Salamanders
Temporal range:
Late Jurassic – Present,[1] 160–0 Ma
Spotted salamander, Ambystoma maculatum
Scientific classification Edit this classification
Domain: Eukaryota
Kingdom: Animalia
Phylum: Chordata
Class: Amphibia
Clade: Caudata
Order: Urodela
Duméril, 1806
Suborders

Cryptobranchoidea
Salamandroidea

Native distribution of salamanders (in green)

Salamanders are a group of amphibians typically characterized by their lizard-like appearance, with slender bodies, blunt snouts, short limbs projecting at right angles to the body, and the presence of a tail in both larvae and adults. All ten extant salamander families are grouped together under the order Urodela from the group Caudata.[2] Salamander diversity is highest in eastern North America, especially in the Appalachian Mountains; most species are found in the Holarctic realm, with some species present in the Neotropical realm.

Salamanders rarely have more than four toes on their front legs and five on their rear legs, but some species have fewer digits and others lack hind limbs. Their permeable skin usually makes them reliant on habitats in or near water or other cool, damp places. Some salamander species are fully aquatic throughout their lives, some take to the water intermittently, and others are entirely terrestrial as adults.

This group of amphibians is capable of regenerating lost limbs as well as other damaged parts of their bodies. Researchers hope to reverse engineer the regenerative processes for potential human medical applications, such as brain and spinal cord injury treatment or preventing harmful scarring during heart surgery recovery.[3] The remarkable ability of salamanders to regenerate is not just limited to limbs but extends to vital organs such as the heart, jaw, and parts of the spinal cord, showing their uniqueness compared to different types of vertebrates. ⁤⁤This ability is very remarkable for occurring without any type of scarring. ⁤⁤This has made salamanders an invaluable model organisms in scientific research aimed at understanding and achieving regenerative processes for medical advancements in human and animal biology.[4]

Members of the family Salamandridae are mostly known as newts and lack the costal grooves along the sides of their bodies typical of other groups. The skin of some species contains the powerful poison tetrodotoxin; these salamanders tend to be slow-moving and have bright warning coloration to advertise their toxicity. Salamanders typically lay eggs in water and have aquatic larvae, but great variation occurs in their lifecycles. Some species in harsh environments reproduce while still in the larval state.

Etymology

The word salamander comes from Old French salamandre from Latin salamandra from Greek σαλαμάνδρα,[5] which is used for the fire salamander.[6]

Description

X-ray image of salamander

The skin lacks scales and is moist and smooth to the touch, except in newts of the Salamandridae, which may have velvety or warty skin, wet to the touch. The skin may be drab or brightly colored, exhibiting various patterns of stripes, bars, spots, blotches, or dots. Male newts become dramatically colored during the breeding season. Cave species dwelling in darkness lack pigmentation and have a translucent pink or pearlescent appearance.[7]

Salamanders range in size from the minute salamanders, with a total length of 27 mm (1+1⁄8 in), including the tail, to the Chinese giant salamander which reaches 1.8 m (6 ft) and weighs up to 65 kg (145 lb). All the largest species are both aquatic and paedomorphic.[8] Some of the largest terrestrial salamanders, which goes through full metamorphosis, are found in the family of Pacific giant salamanders, and are much smaller.[9] Most salamanders, however, are between 10 and 20 cm (4 and 8 in) in length.[10]

Trunk, limbs and tail

An adult salamander generally resembles a small lizard, having a basal tetrapod body form with a cylindrical trunk, four limbs, and a long tail. Except in the family Salamandridae, the head, body, and tail have a number of vertical depressions in the surface which run from the mid-dorsal region to the ventral area and are known as costal grooves. Their function seems to be to help keep the skin moist by channeling water over the surface of the body.[11]

Sirens have an eel-like appearance.

Some aquatic species, such as sirens and amphiumas, have reduced or absent hind limbs, giving them an eel-like appearance, but in most species, the front and rear limbs are about the same length and project sidewards, barely raising the trunk off the ground. The feet are broad with short digits, usually four on the front feet and five on the rear. Salamanders do not have claws, and the shape of the foot varies according to the animal's habitat. Climbing species have elongated, square-tipped toes, while rock-dwellers have larger feet with short, blunt toes. The tree-climbing salamander (Bolitoglossa sp.) has plate-like webbed feet which adhere to smooth surfaces by suction, while the rock-climbing Hydromantes species from California have feet with fleshy webs and short digits and use their tails as an extra limb. When ascending, the tail props up the rear of the body, while one hind foot moves forward and then swings to the other side to provide support as the other hind foot advances.[12]

In larvae and aquatic salamanders, the tail is laterally flattened, has dorsal and ventral fins, and undulates from side to side to propel the animal through the water. In the families Ambystomatidae and Salamandridae, the male's tail, which is larger than that of the female, is used during the amplexus embrace to propel the mating couple to a secluded location. In terrestrial species, the tail moves to counterbalance the animal as it runs, while in the arboreal salamander and other tree-climbing species, it is prehensile. The tail is also used by certain plethodontid salamanders that can jump, to help launch themselves into the air.[12] The tail is used in courtship and as a storage organ for proteins and lipids. It also functions as a defense against predation, when it may be lashed at the attacker or autotomised when grabbed. Unlike frogs, an adult salamander is able to regenerate limbs and its tail when these are lost.[12]

Skin

Rough-skinned newt

The skin of salamanders, in common with other amphibians, is thin, permeable to water, serves as a respiratory membrane, and is well-supplied with glands. It has highly cornified outer layers, renewed periodically through a skin shedding process controlled by hormones from the pituitary and thyroid glands. During moulting, the skin initially breaks around the mouth, and the animal moves forwards through the gap to shed the skin. When the front limbs have been worked clear, a series of body ripples pushes the skin towards the rear. The hind limbs are extracted and push the skin farther back, before it is eventually freed by friction as the salamander moves forward with the tail pressed against the ground.[13] The animal often then eats the resulting sloughed skin.[7]

Glands in the skin discharge mucus which keeps the skin moist, an important factor in skin respiration and thermoregulation. The sticky layer helps protect against bacterial infections and molds, reduces friction when swimming, and makes the animal slippery and more difficult for predators to catch. Granular glands scattered on the upper surface, particularly the head, back, and tail, produce repellent or toxic secretions.[13] Some salamander toxins are particularly potent. The rough-skinned newt (Taricha granulosa) produces the neurotoxin tetrodotoxin, the most toxic nonprotein substance known. Handling the newts does no harm, but ingestion of even a minute fragment of skin is deadly. In feeding trials, fish, frogs, reptiles, birds, and mammals were all found to be susceptible.[14]

Mature adults of some salamander species have "nuptial" glandular tissue in their cloacae, at the base of their tails, on their heads or under their chins. Some females release chemical substances, possibly from the ventral cloacal gland, to attract males, but males do not seem to use pheromones for this purpose.[15] In some plethodonts, males have conspicuous mental glands on the chin which are pressed against the females' nostrils during the courtship ritual. They may function to speed up the mating process, reducing the risk of its being disrupted by a predator or rival male.[16] The gland at the base of the tail in Plethodon cinereus is used to mark fecal pellets to proclaim territorial ownership.[15]

Senses

The front part of the olm's head carries sensitive chemo-, mechano-, and electroreceptors.
Biofluorescence can be observed across various salamander species

Olfaction in salamanders plays a role in territory maintenance, the recognition of predators, and courtship rituals, but is probably secondary to sight during prey selection and feeding. Salamanders have two types of sensory areas that respond to the chemistry of the environment. Olfactory epithelium in the nasal cavity picks up airborne and aquatic odors, while adjoining vomeronasal organs detect nonvolatile chemical cues, such as tastes in the mouth. In plethodonts, the sensory epithelium of the vomeronasal organs extends to the nasolabial grooves, which stretch from the nostrils to the corners of the mouth. These extended areas seem to be associated with the identification of prey items, the recognition of conspecifics, and the identification of individuals.[17]

The eyes of most salamanders are adapted primarily for vision at night. In some permanently aquatic species, they are reduced in size and have a simplified retinal structure, and in cave dwellers such as the Georgia blind salamander, they are absent or covered with a layer of skin. In amphibious species, the eyes are a compromise and are nearsighted in air and farsighted in water. Fully terrestrial species such as the fire salamander have a flatter lens which can focus over a much wider range of distances.[18] To find their prey, salamanders use trichromatic color vision extending into the ultraviolet range, based on three photoreceptor types that are maximally sensitive around 450, 500, and 570 nm.[19] The larvae, and the adults of some highly aquatic species, also have a lateral line organ, similar to that of fish, which can detect changes in water pressure.[7]

