Below is a timeline of events in Hamilton, Ontario, Canada.
- 1860 – First tap water in the city.
- 1860 – The Crystal Palace opened up at Victoria Park 20 September 1860. It was home to the area's largest fall fair for many years. The local Hamilton Herald newspaper was quoted as saying on 22 September 1890, "The Carnival of Venice, The Paris Exposition or the World's Fair in Chicago will be nowhere tomorrow when the great Central Fair is opened at the Crystal Palace Grounds in this city." The structure was demolished in 1891.
- 1860 – First railway sleeping car built in Hamilton.
- 1862 – The city had invested in the Great Western Railway (Ontario) but the government of Canada favoured the rival Grand Trunk Railway. Also the end of the Depression (1857–1862) and population dips downwards in Hamilton and the city could not meet the interest on its bonds, many of which were held by British investors. To save the city from its creditors temporarily, Thomas Beasley removes the assessment rolls, thus preventing a levy of special tax. Foundries and machine shops associated with the Great Western Railway failed and several established wholesalers closed their accounts. Daniel C. Gunn's locomotive works went bankrupt, but the manufacturers of farm implements and stoves-the mainstays of iron foundries – were able to weather the crisis. Those owned by Dennis Moore and the Copp brothers endured, but their employees suffered wage cuts and layoffs. Canadian patent laws and the underemployed workers skilled in machinist trades lured an important new industrial enterprise from the U.S.A. – the manufacture of sewing machines by Richard Wanzer. From this development there evolved the ready-made clothing industry, which William Eli Sanford introduced locally. From judicial village to commercial town to railway centre, Hamilton moves to an ever-stronger dependency on industry.
- 1862 – Isaac Buchanan who was the 1st Commanding Officer of that Regiment.
LCol The Hon. Isaac Buchanan commanded the 13th from 28 Nov 1862 until 30 Dec 1864. The XIIIth Battalion is known today as The Royal Hamilton Light Infantry (Wentworth Regiment).
- 1864 – First Board of Trade – Hon. Isaac Buchanan, President. 27 churches and 77 taverns in the city.
- 1867 – Confederation of Canada.
- 1868 – Hottest day ever recorded in Hamilton as the thermometer hits 41.4 °C 
- 1869 – On Wednesday, November 3, 1869, in a room above George Lee's Fruit Store, the Hamilton Football Club was formed. Hamilton Football Clubs have captured the Grey Cup in every decade of the 20th century, a feat matched in pro sport by only one other franchise, the Montreal Canadiens.
TH&B locomotive No. 22 with crew, circa 1900–1910
- 1890 – First organized hockey game held in Hamilton; Bank of Hamilton vs. Knox, Morgan. (this is the earliest reference to an organized hockey game being played in Hamilton.)
- 1890 – Hamilton's first public library opens up on Main Street West. Officially opened up by Lord and Lady Aberdeen on September 16, 1890.
- 1890 – First bowling alley in the city opens at back of the J.W. MacDonald Tobacco shop, (66 James Street North).
- 1892 – June 29, 1892, is the date the first electric streetcar was operated in Hamilton. The first two electric routes were King Street East and James Street North. Street cars continued running on Hamilton streets until 6 April 1951.
- 1892 – The Toronto, Hamilton and Buffalo Railway began operations.
- 1892 – The Hamilton Street Railway (HSR) converted to electrically powered vehicles in 1892.
- 1892 – James Street incline railway opens up June 11 (1892–1932).
- 1893 – Hamilton's first large department store opens: the Right House (King Street).
- 1893 – The Sir John A. Macdonald statue arrives in Hamilton from London, England on 30 October 1893. Official dedication of the statue took place 1 November 1893. Located at the intersection of King and Hughson Streets. Prime Minister Sir John Thompson in attendance.
- 1893 – Hamilton Electric Light Co. electrify the street railway.
- 1894 – Harvey Park was named after Colonel John Harvey, a British officer during the War of 1812. The name was accepted by Hamilton City Council 11 June 1894. (situated just west of Dundurn Park).
- 1894 – Hamilton Herald newspaper and cigar store owner Billy Carroll established the Around the Bay Road Race. Although it is not a proper marathon, it is the longest continuously held long-distance foot race in North America.
