Sir William Parker Strait is a waterway in the Qikiqtaaluk Region of Nunavut, Canada. It separates Helena Island (to the north-west) from Bathurst Island (to the south-east).

Coordinates: 76°36′34″N 100°39′15″W / 76.60944°N 100.65417°W / 76.60944; -100.65417 (Sir William Parker Strait)