All salamanders lack middle ear cavity, eardrum and eustachian tube, but have an opercularis system like frogs, and are still able to detect airborne sound.[20][21] The opercularis system consists of two ossicles: the columella (equivalent to the stapes of higher vertebrates) which is fused to the skull, and the operculum. An opercularis muscle connects the latter to the pectoral girdle, and is kept under tension when the animal is alert.[22] The system seems able to detect low-frequency vibrations (500–600 Hz), which may be picked up from the ground by the fore limbs and transmitted to the inner ear. These may serve to warn the animal of an approaching predator.[23]

Salamanders are usually considered to have no voice and do not use sound for communication in the way that frogs do; however, in mating system they communicate by pheromone signaling; some species can make quiet ticking. clicking, squeaks or popping noises,[24] perhaps by the opening and closing of valves in the nose. Most salamanders lack vocal cords, but a larynx is present in the mudpuppy (Necturus) and some other species, and the Pacific giant salamanders and a few others have a large larynx and bands known as plicae vocales.[25] The California giant salamander can produce a bark or rattle, and a few species can squeak by contracting muscles in the throat. The arboreal salamander can squeak using a different mechanism; it retracts its eyes into its head, forcing air out of its mouth. The ensatina salamander occasionally makes a hissing sound, while the sirens sometimes produce quiet clicks, and can resort to faint shrieks if attacked. Similar clicking behaviour was observed in two European newts Lissotriton vulgaris and Ichthyosaura alpestris in their aquatic phase.[26] Vocalization in salamanders has been little studied and the purpose of these sounds is presumed to be the startling of predators.[27]

Salamanders need moist environments to respire through their skin.

Respiration

Respiration differs among the different species of salamanders, and can involve gills, lungs, skin, and the membranes of mouth and throat. Larval salamanders breathe primarily by means of gills, which are usually external and feathery in appearance. Water is drawn in through the mouth and flows out through the gill slits. Some neotenic species such as the mudpuppy (Necturus maculosus) retain their gills throughout their lives, but most species lose them at metamorphosis. The embryos of some terrestrial lungless salamanders, such as Ensatina, that undergo direct development, have large gills that lie close to the egg's surface.[28]

When present in adult salamanders, lungs vary greatly among different species in size and structure. In aquatic, cold-water species like the torrent salamanders (Rhyacotriton), the lungs are very small with smooth walls, while species living in warm water with little dissolved oxygen, such as the lesser siren (Siren intermedia), have large lungs with convoluted surfaces. In the lungless salamanders (family Plethodontidae and the clawed salamanders in the family of Asiatic salamanders), no lungs or gills are present, and gas exchange mostly takes place through the skin, known as cutaneous respiration, supplemented by the tissues lining the mouth. To facilitate this, these salamanders have a dense network of blood vessels just under the skin and in the mouth.[28][29][30]

In the amphiumas, metamorphosis is incomplete, and they retain one pair of gill slits as adults, with fully functioning internal lungs.[31] Some species that lack lungs respire through gills. In most cases, these are external gills, visible as tufts on either side of the head. Some terrestrial salamanders have lungs used in respiration, although these are simple and sac-like, unlike the more complex organs found in mammals. Many species, such as the olm, have both lungs and gills as adults.[7]

A dissected view of the levatores arcuum muscles in a Necturus maculosus specimen. These (shown in the purple circles) move the external gills, as a means of respiration.

In the Necturus, external gills begin to form as a means of combating hypoxia in the egg as egg yolk is converted into metabolically active tissue.[32] However, molecular changes in the mudpuppy during post-embryonic development primarily due to the thyroid gland prevent the internalization of the external gills as seen in most salamanders that undergo metamorphosis.[33] The external gills seen in salamanders differs greatly from that of amphibians with internalized gills. Unlike amphibians with internalized gills which typically rely on the changing of pressures within the buccal and pharyngeal cavities to ensure diffusion of oxygen onto the gill curtain, neotenic salamanders such as Necturus use specified musculature, such as the levatores arcuum, to move external gills to keep the respiratory surfaces constantly in contact with new oxygenated water.[34][35]

Feeding and diet

Salamanders are opportunistic predators. They are generally not restricted to specific foods, but feed on almost any organism of a reasonable size.[36] Large species such as the Japanese giant salamander (Andrias japonicus) eat crabs, fish, small mammals, amphibians, and aquatic insects.[37] In a study of smaller dusky salamanders (Desmognathus) in the Appalachian Mountains, their diet includes earthworms, flies, beetles, beetle larvae, leafhoppers, springtails, moths, spiders, grasshoppers, and mites.[36] Cannibalism sometimes takes place, especially when resources are short or time is limited. Tiger salamander tadpoles in ephemeral pools sometimes resort to eating each other, and are seemingly able to target unrelated individuals.[38] Adult blackbelly salamanders (Desmognathus quadramaculatus) prey on adults and young of other species of salamanders, while their larvae sometimes cannibalise smaller larvae.[39]

The head of a tiger salamander

Most species of salamander have small teeth in both their upper and lower jaws. Unlike frogs, even the larvae of salamanders possess these teeth.[7] Although larval teeth are shaped like pointed cones, the teeth of adults are adapted to enable them to readily grasp prey. The crown, which has two cusps (bicuspid), is attached to a pedicel by collagenous fibers. The joint formed between the bicuspid and the pedicel is partially flexible, as it can bend inward, but not outward. When struggling prey is advanced into the salamander's mouth, the teeth tips relax and bend in the same direction, encouraging movement toward the throat, and resisting the prey's escape.[40] Many salamanders have patches of teeth attached to the vomer and the palatine bones in the roof of the mouth, and these help to retain prey. All types of teeth are resorbed and replaced at intervals throughout the animal's life.[41]

A terrestrial salamander catches its prey by flicking out its sticky tongue in an action that takes less than half a second. In some species, the tongue is attached anteriorly to the floor of the mouth, while in others, it is mounted on a pedicel. It is rendered sticky by secretions of mucus from glands in its tip and on the roof of the mouth.[42] High-speed cinematography shows how the tiger salamander (Ambystoma tigrinum) positions itself with its snout close to its prey. Its mouth then gapes widely, the lower jaw remains stationary, and the tongue bulges and changes shape as it shoots forward. The protruded tongue has a central depression, and the rim of this collapses inward as the target is struck, trapping the prey in a mucus-laden trough. Here it is held while the animal's neck is flexed, the tongue retracted and jaws closed. Large or resistant prey is retained by the teeth while repeated protrusions and retractions of the tongue draw it in. Swallowing involves alternate contraction and relaxation of muscles in the throat, assisted by depression of the eyeballs into the roof of the mouth.[43] Many lungless salamanders of the family Plethodontidae have more elaborate feeding methods. Muscles surrounding the hyoid bone contract to store elastic energy in springy connective tissue, and actually "shoot" the hyoid bone out of the mouth, thus elongating the tongue.[44][45] Muscles that originate in the pelvic region and insert in the tongue are used to reel the tongue and the hyoid back to their original positions.[46]

An aquatic salamander lacks muscles in the tongue, and captures its prey in an entirely different manner. It grabs the food item, grasps it with its teeth, and adopts a kind of inertial feeding. This involves tossing its head about, drawing water sharply in and out of its mouth, and snapping its jaws, all of which tend to tear and macerate the prey, which is then swallowed.[46]

Though frequently feeding on slow-moving animals like snails, shrimps and worms, sirenids are unique among salamanders for having developed speciations towards herbivory, such as beak-like jaw ends and extensive intestines. They feed on algae and other soft-plants in the wild, and easily eat offered lettuce.[47]

Defense

Further information: Antipredator adaptations

Salamanders have thin skins and soft bodies, and move rather slowly, and at first sight might appear to be vulnerable to opportunistic predation. However, they have several effective lines of defense. Mucus coating on damp skin makes them difficult to grasp, and the slimy coating may have an offensive taste or be toxic. When attacked by a predator, a salamander may position itself to make the main poison glands face the aggressor. Often, these are on the tail, which may be waggled or turned up and arched over the animal's back. The sacrifice of the tail may be a worthwhile strategy, if the salamander escapes with its life and the predator learns to avoid that species of salamander in the future.[48]

Aposematism

Further information: aposematism
A fire salamander's striking black and yellow pattern warns off predators

Skin secretions of the tiger salamander (Ambystoma tigrinum) fed to rats have been shown to produce aversion to the flavor, and the rats avoided the presentational medium when it was offered to them again.[49] The fire salamander (Salamandra salamandra) has a ridge of large granular glands down its spine which are able to squirt a fine jet of toxic fluid at its attacker. By angling its body appropriately, it can accurately direct the spray for a distance of up to 80 cm (30 in).[50]

