Sanseverino may refer to:

• House of Sanseverino, Neapolitan noble family
• Antonio Sanseverino, (ca. 1477–1543), Neapolitan cardinal
• Ferdinando Sanseverino (1507–1572), prince of Salerno and Italian condottiero
• Aurora Sanseverino (1669–1726), Italian noblewoman and salonniere
• Gaetano Sanseverino (1811–1865), Italian theologian
• Stéphane Sanseverino (born 1961), contemporary French singer, best known as Sanseverino
• Robyn Sanseverino, an FBI agent with a recurring role on HBO's popular crime-drama series, The Sopranos