Thyroglobulin type-1 repeat

Thyroglobulin type-1 domain

Identifiers

Symbol

Thyroglobulin_1

1icf / SCOPe / SUPFAM

CDD

cd00191

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary
PDB	1icfI:213-271 1l3hA:213-271 1rmjA:163-234 1zt3A:176-251 1zt5A:176-251

Thyroglobulin type-1 repeat is an evolutionary conserved protein domain. Thyroglobulin type 1 repeats are thought to be involved in the control of proteolytic degradation. The domain usually contains six conserved cysteines. These form three disulphide bridges. Cysteines 1 pairs with 2, 3 with 4 and 5 with 6.

Human proteins containing this domain

CD74; IGFBP-4; IGFBP1; IGFBP2; IGFBP3; IGFBP4; IGFBP5; IGFBP6; NID1; NID2; SMOC1; SMOC2; SPOCK1; SPOCK2; SPOCK3; TACSTD1; TACSTD2; TG;

Human proteins containing this domain

References