The Iberian ribbed newt (Pleurodeles waltl) has another method of deterring aggressors. Its skin exudes a poisonous, viscous fluid and at the same time, the newt rotates its sharply pointed ribs through an angle between 27 and 92°, and adopts an inflated posture. This action causes the ribs to puncture the body wall, each rib protruding through an orange wart arranged in a lateral row. This may provide an aposematic signal that makes the spines more visible. When the danger has passed, the ribs retract and the skin heals.[51]

Camouflage and mimicry

Further information: camouflage and mimicry

Although many salamanders have cryptic colors so as to be unnoticeable, others signal their toxicity by their vivid coloring. Yellow, orange, and red are the colors generally used, often with black for greater contrast. Sometimes, the animal postures if attacked, revealing a flash of warning hue on its underside. The red eft, the brightly colored terrestrial juvenile form of the eastern newt (Notophthalmus viridescens), is highly poisonous. It is avoided by birds and snakes, and can survive for up to 30 minutes after being swallowed (later being regurgitated).[52] The red salamander (Pseudotriton ruber) is a palatable species with a similar coloring to the red eft. Predators that previously fed on it have been shown to avoid it after encountering red efts, an example of Batesian mimicry.[52] Other species exhibit similar mimicry. In California, the palatable yellow-eyed salamander (Ensatina eschscholtzii) closely resembles the toxic California newt (Taricha torosa) and the rough-skinned newt (Taricha granulosa), whereas in other parts of its range, it is cryptically colored.[53] A correlation exists between the toxicity of Californian salamander species and diurnal habits: relatively harmless species like the California slender salamander (Batrachoseps attenuatus) are nocturnal and are eaten by snakes, while the California newt has many large poison glands in its skin, is diurnal, and is avoided by snakes.[54]

Autotomy

Further information: autotomy

Some salamander species use tail autotomy to escape predators. The tail drops off and wriggles around for a while after an attack, and the salamander either runs away or stays still enough not to be noticed while the predator is distracted. The tail regrows with time, and salamanders routinely regenerate other complex tissues, including the lens or retina of the eye. Within only a few weeks of losing a piece of a limb, a salamander perfectly reforms the missing structure.[55]

Distribution and habitat

Salamanders split off from the other amphibians during the mid- to late Permian, and initially were similar to modern members of the Cryptobranchoidea. Their resemblance to lizards is the result of symplesiomorphy, their common retention of the primitive tetrapod body plan, but they are no more closely related to lizards than they are to mammals. Their nearest relatives are the frogs and toads, within Batrachia. The earliest known salamander fossils have been found in geological deposits in China and Kazakhstan, dated to the middle Jurassic period around 164 million years ago.[56]

Salamanders are found only in the Holarctic and Neotropical regions, not reaching south of the Mediterranean Basin, the Himalayas, or in South America the Amazon Basin. They do not extend north of the Arctic tree line, with the northernmost Asian species, Salamandrella keyserlingii, which can survive long-term freezing at −55 °C,[57] occurring in the Siberian larch forests of Sakha and the most northerly species in North America, Ambystoma laterale, reaching no farther north than Labrador and Taricha granulosa not beyond the Alaska Panhandle.[58] They had an exclusively Laurasian distribution until Bolitoglossa invaded South America from Central America, probably by the start of the Early Miocene, about 23 million years ago.[59] They also lived on the Caribbean Islands during the early Miocene epoch, confirmed by the discovery of Palaeoplethodon hispaniolae,[60] found trapped in amber in the Dominican Republic. However, possible salamander fossils have been found in Australia at the Murgon fossil site, representing the only known salamanders known from the continent.[61]

There are about 760 living species of salamander.[62][63] One-third of the known salamander species are found in North America. The highest concentration of these is found in the Appalachian Mountains region, where the Plethodontidae are thought to have originated in mountain streams. Here, vegetation zones and proximity to water are of greater importance than altitude. Only species that adopted a more terrestrial mode of life have been able to disperse to other localities. The northern slimy salamander (Plethodon glutinosus) has a wide range and occupies a habitat similar to that of the southern gray-cheeked salamander (Plethodon metcalfi). The latter is restricted to the slightly cooler and wetter conditions in north-facing cove forests in the southern Appalachians, and to higher elevations above 900 m (3,000 ft), while the former is more adaptable, and would be perfectly able to inhabit these locations, but some unknown factor seems to prevent the two species from co-existing.[36]

One species, the Anderson's salamander, is one of the few species of living amphibians to occur in brackish or salt water.[64]

Reproduction and development

See also: Sexual selection in amphibians
Sierra newt amplexus found in stream at Woolman Semester in Nevada County, California

Many salamanders do not use vocalisations,[65] and in most species the sexes look alike, so they use olfactory and tactile cues to identify potential mates, and sexual selection occurs. Pheromones play an important part in the process and may be produced by the abdominal gland in males and by the cloacal glands and skin in both sexes. Males are sometimes to be seen investigating potential mates with their snouts. In Old World newts, Triturus spp., the males are sexually dimorphic and display in front of the females. Visual cues are also thought to be important in some Plethodont species.[66]

Except for terrestrial species in the three families Plethodontidae, Ambystomatidae, and Salamandridae, salamanders mate in water.[67] The mating varies from courtship between a single male and female to explosive group breeding.[68] In the clade Salamandroidea, which makes up about 90% of all species, fertilization is internal.[69] As a general rule, salamanders with internal fertilization have indirect sperm transfer, but in species like the Sardinian brook salamander, the Corsican brook salamander, the Caucasian salamander and the Pyrenean brook salamander, the male transfer his sperm directly into the female cloaca.[70][71][72] For the species with indirect sperm transfer, the male deposits a spermatophore on the ground or in the water according to species, and the female picks this up with her vent. The spermatophore has a packet of sperm supported on a conical gelatinous base, and often an elaborate courtship behavior is involved in its deposition and collection. Once inside the cloaca, the spermatozoa move to the spermatheca, one or more chambers in the roof of the cloaca, where they are stored for sometimes lengthy periods until the eggs are laid. In the Asiatic salamanders, the giant salamanders and Sirenidae, which are the most primitive groups, the fertilization is external. In a reproductive process similar to that of typical frogs, the male releases sperm onto the egg mass. These salamanders also have males that exhibit parental care, which otherwise only occur in females with internal fertilization.[66][73]

Three different types of egg deposition occur. Ambystoma and Taricha spp. spawn large numbers of small eggs in quiet ponds where many large predators are unlikely. Most dusky salamanders (Desmognathus) and Pacific giant salamanders (Dicamptodon) lay smaller batches of medium-sized eggs in a concealed site in flowing water, and these are usually guarded by an adult, normally the female. Many of the tropical climbing salamanders (Bolitoglossa) and lungless salamanders (Plethodontinae) lay a small number of large eggs on land in a well-hidden spot, where they are also guarded by the mother.[66] Some species such as the fire salamanders (Salamandra) are ovoviviparous, with the female retaining the eggs inside her body until they hatch, either into larvae to be deposited in a water body, or into fully formed juveniles.[7]

Embryonic development of a salamander, filmed in the 1920s

In temperate regions, reproduction is usually seasonal and salamanders may migrate to breeding grounds. Males usually arrive first and in some instances set up territories. Typically, a larval stage follows in which the organism is fully aquatic. The tadpole has three pairs of external gills, no eyelids, a long body, a laterally flattened tail with dorsal and ventral fins and in some species limb-buds or limbs. Pond-type larvae may have a pair of rod-like balancers on either side of the head, long gill filaments and broad fins. Stream-type larvae are more slender with short gill filaments—in Rhyacotriton and Onychodactylus, and some species in Batrachuperus, the gills and gill rakers are extremely reduced,[74] narrower fins and no balancers, but instead have hind limbs already developed when they hatch.[75] The tadpoles are carnivorous and the larval stage may last from days to years, depending on species. Sometimes this stage is completely bypassed, and the eggs of most lungless salamanders (Plethodontidae) develop directly into miniature versions of the adult without an intervening larval stage.[76]

By the end of the larval stage, the tadpoles already have limbs and metamorphosis takes place normally. In salamanders, this occurs over a short period of time and involves the closing of the gill slits and the loss of structures such as gills and tail fins that are not required as adults. At the same time, eyelids develop, the mouth becomes wider, a tongue appears, and teeth are formed. The aqueous larva emerges onto land as a terrestrial adult.[77]

