Thomas or Tom(my) Dean or Deen may refer to:

• Thomas Dean (cricketer, born 1920) (1920–2004), English cricketer
• Tom Dean (Gloucestershire cricketer) (1881–1964), cricketer who played once for Gloucestershire in 1908
• Tom Dean (artist), Canadian conceptual artist
• Tommy Dean (born 1945), shortstop in Major League Baseball
• Thomas Dean (computer scientist), professor at Brown University and researcher at Google
• Tom Dean (swimmer) (born 2000), British swimmer
• Tom Dean (basketball), see Morgan State Bears men's basketball
• Tommy Dean (comedian), American-Australian comedian who appeared on Stand Up Australia
• Thomas Dean (mechanic), see Henkes Islands
• Thomas B. Deen, see List of members of the National Academy of Engineering