TRAP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4Z1F, 4Z1G, 4Z1H, 4Z1I, 5F3K, 5F5R
Identifiers
Aliases	TRAP1, HSP 75, HSP75, HSP90L, TRAP-1, TNF receptor associated protein 1
External IDs	OMIM: 606219 MGI: 1915265 HomoloGene: 9457 GeneCards: TRAP1
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p13.3 Start 3,651,639 bp[1] End 3,717,553 bp[1]
Gene location (Mouse) Chr. Chromosome 16 (mouse)[2] Band 16 A1|16 2.38 cM Start 3,857,835 bp[2] End 3,895,691 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube gastrocnemius muscle triceps brachii muscle right lobe of liver body of pancreas skin of abdomen islet of Langerhans gastric mucosa left ventricle vastus lateralis muscle Top expressed in Paneth cell masseter muscle proximal tubule skeletal muscle tissue brown adipose tissue kidney sternocleidomastoid muscle tibialis anterior muscle yolk sac temporal muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding unfolded protein binding protein binding tumor necrosis factor receptor binding ATP binding protein kinase binding RNA binding Cellular component membrane mitochondrial intermembrane space lipid droplet nucleoplasm mitochondrial matrix mitochondrion mitochondrial inner membrane extracellular exosome Biological process response to stress negative regulation of cellular respiration protein folding negative regulation of reactive oxygen species biosynthetic process translational attenuation chaperone-mediated protein folding negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10131 68015 Ensembl ENSG00000126602 ENSMUSG00000005981 UniProt Q12931 Q9CQN1 RefSeq (mRNA) NM_001272049 NM_016292 NM_026508 RefSeq (protein) NP_001258978 NP_057376 NP_080784 Location (UCSC) Chr 16: 3.65 – 3.72 Mb Chr 16: 3.86 – 3.9 Mb PubMed search [3] [4]
Wikidata
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Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene.^[5][6][7]

Interactions

TRAP1 has been shown to interact with EXT2,^[8] EXT1^[8] and Retinoblastoma protein.^[9]