Neotenic axolotl, showing external gills

Not all species of salamanders follow this path. Neoteny, also known as paedomorphosis, has been observed in all salamander families, and may be universally possible in all salamander species. In this state, an individual may retain gills or other juvenile features while attaining reproductive maturity. The changes that take place at metamorphosis are under the control of thyroid hormones and in obligate neotenes such as the axolotl (Ambystoma mexicanum), the tissues are seemingly unresponsive to the hormones. In other species, the changes may not be triggered because of underactivity of the hypothalamus-pituitary-thyroid mechanism which may occur when conditions in the terrestrial environment are too inhospitable.[77] This may be due to cold or wildly fluctuating temperatures, aridity, lack of food, lack of cover, or insufficient iodine for the formation of thyroid hormones. Genetics may also play a part. The larvae of tiger salamanders (Ambystoma tigrinum), for example, develop limbs soon after hatching and in seasonal pools promptly undergo metamorphosis. Other larvae, especially in permanent pools and warmer climates, may not undergo metamorphosis until fully adult in size. Other populations in colder climates may not metamorphose at all, and become sexually mature while in their larval forms. Neoteny allows the species to survive even when the terrestrial environment is too harsh for the adults to thrive on land.[75]

Conservation

The threatened hellbender

A general decline in living amphibian species has been linked with the fungal disease chytridiomycosis. A higher proportion of salamander species than of frogs or caecilians are in one of the at-risk categories established by the IUCN. Salamanders showed a significant diminution in numbers in the last few decades of the 20th century, although no direct link between the fungus and the population decline has yet been found.[78] The IUCN made further efforts in 2005 as they established the Amphibian Conservation Action Plan (ACAP), which was subsequently followed by Amphibian Ark (AArk), Amphibian Specialist Group (ASG), and finally the umbrella organization known as the Amphibian Survival Alliance (ASA).[79] Researchers also cite deforestation, resulting in fragmentation of suitable habitats, and climate change as possible contributory factors. Species such as Pseudoeurycea brunnata and Pseudoeurycea goebeli that had been abundant in the cloud forests of Guatemala and Mexico during the 1970s were found by 2009 to be rare.[80] However, few data have been gathered on population sizes over the years, and by intensive surveying of historic and suitable new locations, it has been possible to locate individuals of other species such as Parvimolge townsendi, which had been thought to be extinct.[78] Currently, the major lines of defense for the conservation of Salamanders includes both in situ and ex situ conservation methods. There are efforts in place for certain members of the Salamander family to be conserved under a conservation breeding program (CBP) but it is important to note that there should be research done ahead of time to determine if the Salamander species is actually going to value from the CBP, as researchers have noted that some species of amphibians completely fail in this environment.[79]

Various conservation initiatives are being attempted around the world. The Chinese giant salamander, at 1.8 m (6 ft) the largest amphibian in the world, is critically endangered, as it is collected for food and for use in traditional Chinese medicine. An environmental education programme is being undertaken to encourage sustainable management of wild populations in the Qinling Mountains and captive breeding programmes have been set up.[81] The hellbender is another large, long-lived species with dwindling numbers and fewer juveniles reaching maturity than previously.[82] Another alarming finding is the increase in abnormalities in up to 90% of the hellbender population in the Spring River watershed in Arkansas.[83] Habitat loss, silting of streams, pollution and disease have all been implicated in the decline and a captive breeding programme at Saint Louis Zoo has been successfully established.[84] Of the 20 species of minute salamanders (Thorius spp.) in Mexico, half are believed to have become extinct and most of the others are critically endangered. Specific reasons for the decline may include climate change, chytridiomycosis, or volcanic activity, but the main threat is habitat destruction as logging, agricultural activities, and human settlement reduce their often tiny, fragmented ranges. Survey work is being undertaken to assess the status of these salamanders, and to better understand the factors involved in their population declines, with a view to taking action.[85]

Ambystoma mexicanum, an aquatic salamander, is a species protected under the Mexican UMA (Unit for Management and conservation of wildlife) as of April 1994. Another detrimental factor is that the axolotl lost their role as a top predator since the introduction of locally exotic species such as Nile tilapia and carp. Tilapia and carp directly compete with axolotls by consuming their eggs, larvae, and juveniles. Climate change has also immensely affected axolotls and their populations throughout the southern Mexico area. Due to its proximity to Mexico City, officials are currently working on programs at Lake Xochimilco to bring in tourism and educate the local population on the restoration of the natural habitat of these creatures.[86] This proximity is a large factor that has impacted the survival of the axolotl, as the city has expanded to take over the Xochimilco region in order to make use of its resources for water and provision and sewage.[87] However, the axolotl has the benefit of being raised in farms for the purpose of research facilities. So there is still a chance that they may be able to return to their natural habitat. The recent decline in population has substantially impacted genetic diversity among populations of axolotl, making it difficult to further progress scientifically. It is important to note that although there is a level of limited genetic diversity due to Ambystoma populations, such as the axolotl, being paedeomorphic species, it does not account for the overall lack of diversity. There is evidence that points towards a historical bottlenecking of Ambystoma that contributes to the variation issues. Unfortunately, there is no large genetic pool for the species to pull from unlike in historical times. Thus there is severe concern for inbreeding due to lack of gene flow.[88] One way researchers are looking into maintaining genetic diversity within the population is via cryopreservation of the spermatophores from the male axolotl. It is a safe and non-invasive method that requires the collection of the spermatophores and places them into a deep freeze for preservation. Most importantly, they have found that there is only limited damage done to the spermatophores upon thawing and thus it is a viable option. As of 2013, it is a method that is being used to save not only the axolotl but also numerous other members of the salamander family.[87][89][90]

Research is being done on the environmental cues that have to be replicated before captive animals can be persuaded to breed. Common species such as the tiger salamander and the mudpuppy are being given hormones to stimulate the production of sperm and eggs, and the role of arginine vasotocin in courtship behaviour is being investigated. Another line of research is artificial insemination, either in vitro or by inserting spermatophores into the cloacae of females. The results of this research may be used in captive-breeding programmes for endangered species.[91]

Taxonomy

The order name Urodela comes from the name Urodèles given by André Marie Constant Duméril in 1805,[2] it is derived from the Greek words οὐρά ourā́ "tail" and δῆλος dēlos "visible, conspicuous" because of their "persistent" tails.[92]

Disagreement exists among different authorities as to the definition of the terms Caudata and Urodela. Some maintain that the Urodela should be restricted to the crown group, with the Caudata being used for the total group.[2][citation needed] Others restrict the name Caudata to the crown group and use Urodela for the total group.[93][94] The former approach seems to be most widely adopted and is used in this article.[63]

The ten families belonging to Urodela are divided into three suborders.[93] The clade Neocaudata is often used to separate the Cryptobranchoidea and Salamandroidea from the Sirenoidea.

Cryptobranchoidea (Giant salamanders)
Family Common names Example species

Example image

Cryptobranchidae Giant salamanders Hellbender (Cryptobranchus alleganiensis)
Hynobiidae Asiatic salamanders Hida salamander (Hynobius kimurae)
Salamandroidea (Advanced salamanders)
Ambystomatidae Mole salamanders Marbled salamander (Ambystoma opacum)
Amphiumidae Amphiumas or Congo eels Two-toed amphiuma (Amphiuma means)
Plethodontidae Lungless salamanders Red-backed salamander (Plethodon cinereus)
Proteidae Mudpuppies and olms Olm (Proteus anguinus)
Rhyacotritonidae Torrent salamanders Southern torrent salamander (Rhyacotriton variegatus)
Salamandridae Newts and true salamanders Alpine newt (Ichthyosaura alpestris)
Sirenoidea (Sirens)
Sirenidae Sirens Greater siren (Siren lacertina)

Phylogeny and evolution

The origins and evolutionary relationships between the three main groups of amphibians (gymnophionans, urodeles and anurans) is a matter of debate. A 2005 molecular phylogeny, based on rDNA analysis, suggested that the first divergence between these three groups took place soon after they had branched from the lobe-finned fish in the Devonian (around 360 million years ago), and before the breakup of the supercontinent Pangaea. The briefness of this period, and the speed at which radiation took place, may help to account for the relative scarcity of amphibian fossils that appear to be closely related to lissamphibians.[95] However, more recent studies have generally found more recent (Late Carboniferous[96] to Permian[97]) age for the basalmost divergence among lissamphibians.

