Skye may refer to:

Surname

• Alexis Skye, (born 1974), an American model
• Azura Skye, Azura Dawn Storozynski (born 1981), American actress
• Ione Skye, Ione Skye Lee (born 1970), British-American actress
• Justine Skye (born 1995), an American singer
• Obert Skye, American children's writer

Given name

• Skye Celine Baker (born 1997), Guamanian beauty pageant titleholder
• Skye Blakely (born 2005), American gymnast
• Skye Blue (born 1999), American professional wrestler
• Skye Bolt (born 1994), American baseball player
• Skye Borgman, American film director and cinematographer
• Skye Chan (born 1983), Hong Kong actress
• Skye Dawson (born 1990), former American football player
• Skye Lucia Degruttola (born 2005), British actress
• Skye Drynan, American businesswoman and fashion designer
• Skye Edwards (born 1974), often known as Skye, English singer
• Skye Gyngell (born 1963), Australian chef
• Skye-Jilly Edwards (born 1970), Australian fashion model
• Skye Kakoschke-Moore (born 1985), Australian politician
• Skye Lourie (born 1990), New Zealand-British actress
• Skye McCole Bartusiak (1992–2014), American actress and model
• Skye McNiel (born 1978), American politician
• Skye Nicolson (born 1995), Australian boxer
• Skye Patrick, African-American librarian
• Skye Sweetnam (born 1988), Canadian singer
• Skye Townsend (born 1993), African-American actress and singer
• Skye Wallace, Canadian singer-songwriter

Fictional characters

• Skye, a character in PAW Patrol
• Skye, a fictional eagle in Grandia II
• Skye, an alias of Daisy Johnson, a character from Agents of S.H.I.E.L.D.
• Skye, a character from the video game Darkened Skye
• Skye Chandler Quartermaine, is a fictional character from ABC soap operas
• Skye Miller, a character in the novel and Netflix series 13 Reasons Why
• Skye Nakaiye, a character from The Puzzle Place
• Skye Alexandria Tate, a character in Terra Nova
• Ema and Lana Skye, Ace Attorney characters
• Deirdre Skye, faction leader in Sid Meier's Alpha Centauri
• Skye, a champion in Paladins
• Skye, a character in the battle royale game Fortnite, introduced in Chapter 2 Season 2.
• Skye Masterson, a character from the musical Guys and Dolls