- 1895 – Wentworth incline railway begins operation in August 1895. (1895–1936)
- 1895 – The TH&B Railway came into Hamilton in 1895. A railway tunnel was then constructed from Queen to Park Street to cut down on the noise, pollution and disruption for the wealthy families who lived South of Jackson Street in the Durand neighbourhood.
- 1896 – Cataract Power Company of Hamilton was incorporated, later becoming the Dominion Power and Transmission Company acquires water privilege at Decew Falls. Nikola Tesla (the inventor of the AC Polyphase system of generators, transformers and motors) consulted about the plans to built a power generating station in St Catharines at Decew Falls and to send to power to Hamilton. Tesla approved the plans.
- 1896 – Sir John Morison Gibson forms The Dominion Power and Transmission Company, that brought hydroelectric power, for the first time, to Hamilton, from their plant, at DeCrew Falls.
- 1896 – Hamilton Radial Electric Railway extended across Beach Strip. (7 September 1896).
- 1896 – Hamilton firefighters unionized.
- 1897 – John M. Lyle, Hamilton architect in the late 19th century and early 20th century, designs New York Public Library Main Branch in 1897. (Later went on to design the Royal Alexandra Theatre, in Toronto (1907) and Union Station (Toronto) 1914–1921).
- 1897 – Adelaide Hoodless, was a Canadian educational reformer who founded the international women's organization known as the Women's Institutes in 1897.
- 1897 – Westinghouse established in Hamilton. first Westinghouse operation outside of the U.S.
- 1898 – The "Five Johns", (John Patterson, John Dickenson (Canadian politician), John Morison Gibson, John Moodie Sr. and John Sutherland), form The Cataract Power Co. Ltd. introducing electric power to Hamilton in 1898. On August 25, 1898, power was sent twenty seven miles from DeCew Falls, St. Catharines, using water from the old Welland Canal. New industries, such as the forerunners of the Steel Co. of Canada (Stelco) and Canadian Westinghouse, were attracted here by the cheaper, more efficient power. One time this Company controlled hydro power from Brantford to St. Catharines, including the Hamilton Street Railway and the area's radial lines. Back then the city's nickname was "The Electric City."
- 1898 – The first automobile driven in Canada was by textile manufacturer John Moodie in 1898; A one-cylinder Winton he imported from Cleveland. John Moodie was also one of the founders of Canada's automobile club, the Hamilton Automobile Club (now CAA South Central Ontario), which was founded in 1903 when there were 18 cars in town. By 1920, there were 6,000 and Hamilton's ratio of one car for every 15 people was higher than that of New York, Chicago, Boston or Toronto.
- 1899 – Thomas Bain in 1899 becomes the Speaker of the House of Commons of Canada in Ottawa.
- 1899 – Dundurn becomes a city park and the Victorian Order of Nurses begin work in Hamilton.
Copps Coliseum, at York Boulevard, looking East
Sam Lawrence Park, Concession Street landmark
- 1980 – The Hamilton Central Library and Farmers Market opened.
- 1981 – The Hamilton Convention Centre and the government office tower above it opened. The tower was named the Ellen Fairclough Building in 1982.
- 1982 – Bob Morrow wins the first of six mayoral elections, defeating incumbent John Alexander McDonald. Bob Morrow serves as Mayor of Hamilton from 1983-to-2000 and becomes longest-serving mayor in Hamilton's history.
- 1983 – The Standard Life Centre opened at the west end of Jackson Square.
- 1983 – Renovations began at Gore Park, including cutting down all the mature trees and constructing an amphitheatre. What came to be known as the Gore Park Fiasco was stopped by citizen protests, redesigned and completed in November 1984.
- 1985 – Daniel Lanois, a solo artist in his own right and producer for U2, opens up Grant Avenue Studios in Hamilton, Ontario.
- 1985 – Sheraton Hamilton, connected to Jackson Square, opened, boosting downtown's hotel space.
- 1985 – Copps Coliseum, sports and entertainment arena with a capacity of up to 19,000 (depending on event type and configuration) opens its doors for business. It is named after the former Hamilton mayor, Victor K. Copps.