Karaurus sharovi

The earliest known salamander-line lissamphibian is Triassurus from the Middle-Late Triassic of Kyrgyzstan.[98] Other fossil salamanders are known from the Middle-Late Jurassic of Eurasia, including Kokartus honorarius from the Middle Jurassic of Kyrgyzstan, two species of the apparently neotenic, aquatic Marmorerpeton from the Middle Jurassic of England and Scotland,[99] and Karaurus from the Middle-Late Jurassic of Kazakhstan, resembled modern mole salamanders in morphology and probably had a similar burrowing lifestyle.[63] They looked like robust modern salamanders but lacked a number of anatomical features that characterise all modern salamanders.[100]

The two groups of extant salamanders are the Cryptobranchoidea (which includes Asiatic and giant salamanders) and the Salamandroidea (which includes all other living salamanders), also known as Diadectosalamandroidei. Both groups are known from the Middle-Late Jurassic of China. the former being exemplified by Chunerpeton tianyiensis, Pangerpeton sinensis, Jeholotriton paradoxus, Regalerpeton weichangensis, Liaoxitriton daohugouensis and Iridotriton hechti, and the latter by Beiyanerpeton jianpingensis. By the Upper Cretaceous, most or all of the living salamander families had probably appeared.[63]

The following cladogram shows the relationships between salamander families based on the molecular analysis of Pyron and Wiens (2011).[101] The position of the Sirenidae is disputed, but the position as sister to the Salamandroidea best fits with the molecular and fossil evidence.[63]

Cryptobranchoidea

Cryptobranchidae (giant salamanders & hellbenders)

Hynobiidae (Asiatic salamanders)

Sirenoidea

Sirenidae (sirens)

Salamandroidea
Treptobranchia

Salamandridae (true salamanders & newts)

Ambystomatidae (axolotls & tiger salamanders)

Dicamptodontidae (Pacific giant salamanders)

Proteidae (olms & waterdogs)

Plethosalamandroidei

Rhyacotritonidae (torrent salamanders)

Xenosalamandroidei

Amphiumidae (amphiumas)

Plethodontidae (lungless salamanders)

Genome and genetics

Salamanders possess gigantic genomes, spanning the range from 14 Gb to 120 Gb[102] (the human genome is 3.2 Gb long). The genomes of Pleurodeles waltl (20 Gb) and Ambystoma mexicanum (32 Gb) have been sequenced.[103][104]

Their giant genomes have strongly affected their physiology. This includes their skeletal and circulatory systems, and have led to a simplified brain, weak heart and slow metabolism.[105] The cell mechanisms that prevents transposons to accumulate seems to be partially defect in salamanders. Some species with the largest genomes have lost the ability to go through metamorphosis. The development of the body is slower than its growth compared to their ancestors, and stops at a certain age, leaving them with embryonic traits. The salamander tissues contain cells that differentiates slowly, weakly, or not at all, due to intron delay, which gives them regenerative properties, which includes regenerating parts of the face and eye, lungs, liver, heart, and even the spinal cord and brain, and they have been described as “walking bags of stem cells.”[106][107][108] Research has also shown that they do not develop typical signs of aging and do not accumulate age-related diseases like cancer.[109]

In human society

Myth and legend

Main article: Cultural depictions of salamanders
A salamander unharmed in the fire, 1350

Legends have developed around the salamander over the centuries, many related to fire. This connection likely originates from the tendency of many salamanders to dwell inside rotting logs. When the log was placed into a fire, the salamander would attempt to escape, lending credence to the belief that salamanders were created from flames.[110]

The association of the salamander with fire appeared first in Antiquity with Aristotle (History of Animals 5, 17) and with Pliny the Elder writing in his Natural History (10, 86) that "A salamander is so cold that it puts out fire on contact. It vomits from its mouth a milky liquid; if this liquid touches any part of the human body it causes all the hair to fall off, and the skin to change color and break out in a rash."[111] The ability to put out fire is repeated by Saint Augustine in the fifth century and Isidore of Seville in the seventh century.[112][113]

Ukiyo-e print by Utagawa Kuniyoshi (1797–1861) depicting a giant salamander being stabbed by the samurai Hanagami Danjō no jō Arakage

The mythical ruler Prester John supposedly had a robe made from alleged salamander hair, in fact asbestos fibre, already known by ancient Greece and Rome (the linum vivum of Pliny the Elder Naturalis historia, 19, 4).[114] The "Emperor of India" possessed a suit made from a thousand skins; Pope Alexander III had a tunic which he valued highly and William Caxton (1481) wrote: "This Salemandre berithe wulle, of which is made cloth and gyrdles that may not brenne in the fyre."[115] The salamander was said to be so toxic that by twining around a tree, it could poison the fruit and so kill any who ate them and by falling into a well, could kill all who drank from it.[115]

In his autobiography, Benvenuto Cellini relates:

When I was about five, my father was sitting alone in one of our small rooms, singing and playing his viol. Some washing had just been done there and a good log fire was still burning. It was very cold, and he had drawn near the fire. Then, as he was looking at the flames, his eye fell on a little animal, like a lizard, that was running around merrily in the very hottest part of the fire. Suddenly realizing what it was, he called my sister and myself and showed it to us. And then he gave me such a violent box on the ears that I screamed and burst into tears. At this he calmed me as kindly as he could and said: 'My dear little boy, I didn't hit you because you had done wrong. I only did it so that you will never forget that the lizard you saw in the fire is a salamander, and as far as we know for certain no one has ever seen one before.'[116]

The Japanese giant salamander has been the subject of legend and artwork in Japan (e.g. the ukiyo-e work by Utagawa Kuniyoshi). The well-known Japanese mythological creature known as the kappa may be inspired by this salamander.[117]

Medical reseach

Salamanders' limb regeneration has long been the focus of interest among scientists. The first extensive cell-level study was by Vincenzo Colucci in 1886.[118] Researchers have been trying to find out the conditions required for the growth of new limbs and hope that such regeneration could be replicated in humans using stem cells. Axolotls have been used in research and have been genetically engineered so that a fluorescent protein is present in cells in the leg, enabling the cell division process to be tracked under the microscope. It seems that after the loss of a limb, cells draw together to form a clump known as a blastema. This superficially appears undifferentiated, but cells that originated in the skin later develop into new skin, muscle cells into new muscle and cartilage cells into new cartilage. It is only the cells from just beneath the surface of the skin that are pluripotent and able to develop into any type of cell.[119] Researchers from the Australian Regenerative Medicine Institute have found that when macrophages were removed, salamanders lost their ability to regenerate and instead formed scar tissue. If the processes involved in forming new tissue can be reverse engineered into humans, it may be possible to heal injuries of the spinal cord or brain, repair damaged organs and reduce scarring and fibrosis after surgery.[120]

The spotted salamander (Amblystoma maculatum) lives in a symbiotic relationship with a green algae known as Oophila amblystomatis. The algal cells make their way into tissue cells throughout the embryo's body and appears to avoid rejection by activating genes which suppress the embryo's immune response. A mechanism that could be used in treatment for autoimmune diseases in humans.[121]

Brandy

A 1995 article in the Slovenian weekly magazine Mladina publicized salamander brandy, a liquor supposedly indigenous to Slovenia. It was said to combine hallucinogenic with aphrodisiac effects and is made by putting several live salamanders in a barrel of fermenting fruit. Stimulated by the alcohol, they secrete toxic mucus in defense and eventually die. Besides causing hallucinations, the neurotoxins present in the brew were said to cause extreme sexual arousal.[122]

Later research by Slovenian anthropologist Miha Kozorog (University of Ljubljana) paints a very different picture—Salamander in brandy appears to have been traditionally seen as an adulterant, one which caused ill health. It was also used as a term of slander.[123]

