SYT2
Identifiers
Aliases	SYT2, SytII, CMS7, MYSPC, synaptotagmin 2, CMS7A, CMS7B
External IDs	OMIM: 600104 MGI: 99666 HomoloGene: 22516 GeneCards: SYT2
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q32.1 Start 202,590,596 bp[1] End 202,710,454 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 E4|1 58.24 cM Start 134,574,415 bp[2] End 134,690,331 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pons external globus pallidus cerebellar vermis superior vestibular nucleus inferior olivary nucleus spinal ganglia ventral tegmental area inferior ganglion of vagus nerve postcentral gyrus Brodmann area 23 Top expressed in cerebellar cortex inferior colliculus medulla oblongata pontine nuclei medial vestibular nucleus facial motor nucleus anterior horn of spinal cord cerebellar vermis dorsal tegmental nucleus superior colliculus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function metal ion binding calcium ion binding inositol 1,3,4,5 tetrakisphosphate binding clathrin binding syntaxin binding protein binding calcium-dependent phospholipid binding SNARE binding phosphatidylserine binding Cellular component cell junction chromaffin granule membrane synaptic vesicle membrane cytoplasmic vesicle synapse integral component of membrane synaptic vesicle membrane plasma membrane clathrin-coated vesicle membrane axon dense core granule exocytic vesicle Biological process synaptic vesicle endocytosis cell differentiation neurotransmitter secretion positive regulation of dendrite extension vesicle fusion regulation of calcium ion-dependent exocytosis calcium ion-regulated exocytosis of neurotransmitter membrane organization regulation of dopamine secretion synaptic vesicle exocytosis vesicle-mediated transport calcium-ion regulated exocytosis cellular response to calcium ion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 127833 20980 Ensembl ENSG00000143858 ENSMUSG00000026452 UniProt Q8N9I0 P46097 RefSeq (mRNA) NM_001136504 NM_177402 NM_009307 NM_001355726 RefSeq (protein) NP_001129976 NP_796376 NP_033333 NP_001342655 Location (UCSC) Chr 1: 202.59 – 202.71 Mb Chr 1: 134.57 – 134.69 Mb PubMed search [3] [4]
Wikidata
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Synaptotagmin-2 is a protein that in humans is encoded by the SYT2 gene.^[5][6]