Protein-coding gene in the species Homo sapiens
Testis expressed 11 is a protein that in humans is encoded by the TEX11 gene .
[5]
Function
This gene is X-linked and is expressed in only male germ cells. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Wang PJ, McCarrey JR, Yang F, Page DC (April 2001). "An abundance of X-linked genes expressed in spermatogonia". Nat. Genet . 27 (4): 422–6. doi :10.1038/86927 . PMID 11279525 . S2CID 14200121 . Aston KI, Krausz C, Laface I, Ruiz-Castané E, Carrell DT (June 2010). "Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent" (PDF) . Hum. Reprod . 25 (6): 1383–97. doi :10.1093/humrep/deq081 PMID 20378615 . Yatsenko AN, Georgiadis AP, Röpke A, Berman AJ, Jaffe T, Olszewska M, Westernströer B, Sanfilippo J, Kurpisz M, Rajkovic A, Yatsenko SA, Kliesch S, Schlatt S, Tüttelmann F (May 2015). "X-linked TEX11 mutations, meiotic arrest, and azoospermia in infertile men" . N. Engl. J. Med . 372 (22): 2097–107. doi :10.1056/NEJMoa1406192 . PMC 4470617 PMID 25970010 . Yang F, Silber S, Leu NA, Oates RD, Marszalek JD, Skaletsky H, Brown LG, Rozen S, Page DC, Wang PJ (September 2015). "TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse" . EMBO Mol Med . 7 (9): 1198–210. doi :10.15252/emmm.201404967 . PMC 4568952 PMID 26136358 . Yang F, Silber S, Leu NA, Oates RD, Marszalek JD, Skaletsky H, Brown LG, Rozen S, Page DC, Wang PJ (September 2015). "TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse" . EMBO Mol Med . 7 (9): 1198–210. doi :10.15252/emmm.201404967 . PMC 4568952 PMID 26136358 . This article incorporates text from the United States National Library of Medicine , which is in the public domain .
