TAOK2
Identifiers
Aliases	TAOK2, MAP3K17, PSK, PSK1, PSK1-BETA, TAO1, TAO2, TAO kinase 2, Tao2beta
External IDs	OMIM: 613199 MGI: 1915919 HomoloGene: 74531 GeneCards: TAOK2
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p11.2 Start 29,973,868 bp[1] End 29,992,261 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F3 Start 126,464,850 bp[2] End 126,483,875 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lung anterior pituitary upper lobe of left lung right lobe of thyroid gland cingulate gyrus spleen left lobe of thyroid gland right uterine tube canal of the cervix tibial nerve Top expressed in superior frontal gyrus lip esophagus yolk sac spermatocyte thymus cerebellar cortex neural tube hand islet of Langerhans More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity nucleotide binding protein kinase activity kinase activity protein serine/threonine kinase activity mitogen-activated protein kinase kinase binding ATP binding MAP kinase kinase kinase activity neuropilin binding tau protein binding tau-protein kinase activity Cellular component integral component of membrane cell projection membrane receptor complex dendrite nucleolus cytoskeleton cytoplasmic vesicle membrane nucleus cytoplasm cytosol cytoplasmic vesicle actin cytoskeleton axon neuron projection dendritic growth cone axonal growth cone Biological process phosphorylation protein targeting to membrane response to stress positive regulation of JNK cascade cellular response to DNA damage stimulus protein phosphorylation focal adhesion assembly stress-activated MAPK cascade regulation of cell growth regulation of cell shape cell migration actin cytoskeleton organization positive regulation of stress-activated MAPK cascade apoptotic process regulation of mitotic cell cycle nervous system development regulation of apoptotic process mitotic G2 DNA damage checkpoint signaling axonogenesis signal transduction stress-activated protein kinase signaling cascade positive regulation of protein autophosphorylation activation of protein kinase activity regulation of actin cytoskeleton organization protein autophosphorylation basal dendrite morphogenesis basal dendrite arborization Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9344 381921 Ensembl ENSG00000149930 ENSMUSG00000059981 UniProt Q9UL54 Q6ZQ29 RefSeq (mRNA) NM_001252043 NM_004783 NM_016151 NM_001163774 NM_001163775 RefSeq (protein) NP_001238972 NP_004774 NP_057235 NP_001157246 NP_001157247 Location (UCSC) Chr 16: 29.97 – 29.99 Mb Chr 7: 126.46 – 126.48 Mb PubMed search [3] [4]
Wikidata
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Serine/threonine-protein kinase TAO2 is an enzyme that in humans is encoded by the TAOK2 gene.^[5][6][7]

Interactions

TAOK2 has been shown to interact with MAP2K6^[8] and MAP2K3.^[8]