): 745–57. doi:10.1021/jm00032a007. PMID 8145224.
  2. ^ Catalani V, Botha M, Corkery JM, Guirguis A, Vento A, Scherbaum N, Schifano F (July 2021). "The Psychonauts' Benzodiazepines; Quantitative Structure-Activity Relationship (QSAR) Analysis and Docking Prediction of Their Biological Activity". Pharmaceuticals. 14 (8): 720. doi:10.3390/ph14080720. hdl:2299/24928. PMC 8398354. PMID 34451817.
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