References

Citations

  1. ^ Anderson, J. S. (2012). "Fossils, molecules, divergence times, and the origin of Salamandroidea". Proceedings of the National Academy of Sciences. 109 (15): 5557–5558. Bibcode:2012PNAS..109.5557A. doi:10.1073/pnas.1202491109. PMC 3326514. PMID 22460794.
  2. ^ a b c Frost, Darrel R. (2023) [1998]. "Caudata". Amphibian Species of the World. American Museum of Natural History. Archived from the original on 22 March 2023. Retrieved 22 March 2023.
  3. ^ "Missing Parts? Salamander Regeneration Secret Revealed". Live Science. 20 May 2013. Archived from the original on 16 July 2018. Retrieved 15 July 2018.
  4. ^ Zhong, Jixing; Aires, Rita; Tsissios, Georgios; Skoufa, Evangelia; Brandt, Kerstin; Sandoval-Guzmán, Tatiana; Aztekin, Can (10 October 2023). "Multi-species atlas resolves an axolotl limb development and regeneration paradox". Nature Communications. 14 (1): 6346. Bibcode:2023NatCo..14.6346Z. doi:10.1038/s41467-023-41944-w. PMC 10564727. PMID 37816738.
  5. ^ Harper, Douglas. "salamander". Online Etymology Dictionary. Retrieved 22 March 2023.
  6. ^ Liddell, Henry George; Scott, Robert (1940). "σαλαμάνδρα". A Greek-English Lexicon. Perseus Digital Library. Archived from the original on 2023-03-12. Retrieved 2023-03-22.
  7. ^ a b c d e f Lanza, B.; Vanni, S.; Nistri, A. (1998). Cogger, H. G.; Zweifel, R. G. (eds.). Encyclopedia of Reptiles and Amphibians. Academic Press. pp. 60–68. ISBN 978-0-12-178560-4.
  8. ^ Metabolism, gas exchange, and acid-base balance of giant salamanders
  9. ^ Field Guide to Amphibians and Reptiles of California: Revised Edition
  10. ^ Stebbins & Cohen (1995) p. 3
  11. ^ Lopez, Carl H.; Brodie, Edmund D. Jr. (1972). "The Function of Costal Grooves in Salamanders (Amphibia, Urodela)". Journal of Herpetology. 11 (3): 372–374. doi:10.2307/1563252. JSTOR 1563252.
  12. ^ a b c Stebbins & Cohen (1995) pp. 26–30
  13. ^ a b Stebbins & Cohen (1995) pp. 10–16
  14. ^ Brodie, Edmund D. Jr. (1968). "Investigations on the skin toxin of the adult rough-skinned newt, Taricha granulosa". Copeia. 1968 (2): 307–313. doi:10.2307/1441757. JSTOR 1441757. S2CID 52235877.
  15. ^ a b Wells, Kentwood, D. (2010). The Ecology and Behavior of Amphibians. University of Chicago Press. pp. 411–417. ISBN 978-0-226-89333-4.((cite book)): CS1 maint: multiple names: authors list (link)
  16. ^ León, Ezequiel González; Ramírez-Pinilla, Martha Patricia (2009). "The mental gland of Bolitoglossa nicefori (Caudata: Plethodontidae)". Amphibia-Reptilia. 30 (4): 561–569. doi:10.1163/156853809789647013.
  17. ^ Stebbins & Cohen (1995) pp. 37–40
  18. ^ Stebbins & Cohen (1995) pp. 42–44
  19. ^ Przyrembel, C.; Keller, B.; Neumeyer, C. (1995). "Trichromatic color vision in the salamander (Salamandra salamandra)". Journal of Comparative Physiology. 176 (4): 575–586. doi:10.1007/BF00196422. S2CID 749622.
  20. ^ Schoch, Rainer R. (19 March 2014). Amphibian Evolution: The Life of Early Land Vertebrates. John Wiley & Sons. ISBN 9781118759134. Retrieved 15 July 2018 – via Google Books.
  21. ^ "Researchers reveal how hearing evolved". sciencedaily.com. Archived from the original on 16 July 2018. Retrieved 15 July 2018.
  22. ^ Becker, R. P.; Lombard, R. E. (1977). "Structural correlates of function in the "opercularis" muscle of amphibians". Cell and Tissue Research. 175 (4): 499–522. doi:10.1007/bf00222415. PMID 830429. S2CID 25650919.
  23. ^ Stebbins & Cohen (1995) pp. 69–72
  24. ^ Underwater sound production varies within not between species in sympatric newts
  25. ^ Vertebrate Biology: Systematics, Taxonomy, Natural History, and Conservation
  26. ^ Hubáček, J.; Šugerková, M.; Gvoždík, L. (2019). "Underwater sound production varies within not between species in sympatric newts". PeerJ. 7: e6649. doi:10.7717/peerj.6649. PMC 6441559. PMID 30944780.
  27. ^ Stebbins & Cohen (1995) pp. 76–77
  28. ^ a b Stebbins & Cohen (1995) pp. 17–25
  29. ^ Cogger & Zweifel (1998), pp. 74–75.
  30. ^ Kakehashi, Ryosuke; Kurabayashi, Atsushi (2021). "Patterns of Natural Selection on Mitochondrial Protein-Coding Genes in Lungless Salamanders: Relaxed Purifying Selection and Presence of Positively Selected Codon Sites in the Family Plethodontidae". International Journal of Genomics. 2021: 1–12. doi:10.1155/2021/6671300. PMC 8053045. PMID 33928143.
  31. ^ Toews, Daniel P. (1974). "Respiratory Mechanisms in the Aquatic Salamander, Amphiuma tridactylum". Copeia. 1974 (4): 917–920. doi:10.2307/1442591. JSTOR 1442591.
  32. ^ Rogge, Jessica R.; Warkentin, Karen M. (2008-11-15). "External gills and adaptive embryo behavior facilitate synchronous development and hatching plasticity under respiratory constraint". Journal of Experimental Biology. 211 (22): 3627–3635. doi:10.1242/jeb.020958. ISSN 0022-0949. PMID 18978228.
  33. ^ Duellman, William Edward (1994). Biology of Amphibians. The Johns Hopkins University Press.
  34. ^ V., Kardong, Kenneth (2012). Vertebrates : comparative anatomy, function, evolution. McGraw-Hill. ISBN 9780073524238. OCLC 939087630.((cite book)): CS1 maint: multiple names: authors list (link)
  35. ^ Zalisko, Edward J. (2015). Comparative vertebrate anatomy a laboratory dissection guide. McGraw-Hill Education. ISBN 9780077657055. OCLC 935173274.
  36. ^ a b c Hairston, Nelson G. (1949). "The local distribution and ecology of the plethodontid salamanders of the southern Appalachians". Ecological Monographs. 19 (1): 47–73. Bibcode:1949EcoM...19...47H. doi:10.2307/1943584. JSTOR 1943584.
  37. ^ "Plethodontidae". AmphibiaWeb. Archived from the original on 2014-02-22. Retrieved 2014-02-09.
  38. ^ Koppes, Steve (2009-09-24). "He ain't tasty, he's my brother". Ask a Biologist. Arizona State University. Archived from the original on 2014-02-22. Retrieved 2014-02-08.
  39. ^ "Desmognathus quadramaculatus". AmphibiaWeb. Archived from the original on 2014-02-22. Retrieved 2014-02-09.
  40. ^ Kardong (2009), pp. 505–506.
  41. ^ Stebbins & Cohen (1995) pp. 57–58
  42. ^ Stebbins & Cohen (1995) pp. 58–60
  43. ^ Larsen, John H. jr.; Guthrie, Dan J. (1975). "The feeding system of terrestrial tiger salamanders (Ambystoma tigrinum melanostictum baird)". Journal of Morphology. 147 (2): 137–153. doi:10.1002/jmor.1051470203. PMID 30309060. S2CID 52959566.
  44. ^ Deban, S.M.; Wake, D.B.; Roth, G. (1997). "Salamander with a ballistic tongue". Nature. 389 (6646): 27–28. Bibcode:1997Natur.389...27D. doi:10.1038/37898. S2CID 205026166.
  45. ^ Deban, S. M.; O'Reilly, U. Dicke (2007). "Extremely high-power tongue projection in plethodontid salamanders". Journal of Experimental Biology. 210 (4): 655–667. doi:10.1242/jeb.02664. PMID 17267651.
  46. ^ a b Regal, Philip J. (1966). "Feeding specializations and the classification of terrestrial salamanders". Evolution. 20 (3): 392–407. doi:10.2307/2406638. JSTOR 2406638. PMID 28562974.
  47. ^ Hill, R. L.; Mendelson, J. R.; Stabile, J. L. (2015). "Direct observation and review of herbivory in Sirenidae (Amphibia: Caudata)". Southeastern Naturalist. 14: N5–N9. doi:10.1656/058.014.0104. S2CID 86233204.
  48. ^ Stebbins & Cohen (1995) pp. 110–120
  49. ^ Mason, J. Russell; Rabin, Michael D.; Stevens, David A. (1982). "Conditioned taste aversions: skin secretions used for defense by tiger salamanders, Ambystoma tigrinum". Copeia. 1982 (3): 667–671. doi:10.2307/1444668. JSTOR 1444668.
  50. ^ Brodie, Edmund D. Jr.; Smatresk, Neal J. (1990). "The antipredator arsenal of fire salamanders: spraying of secretions from highly pressurized dorsal skin glands". Herpetologica. 46 (1): 1–7. JSTOR 3892595.
