Shouzhou or Shou Prefecture (壽州) was a zhou (prefecture) in imperial China centering on modern Shou County, Anhui, China. It existed (intermittently) from 589 to 1912.
The administrative region of Shouzhou in the Tang dynasty falls within the administration of modern Lu'an, Anhui. It probably includes parts of modern:
In 956, the Later Zhou state moved the headquarter from modern Shou County further north to modern Fengtai County (now under the administration of Huainan, Anhui).