Takatsukasa Masahiro (鷹司 政煕, May 14, 1761 – March 29, 1841) was a Japanese court noble of the Edo period. He held the regent position of kampaku from 1795-1814.
Masahiro was born the son of regent Takatsukasa Sukehira.
He served as kampaku from 1795-1814.
He had a son, Masamichi, with the daughter of the 11th head of Tokushima Domain, Hachisuka Shigeyoshi.