| Rank | Name | Autonomous community | Pop. | Rank | Name | Autonomous community | Pop. | ||
|---|---|---|---|---|---|---|---|---|---|
 Madrid  Barcelona |
1 | Madrid | Community of Madrid | 3,266,126 | 11 | Alicante | Valencian Community | 334,887 |  Valencia  Seville |
| 2 | Barcelona | Catalonia | 1,608,746 | 12 | Córdoba | Andalusia | 325,701 | ||
| 3 | Valencia | Valencian Community | 794,288 | 13 | Valladolid | Castile and León | 298,412 | ||
| 4 | Seville | Andalusia | 688,592 | 14 | Vigo | Galicia | 295,364 | ||
| 5 | Zaragoza | Aragon | 674,997 | 15 | Gijón | Principality of Asturias | 271,780 | ||
| 6 | Málaga | Andalusia | 574,654 | 16 | L'Hospitalet | Catalonia | 254,804 | ||
| 7 | Murcia | Region of Murcia | 453,258 | 17 | Vitoria-Gasteiz | Basque Country | 251,774 | ||
| 8 | Palma | Balearic Islands | 416,065 | 18 | A Coruña | Galicia | 245,711 | ||
| 9 | Las Palmas | Canary Islands | 379,925 | 19 | Elche | Valencian Community | 232,517 | ||
| 10 | Bilbao | Basque Country | 346,843 | 20 | Granada | Andalusia | 232,462 | ||