Saint Margaret and the Dragon is the title shared by two paintings of Saint Margaret by the Renaissance painter Raphael, both executed in about 1518. One is held in the Kunsthistorisches Museum in Vienna, the other in the Louvre in Paris.
The painting shows the saint at the moment before she is swallowed alive by the dragon. She is shown unafraid, holding the crucifix that will save her once she is swallowed.
This painting was documented in David Teniers the Younger's catalog Theatrum Pictorium of the art collection of Archduke Leopold Wilhelm in 1659 and again in 1673, but the portrait had already enjoyed notoriety in Teniers' portrayals of the Archduke's art collection.
Another version showing the central figure holding a palm branch is in the collection of the Louvre.