  51. ^ Heiss, E.; Natchev, N.; Salaberger, D.; Gumpenberger, M.; Rabanser, A.; Weisgram, J. (2010). "Hurt yourself to hurt your enemy: new insights on the function of the bizarre antipredator mechanism in the salamandrid Pleurodeles waltl". Journal of Zoology. 280 (2): 156–162. doi:10.1111/j.1469-7998.2009.00631.x.
  52. ^ a b Howard, Ronnie R.; Brodie, Edmund D. Jr. (1973). "A Batesian mimetic complex in salamanders: responses of avian predators". Herpetologica. 29 (1): 33–41. JSTOR 3891196.
  53. ^ Kuchta, S. R.; Krakauer, A. H.; Sinervo, B (2008). "Why does the yellow-eyed ensatina have yellow eyes? Batesian mimicry of Pacific newts (genus Trachia) by the salamander Ensatina eschscholtzii xanthoptica". Evolution. 62 (4): 984–990. doi:10.1111/j.1558-5646.2008.00338.x. PMID 18248632. S2CID 998486.
  54. ^ Cott, 1940. Page 204.
  55. ^ Monaghan, James R.; Epp, Leonard G.; Putta, Srikrishna; Page, Robert B.; Walker, John A.; Beachy, Chris K.; Zhu, Wei; Pao, Gerald M.; Verma, Inder M.; Hunter, Tony; Bryant, Susan V.; Gardiner, David M.; Harkins, Tim T.; Voss, S. Randal (2009). "Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration". BMC Biology. 7 (1): 1. doi:10.1186/1741-7007-7-1. PMC 2630914. PMID 19144100.
  56. ^ Gao, Ke-Qin; Shubin, Neil H. (2012). "Late Jurassic salamandroid from western Liaoning, China". Proceedings of the National Academy of Sciences of the United States of America. 109 (15): 5767–5772. Bibcode:2012PNAS..109.5767G. doi:10.1073/pnas.1009828109. PMC 3326464. PMID 22411790.
  57. ^ Biochemical Response to Freezing in the Siberian Salamander Salamandrella keyserlingii
  58. ^ Wells, Kentwood D. (2007). The Ecology and Behavior of Amphibians. University of Chicago Press. p. 130. ISBN 978-0-226-89334-1.
  59. ^ Elmer, K. R.; Bonett, R. M.; Wake, D. B.; Lougheed, S. C. (2013-03-04). "Early Miocene origin and cryptic diversification of South American salamanders". BMC Evolutionary Biology. 13 (1): 59. Bibcode:2013BMCEE..13...59E. doi:10.1186/1471-2148-13-59. PMC 3602097. PMID 23497060.
  60. ^ "First-ever discovery of a salamander in amber sheds light on evolution of Caribbean islands | News and Research Communications | Oregon State University". oregonstate.edu. 2015-08-17. Archived from the original on 2017-02-19. Retrieved 2016-03-25.
  61. ^ Boles, W. E. (1997). "Fossil songbirds (Passeriformes) from the early Eocene of Australia". Emu. 97 (1): 43–50. Bibcode:1997EmuAO..97...43B. doi:10.1071/MU97004. ISSN 0158-4197.
  62. ^ "Species by number". AmphibiaWeb. Archived from the original on 2021-01-12. Retrieved 2021-01-11.
  63. ^ a b c d e Naish, Darren (2013-10-01). "The amazing world of salamanders". Scientific American. Archived from the original on 2014-01-16. Retrieved 2014-01-14.
  64. ^ Brad Shaffer; Oscar Flores-Villela; Gabriela Parra-Olea; David Wake (2004). "Ambystoma andersoni". IUCN Red List of Threatened Species. Version 2013.2. International Union for Conservation of Nature
  65. ^ Bradley, J. Gavin; Eason, Perri K. (2018). "Eurycea lucifuga (Cave Salamander) Vocalization". Herpetological Review. 49 (4): 725.((cite journal)): CS1 maint: multiple names: authors list (link)
  66. ^ a b c Stebbins & Cohen (1995) pp. 143–154
  67. ^ Buesching, Christina D. (19 July 2019). Chemical Signals in Vertebrates 14. Springer. ISBN 9783030176167.
  68. ^ "Examining the Influence of Mating Systems on Testes Size in Salamanders". Archived from the original on 2023-02-16. Retrieved 2023-02-16.
  69. ^ Jia, Jia; Anderson, Jason S.; Gao, Ke-Qin (2021). "Middle Jurassic stem hynobiids from China shed light on the evolution of basal salamanders". iScience. 24 (7). Bibcode:2021iSci...24j2744J. doi:10.1016/j.isci.2021.102744. PMC 8264161. PMID 34278256.
  70. ^ "Evolutionary reproductive morphology of amphibians" (PDF). Archived (PDF) from the original on 2023-03-07. Retrieved 2023-02-15.
  71. ^ Bovero, S.; Sotgiu, G.; Castellano, S.; Giacoma, C. (2003). "Age and Sexual Dimorphism in a Population of Euproctus platycephalus (Caudata: Salamandridae) from Sardinia". Copeia. 2003: 149–154. doi:10.1643/0045-8511(2003)003[0149:AASDIA]2.0.CO;2. S2CID 85909830.
  72. ^ Wells, Kentwood D. (15 February 2010). The Ecology and Behavior of Amphibians. University of Chicago Press. ISBN 9780226893334.
  73. ^ Vági, Balázs; Marsh, Daniel; Katona, Gergely; Végvári, Zsolt; Freckleton, Robert P.; Liker, András; Székely, Tamás (5 October 2022). "The evolution of parental care in salamanders - Nature". Scientific Reports. 12 (1): 16655. doi:10.1038/s41598-022-20903-3. PMC 9535019. PMID 36198742.
  74. ^ Reproductive Biology and Phylogeny of Urodela
  75. ^ a b Stebbins & Cohen (1995) pp. 175–179
  76. ^ "Plethodontidae". AmphibiaWeb. Archived from the original on 2015-06-09. Retrieved 2014-01-09.
  77. ^ a b Kiyonaga, Robin R. "Metamorphosis vs. neoteny (paedomorphosis) in salamanders (Caudata)". Archived from the original on 2008-12-01. Retrieved 2008-05-04.
  78. ^ a b Sandoval-Comte, Adriana; Pineda, Eduardo; Aguilar-López, José L. (2012). "In search of critically endangered species: the current situation of two tiny salamander species in the neotropical mountains of Mexico". PLOS ONE. 7 (4): e34023. Bibcode:2012PLoSO...734023S. doi:10.1371/journal.pone.0034023. PMC 3317776. PMID 22485155.
  79. ^ a b Tapley, Benjamin; Bradfield, Kay S.; Michaels, Christopher; Bungard, Mike (2015-07-24). "Amphibians and conservation breeding programmes: do all threatened amphibians belong on the ark?". Biodiversity and Conservation. 24 (11): 2625–2646. Bibcode:2015BiCon..24.2625T. doi:10.1007/s10531-015-0966-9. ISSN 0960-3115. S2CID 11824410.
  80. ^ Fountain, Henry (2009-02-16). "Another Amphibian at Risk: Salamanders". The New York Times. Archived from the original on 2013-11-26. Retrieved 2013-06-28.
  81. ^ "Chinese Giant Salamander". ZSL Conservation. Zoological Society of London. Archived from the original on 2013-06-28. Retrieved 2013-07-21.
  82. ^ Wheeler, Benjamin A.; Prosen, Ethan; Mathis, Alicia; Wilkinson, Robert F. (2003). "Population declines of a long-lived salamander: a 20+-year study of hellbenders, Cryptobranchus alleganiensis". Biological Conservation. 109 (1): 151–156. Bibcode:2003BCons.109..151W. doi:10.1016/s0006-3207(02)00136-2.
  83. ^ Wheeler, Benjamin A.; McCallum, Malcolm L.; Trauth, Stanley E. (2002). "Abnormalities in the Ozark hellbender (Ctyptobranchm alleganiensis bishopi) in Arkansas: a comparison between two rivers with a historical perspective". Journal of the Arkansas Academy of Science. 58: 250–252.
  84. ^ "World's first captive breeding of Ozark hellbenders". Science Daily. 2011-12-01. Archived from the original on 2013-05-11. Retrieved 2013-07-21.
  85. ^ "Lungless salamanders of Mexico". EDGE: Evolutionary distinct and globally endangered. The Zoological Society of London. Archived from the original on 2013-05-29. Retrieved 2013-07-21.
  86. ^ "EDGE of Existence". EDGE of Existence. Archived from the original on 2015-11-17. Retrieved 2015-10-29.
  87. ^ a b Contreras, Victoria; Martínez-Meyer, Enrique; Valiente, Elsa; Zambrano, Luis (2009-12-01). "Recent decline and potential distribution in the last remnant area of the microendemic Mexican axolotl (Ambystoma mexicanum)". Biological Conservation. 142 (12): 2881–2885. Bibcode:2009BCons.142.2881C. doi:10.1016/j.biocon.2009.07.008.
  88. ^ Parra-Olea, G.; Zamudio, K. R.; Recuero, E.; Aguilar-Miguel, X.; Huacuz, D.; Zambrano, L. (2012-02-01). "Conservation genetics of threatened Mexican axolotls (Ambystoma)". Animal Conservation. 15 (1): 61–72. Bibcode:2012AnCon..15...61P. doi:10.1111/j.1469-1795.2011.00488.x. ISSN 1469-1795. S2CID 46992721.