- 1985, November – Hamilton Street Railway uses first Natural Gas Vehicle (N.G.V.) buses in North America.
- 1986 – World Junior Ice Hockey Championship Games in 1986 at Copps Coliseum which saw the Soviets capture gold against Team Canada with a top scoring line that consisted of Sergei Fedorov, Alexander Mogilny and Pavel Bure.
- 1986 – The popular downtown restaurant The Chicken Roost closed.
- 1987 – #99 Wayne Gretzky and #66 Mario Lemieux combine forces to capture the Canada Cup at Copps Coliseum as Team Canada defeat the Russians. Canada wins series 2 games to one. All three games end in 6-to-5 scores.
- 1987 – The first of two reflective glass buildings of the CIBC tower (Commerce Place I) opened at King and James opposite Gore Park. The other (Commerce Place II) opened in 1990.
- 1989 – The original name of the first bridge was the Burlington Bay Skyway. After it was twinned, the proposed names of "James N. Allan Skyway" (in honour of the Ontario minister who championed the 1958 bridge) and "James N. Allan Burlington Bay Skyway" were rejected. The official name since 1989 has been "Burlington Bay James N. Allan Skyway", while it is referred to by the public simply as the "Skyway Bridge".
- 1989 – The Robinson's store on James South between Main and King closed and was demolished shortly afterward.
- 1989 – The Unified Family Court opened in the old central library on Main Street.
- 1989 – The Tivoli Theatre on James North closed.
- 1989 – The Century Theatre on Mary Street closed.
- 1989 – Fire destroyed two 1840s buildings at the northeast corner of King and John.
2000 – present
Hamilton Tiger-Cats vs. Toronto Argonauts, October 27, 2005, at Rogers Centre
Stinson, 100-storey Connaught Towers presentation, Hamilton Chamber of Commerce, (Monday June 2nd, 2008)
- 2000 – LIUNA reopened the James North CN rail station as a banquet hall.
- 2001 – The new city of Hamilton is formed. The Regional Municipality of Hamilton-Wentworth and its six local municipalities; Ancaster, Dundas, Flamborough, Glanbrook, Hamilton and Stoney Creek amalgamate. (January 1) 
- 2001 – The Juno Awards of 2001 were held in Hamilton, Ontario, hosted by Rick Mercer at Copps Coliseum and broadcast on CBC Television. Performers during the telecast included: Deborah Cox, Nelly Furtado, The Guess Who, Jacksoul, Michie Mee, The Moffatts and Treble Charger.
- 2002 – Pat Quinn, At the 2002 Olympic Winter Games coached Team Canada to their first Olympic gold medal in ice hockey at the Olympic Games since 1952.
- 2003 – Hamilton Bulldogs of the AHL lose in the Calder Cup Finals to the Houston Aeros.
- 2003 – On August 30, 2003, the 60th anniversary of her commissioning into the Royal Canadian Navy, HMCS Haida (G63) (Canada's most famous warship and the last remaining Tribal Class in the world) was moved to the city of Hamilton, Ontario by Parks Canada where she has become a focal point of a revitalized waterfront.
- 2003 – Michael DeGroote, makes a $105 million CAD donation was given to McMaster's medical program. It is the largest single cash gift in Canadian history and will be used to upgrade the current medical school, called the Michael G. DeGroote School of Medicine.
- 2003 – The Hamilton Golf & Country Club hosted the 2003 Canadian Open golf championship in which Bob Tway won.
- 2003 – Hamilton successfully hosted the World Cycling Championships in 2003. It was only the second time the World Cycling Championships was staged outside of Europe, first time ever in Canada. Igor Astarloa of Spain was the winner.
- 2004 – Dave Andreychuk, captains the Tampa Bay Lightning of the NHL to the 2004 Stanley Cup.
- 2006 – Hamilton hosts the Canadian Open Golf Championship again in 2006 Jim Furyk won the title.
- 2006 – As of October 5, 2006, speculation has it that Jim Balsillie of Research In Motion who offered to buy the Pittsburgh Penguins for $175-million would move the team to Hamilton where it would play out of the Copps Coliseum Arena.
