Spatial Cultural-Historical Units of Great Importance (Serbian: Просторне културно-историjске целине од великог значаја/Prostorne kulturno-istorijske celine od velikog značaja) are the monuments in Serbia that have the second level of the State protection.

Those are part of the Cultural Property of Great Importance protection list.

Picture	Name	Municipality/City	Place, Address	Year of inclusion	Info
	Petrovaradin Fortress	Novi Sad	Petrovaradin	1991
	Subotica City Center	Subotica	Subotica	1991
	Cemeteries Out of Use	Novi Sad	Novi Sad	1991
	Greek Lane	Kruševac	Kruševac	1979
	Karačoni Castle	Novi Bečej	Novo Miloševo Maršala Tita No.84	1991
	Ethno Park in Kupinovo	Pećinci	Kupinovo	1991
	Barley Market, Sremska Mitrovica	Sremska Mitrovica	Sremska Mitrovica	1979
	The Historic Core of Sombor - "Venac"	Sombor	Sombor	1991
	Lodine Spa	Novi Sad	Novi Sad	1979
	Godovik Complex	Požega	Godovik	1983
	Kosančićev Venac	Beograd	Stari Grad	1979
	Lukarevina Field	Aleksandrovac	Drenča	1983
	Rural Area with Watermills on Bistrica and Valjavica on the Bistrica river spring.	Petrovac	Bistrica No.	1979
	Novi Sad Synagogue	Novi Sad	Stari Grad Jevrejska ulica	1991
	Memorial Graveyard	Novi Sad	Novi Sad	1991
	Old Town	Belgrade	Grocka	1979
	Old Town	Ivanjica	Ivanjica	1987
	Old City Core	Belgrade	Zemun	1979
	Old City Core	Kragujevac	Kragujevac	1979
	Old City Core	Negotin	Negotin	1983
	Old City Core	Pančevo	Pančevo	1991
	Old Town Core	Pančevo	Banatsko Novo Selo	1991
	Old Town Core	Bečej	Bečej	1991
	Old Town Core	Zrenjanin	Zrenjanin	1991
	Old Town Core	Irig	Irig	1991
	National Heroes Square	Sremska Mitrovica	Sremska Mitrovica	1991
	Čajkino Hill	Vrnjačka Banja	Vrnjačka Banja	1987