TL-599
Names
Preferred IUPAC name
4-[(Dimethylcarbamoyl)oxy]-N,N,N-trimethyl-2-(propan-2-yl)anilinium iodide
Other names
SB-8
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C15H25N2O2.HI/c1-11(2)13-10-12(19-15(18)16(3)4)8-9-14(13)17(5,6)7;/h8-11H,1-7H3;1H/q+1;/p-1
    Key: DBMNNBLVHXQGOH-UHFFFAOYSA-M
  • CC(C)c1cc(ccc1[N+](C)(C)C)OC(=O)N(C)C.[I-]
Properties
C15H25IN2O2
Molar mass 392.281 g·mol−1
Hazards
Lethal dose or concentration (LD, LC):
75 μg/kg (subcutaneous, mice)[1]
168 μg/kg (intraperitoneal, mice)[1]
75 μg/kg (mice, subcutaneous)[2]
100 μg/kg (guinea pigs, subcutaneous)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

TL-599, also known as SB-8, is an extremely potent carbamate acetylcholinesterase inhibitor.[1][2]

See also

References

  1. ^ a b c d Chemical Warfare Agents, and Related Chemical Problems. Parts I-II.
  2. ^ a b Stevens, Joseph R.; Beutel, Ralph H. (January 1941). "Physostigmine Substitutes". Journal of the American Chemical Society. 63 (1): 308–311. doi:10.1021/ja01846a078.
Categories