- 2006 – On December 15, 2006, Balsillie withdrew his bid to buy the Pittsburgh Penguins. He made the decision after receiving notice from NHL commissioner Gary Bettman that the league would restrict Balsillie's control over the team. The move was geared at preventing Balsillie from moving the team.
- 2006 – The Hamilton Port Authority handles over 12 million tons of cargo and is visited by over 700 vessels each year. This ranks Hamilton as the busiest of all Canadian Great Lakes ports.
- 2007 – Hamilton hosts the 2007 Tim Hortons Brier (March 3–11).
- 2007 – Ronald V. Joyce Stadium at McMaster University opens up. Used for football, soccer and rugby.
- 2007 – David Braley Athletic Centre at McMaster University opens up.
- 2007 – Cayuga International Speedway (now Jukasa Motor Speedway), a 5/8-mile oval auto racing track reopens in 2007 after major renovations.
- 2007 – Henderson General Hospital on Concession Street (April 2007) major renovations and expansion started and once complete the hospital will be renamed the Juravinski Hospital and Cancer Centre, (after Charles Juravinski and his wife Margaret), after they both made a $43-million contribution to health care in Hamilton.
- 2007 – Hamilton Bulldogs win the Calder Cup, defeating the Hershey Bears 2–1 before sellout crowd at Copps Coliseum.
- 2007 – Hamiltonian Brian Melo wins the fifth season of Canadian Idol.
- 2007 – Red Hill Valley Parkway (popularly called the Red Hill Creek Expressway) a municipal expressway running through the city, connecting the Lincoln M. Alexander Parkway to the Queen Elizabeth Way near Hamilton Harbour. A four-lane freeway completed in 2007. The parkway was originally scheduled to be opened to vehicular traffic on November 16 but the date was pushed back a day and officially opened November 17.
- 2007 – Jim Balsillie of Waterloo, Ontario-based Research In Motion, offers to manage and run HECFI, (Hamilton Entertainment and Convention Facilities), which includes Copps Coliseum, Hamilton Place and Convention Centre. Also, offers to upgrade and renovate the Copps Coliseum Arena to make it a 2007 NHL-ready Arena. Price tag for renovations/ upgrades, $100-million (minimum). Name of Jim Balsillie's company that will run and manage all 3-Hamilton landmarks is "Golden Horseshoe Sports & Entertainment."
- 2007 – September 19, CBC organized a meeting in Hamilton at the Convention Centre to discuss the idea of bringing a new radio station to the City citing that 'Hamilton was the largest, and most underrepresented city in the country in terms of media coverage.' 
- 2007 – Centre Mall owners announce plans for a 23-building super centre on the property on Barton Street East. Cost is estimated to be around $100-million and will take up 700,000 square feet (65,000 m2) of retail space. This will end up being the largest redevelopment project in the history of Hamilton's east-end.
- 2007 – It is announced on October 4, that the Mountain Plaza Mall at Fennell Avenue and Upper James Street is to be rebuilt in a $50-million project. Announcement made on October 4 by Flavio Volpe, spokesperson for Smart Centres Ltd., Vaughan-based company that bought the Mall in November 2006.
- 2008 – On Friday, February 29, 2008, Hamilton, Ontario Wikipedia page became the "FEATURED ARTICLE."
- 2008 – May 2, 2008, Hamilton's most powerful voices in business, the arts, government, social services, health and education called for "breathtaking" change and a reinvention of Hamilton's image at the city's first ever economic summit.
- 2008 – June 2, 2008, Real Estate developer Harry Stinson makes a public presentation of his proposed 100-storey Connaught Towers at the Hamilton Chamber of Commerce building. It would have made it the tallest building in Canada. Three months later, on Thursday September 4, Harry Stinson closes up the Connaught Towers sales office in downtown Hamilton and the project is officially cancelled.
- 2008 – Hamilton hosts the Vanier Cup. (Championship trophy of Canadian Interuniversity Sport men's football.)
- 2009 – Prince Charles, Prince of Wales and Camilla, Duchess of Cornwall visit Dundurn Castle and HMCS Haida.
- 2009 – Toronto/ Hamilton wins 2015 Pan American Games bid.
- 2010 – June 23, 2010, A 5.0 magnitude earthquake hit Ontario (including Hamilton)