Tienoxolol
Names
IUPAC name
Ethyl 2-[3-(tert-butylamino)-2-hydroxypropoxy]-5-(thiophene-2-carbonylamino)benzoate
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C21H28N2O5S/c1-5-27-20(26)16-11-14(23-19(25)18-7-6-10-29-18)8-9-17(16)28-13-15(24)12-22-21(2,3)4/h6-11,15,22,24H,5,12-13H2,1-4H3,(H,23,25)
    Key: PHMRLCQEIQGCHH-UHFFFAOYSA-N
  • InChI=1/C21H28N2O5S/c1-5-27-20(26)16-11-14(23-19(25)18-7-6-10-29-18)8-9-17(16)28-13-15(24)12-22-21(2,3)4/h6-11,15,22,24H,5,12-13H2,1-4H3,(H,23,25)
    Key: PHMRLCQEIQGCHH-UHFFFAOYAL
  • CCOC(=O)C1=C(C=CC(=C1)NC(=O)C2=CC=CS2)OCC(CNC(C)(C)C)O
Properties
C21H28N2O5S
Molar mass 420.52 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Tienoxolol is a beta adrenergic receptor antagonist.[1]

References

  1. ^ Mahé, N; Do, B; Nicolaï, B; Rietveld, IB; Barrio, M; Tamarit, JL; Céolin, R; Guéchot, C; Teulon, JM (2012). "Crystal structure and solid-state studies of aged samples of tienoxolol, an API designed against hypertension". International Journal of Pharmaceutics. 422 (1–2): 47–51. doi:10.1016/j.ijpharm.2011.10.025. hdl:2117/14578. PMID 22027392.



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