SERPINB3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2ZV6, 4ZK0, 4ZK3
Identifiers
Aliases	SERPINB3, HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, T4-A, SSCA1, serpin family B member 3
External IDs	OMIM: 600517 MGI: 2683295 HomoloGene: 130559 GeneCards: SERPINB3
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18q21.33 Start 63,655,197 bp[1] End 63,661,893 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 E2.1|1 Start 107,005,897 bp[2] End 107,011,236 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in vulva human penis bronchial epithelial cell gums trachea oral cavity body of tongue vagina periodontal fiber skin of abdomen Top expressed in thymus esophagus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function virus receptor activity protease binding cysteine-type endopeptidase inhibitor activity peptidase inhibitor activity serine-type endopeptidase inhibitor activity Cellular component nucleus vesicle cytoplasmic vesicle extracellular exosome cytoplasm extracellular region extracellular space azurophil granule lumen Biological process paracrine signaling positive regulation of cell population proliferation autocrine signaling negative regulation of catalytic activity negative regulation of JUN kinase activity positive regulation of endopeptidase activity positive regulation of epithelial to mesenchymal transition negative regulation of proteolysis negative regulation of endopeptidase activity positive regulation of cell migration viral entry into host cell negative regulation of peptidase activity neutrophil degranulation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6317 394252 Ensembl ENSG00000057149 ENSMUSG00000058017 UniProt P29508 Q6UKZ0 RefSeq (mRNA) NM_006919 NM_201376 RefSeq (protein) NP_008850 NP_958764 Location (UCSC) Chr 18: 63.66 – 63.66 Mb Chr 1: 107.01 – 107.01 Mb PubMed search [3] [4]
Wikidata
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Serpin B3 is a protein that in humans is encoded by the SERPINB3 gene.^[5][6]