  89. ^ Alcaraz, Guillermina; López-Portela, Xarini; Robles-Mendoza, Cecilia (2015-02-01). "Response of a native endangered axolotl, Ambystoma mexicanum (Amphibia), to exotic fish predator". Hydrobiologia. 753 (1): 73–80. doi:10.1007/s10750-015-2194-4. ISSN 0018-8158. S2CID 17468971.
  90. ^ Figiel, Chester (2013). "Cryopreservation of Sperm from the Axolotl AmbystomA MexicAnum: ImpliCations for Conservation" (PDF). Herpetological Conservation and Biology. Archived (PDF) from the original on 22 March 2016. Retrieved 26 October 2015.
  91. ^ Marcec, Ruth; Bement, Hannah. "Salamander Conservation". Amphibian Conservation. Memphis Zoo. Archived from the original on 2013-07-31. Retrieved 2013-07-21.
  92. ^ Rice, Edward Loranus (1935). An Introduction to Biology. Boston, Massachusetts, USA: Ginn and Company. p. 253.
  93. ^ a b Larson, A.; Dimmick, W. (1993). "Phylogenetic relationships of the salamander families: an analysis of the congruence among morphological and molecular characters". Herpetological Monographs. 7 (7): 77–93. doi:10.2307/1466953. JSTOR 1466953.
  94. ^ Blackburn, David C.; Wake, David B. (23 December 2011). "Class Amphibia Gray, 1825. In: Zhang, Z.-Q. (Ed.) Animal biodiversity: An outline of higher-level classification and survey of taxonomic richness". Zootaxa. 3148 (1). doi:10.11646/zootaxa.3148.1.8.
  95. ^ San Mauro, Diego; Vences, Miguel; Alcobendas, Marina; Zardoya, Rafael; Meyer, Axel (2005). "Initial diversification of living amphibians predated the breakup of Pangaea" (PDF). The American Naturalist. 165 (5): 590–599. doi:10.1086/429523. PMID 15795855. S2CID 17021360.
  96. ^ San Mauro, D. (2010). "A multilocus timescale for the origin of extant amphibians". Molecular Phylogenetics and Evolution. 56 (3): 554–561. doi:10.1016/j.ympev.2010.04.019. PMID 20399871.
  97. ^ Marjanović D, Laurin M (2007). "Fossils, molecules, divergence times, and the origin of lissamphibians". Systematic Biology. 56 (3): 369–388. doi:10.1080/10635150701397635. PMID 17520502.
  98. ^ Schoch, Rainer R.; Werneburg, Ralf; Voigt, Sebastian (2020-05-26). "A Triassic stem-salamander from Kyrgyzstan and the origin of salamanders". Proceedings of the National Academy of Sciences. 117 (21): 11584–11588. Bibcode:2020PNAS..11711584S. doi:10.1073/pnas.2001424117. ISSN 0027-8424. PMC 7261083. PMID 32393623.
  99. ^ de Buffrénil V, Canoville A, Evans SE, Laurin M (2014). "Histological study of karaurids, the oldest known (stem) urodeles". Historical Biology. 27 (1): 109–114. doi:10.1080/08912963.2013.869800. S2CID 83557507.
  100. ^ Marjanovic D, Laurin M (2014). "An updated paleontological timetree of lissamphibians, with comments on the anatomy of Jurassic crown-group salamanders (Urodela)". Historical Biology. 26 (4): 535–550. Bibcode:2014HBio...26..535M. doi:10.1080/08912963.2013.797972. S2CID 84581331.
  101. ^ R. Alexander Pyron; John J. Wiens (2011). "A large-scale phylogeny of Amphibia including over 2800 species, and a revised classification of extant frogs, salamanders, and caecilians". Molecular Phylogenetics and Evolution. 61 (2): 543–583. doi:10.1016/j.ympev.2011.06.012. PMID 21723399.
  102. ^ Sun, Cheng; Shepard, Donald B.; Chong, Rebecca A.; López Arriaza, José; Hall, Kathryn; Castoe, Todd A.; Feschotte, Cédric; Pollock, David D.; Mueller, Rachel Lockridge (2012-01-01). "LTR Retrotransposons Contribute to Genomic Gigantism in Plethodontid Salamanders". Genome Biology and Evolution. 4 (2): 168–183. doi:10.1093/gbe/evr139. PMC 3318908. PMID 22200636.
  103. ^ Elewa, Ahmed; Wang, Heng; Talavera-López, Carlos; Joven, Alberto; Brito, Gonçalo; Kumar, Anoop; Hameed, L. Shahul; Penrad-Mobayed, May; Yao, Zeyu (2017-12-22). "Reading and editing the Pleurodeles waltl genome reveals novel features of tetrapod regeneration". Nature Communications. 8 (1): 2286. Bibcode:2017NatCo...8.2286E. doi:10.1038/s41467-017-01964-9. ISSN 2041-1723. PMC 5741667. PMID 29273779.
  104. ^ Nowoshilow, Sergej; Schloissnig, Siegfried; Fei, Ji-Feng; Dahl, Andreas; Pang, Andy W. C.; Pippel, Martin; Winkler, Sylke; Hastie, Alex R.; Young, George; Roscito, Juliana G.; Falcon, Francisco; Knapp, Dunja; Powell, Sean; Cruz, Alfredo; Cao, Han; Habermann, Bianca; Hiller, Michael; Tanaka, Elly M.; Myers, Eugene W. (2018). "The axolotl genome and the evolution of key tissue formation regulators". Nature. 554 (7690): 50–55. Bibcode:2018Natur.554...50N. doi:10.1038/nature25458. hdl:21.11116/0000-0003-F659-4. PMID 29364872.
  105. ^ Sun, C.; Mueller, R. L. (17 July 2014). "Hellbender Genome Sequences Shed Light on Genomic Expansion at the Base of Crown Salamanders". Genome Biology and Evolution. 6 (7): 1818–1829. doi:10.1093/gbe/evu143. PMC 4122941. PMID 25115007.
  106. ^ Sessions, Stanley K.; Wake, David B. (June 2021). "Forever young: Linking regeneration and genome size in salamanders". Developmental Dynamics. 250 (6): 768–778. doi:10.1002/dvdy.279. PMID 33320991.
  107. ^ Fox, Douglas (February 2022). "Junk DNA Deforms Salamander Bodies". Scientific American. 326 (2): 40.
  108. ^ Fox, Douglas (29 September 2022). "Living mysteries: This critter has 38 times more DNA than you do". Science News Explores.
  109. ^ Benefits of “Zombie” Cells: Senescent Cells Aid Regeneration in Salamanders
  110. ^ Ashcroft, Frances (2002). Life at the Extremes: The Science of Survival. University of California Press. p. 112. ISBN 978-0-520-22234-2.
  111. ^ Pliny the Elder (c. 100). Natural History. pp. Book 10, 86. Archived from the original on 2008-10-18. Retrieved 2014-01-08.
  112. ^ Saint Augustine (c. 500). City of God. pp. Book 21, 4.
  113. ^ Isidore of Seville (c. 700). Etymologies. pp. Book 12, 4:36. Archived from the original on 2008-10-18. Retrieved 2014-01-08.
  114. ^ Browne, Clare (2003). "Salamander's Wool: The Historical Evidence for Textiles Woven with Asbestos Fibre". Textile History. 34: 64–73. doi:10.1179/004049603235001454. S2CID 191599472.
  115. ^ a b White, T. H. (1992) [1954]. The Book of Beasts: Being a Translation From a Latin Bestiary of the Twelfth Century. Alan Sutton. pp. 183–184. ISBN 978-0-7509-0206-9.
  116. ^ Cellini, Benvenuto (1998). The Autobiography of Benvenuto Cellini. England: Penguin Books. p. 34. ISBN 0140447180.
  117. ^ Director: Duncan Chard (2012-02-14). "River Monsters". Programme 6, Series 3. ITV. ITV1.
  118. ^ Holland, Nicholas (2021), "Vicenzo Colucci's 1886 memoir, Intorno alla rigenerazione degli arti e della coda nei tritoni, annotated and translated into English as: Concerning regeneration of the limbs and tail in salamanders", The European Zoological Journal, 88: 837–890, doi:10.1080/24750263.2021.1943549
  119. ^ Keim, Brandon (2009-07-01). "Salamander discovery could lead to human limb regeneration". Wired. Retrieved 2010-05-07.
  120. ^ "Do salamanders' immune systems hold the key to regeneration?". ScienceDaily. Archived from the original on 2013-12-06. Retrieved 2013-05-21.
  121. ^ Symbiotic salamander/algae relationship may inspire new drugs
  122. ^ Goldsmith, Richard (2010-06-11). "Mind-Bending Hallucinogenic Drinks". Fox News. Archived from the original on 2014-12-05. Retrieved 2014-01-02.
  123. ^ Kozorog, Miha (2003). "Salamander Brandy: 'A Psychedelic Drink' Between Media Myth and Practice of Home Alcohol Distillation in Slovenia". Anthropology of East Europe Review. 21 (1): 63–71. Archived from the original on 2014-03-31. Retrieved 2014-03-22.

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