Prior to 18th century
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- 2nd. half of the 4th millennium BCE - The territory of Cagliari is inhabited by people of the so-called neolithic civilization of Ozieri. Some Domus de Janas were dug in Mount Saint Elias
- 2nd. half of the 3rd millennium BCE - The territory of Cagliari is the core of the Chalcolithic civilization of Monte Claro
- 8th C. BCE - Caralis founded by Phoenicians from Tyre, Lebanon.[1]
- 510 BCE - Caralis occupied by the Cartaginians
- 238 BCE - Caralis occupied by the Romans
- Early 1st C. CE - Granting of the title of Municipium
- 2nd C. CE - Roman Amphitheatre of Cagliari built.
- 5th C. CE - Roman Catholic diocese of Cagliari established (approximate date).[2]
- 5th C. CE - Basilica of San Saturnino built.
- 485 - Vandals in power in Sardinia.[3](it)
- 533 - Sardinia taken by forces of Justinian I.[3]
- 10th C. - The title of imperial Protospatharios is granted to the Iudex Sardiniae Turcoturios (Tουρκοτούριος), resident in Caralis, by the Byzantine emperors.
- 1020 - Giudicato of Cagliari established.
- 1297 - Pope Boniface VIII invests the Kings of Aragon with Sardinia.[3]
- 1305 - Torre di San Pancrazio (tower) built.[3]
- 1307 - Torre dell'Elefante (tower) built.[3]
- 1312 - Cagliari Cathedral built.[3]
- 1323 - Siege of Castel di Castro begins during the Aragonese conquest of Sardinia.
- 1325
- December: Battle of the Golfo di Cagliari.
- Shrine of Our Lady of Bonaria construction begins.[1]
- 1326 - Siege of Castel di Castro ends; Aragonese in power.[1]
- 1348 - Black Death plague.[3]
- 1492 - Jews in Sardinia expelled per Alhambra Decree.(it)
- 1606 - University of Cagliari established.[3]
- 1688 - Population: 17,390.(it)
