Timothy Leighton | |
|---|---|
 Timothy Leighton at the Royal Society admissions day in London, July 2014 | |
| Born | Timothy Grant Leighton 16 October 1963[2] Blackburn, Lancashire |
| Education | Heversham Grammar School, Cumbria |
| Alma mater | University of Cambridge (MA, PhD) |
| Known for | The Acoustic Bubble[3][4] |
| Awards |
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| Scientific career | |
| Fields | |
| Institutions | |
| Thesis | Image intensifier studies of sonoluminescence, with application to the safe use of medical ultrasound (1988) |
| Website | southampton |
Timothy Grant Leighton FRS FREng FMedSci[5][6][7][8] (born 16 October 1963)[2][3] is the Professor of Ultrasonics and Underwater Acoustics at the University of Southampton.[9][10][11][12][13][14] He is the inventor-in-chief of Sloan Water Technology Ltd.,[15] a company founded around his inventions. He is an academician of three national academies.[5] Trained in physics and theoretical physics, he works across physical, medical, biological, social and ocean sciences, fluid dynamics and engineering. He joined the Institute of Sound and Vibration Research (ISVR) at the University of Southampton in 1992 as a lecturer in underwater acoustics, and completed the monograph The Acoustic Bubble[3] in the same year. He was awarded a personal chair at the age of 35 and has authored over 400 publications.[10][16][17]
He was educated at Heversham Grammar School, Cumbria and Magdalene College, Cambridge where he took the Natural Sciences Tripos and was awarded a double first class Bachelor of Arts degree with honours in physics and theoretical Physics in 1985, obtaining a PhD in 1988 at the Cavendish Laboratory, University of Cambridge.[2][18][19][20] Following his PhD, he was awarded senior and advanced research fellowships at Magdalene College, Cambridge funded by the Engineering and Physical Sciences Research Council (EPSRC).[21]
He joined the Institute of Sound and Vibration Research (ISVR) at the University of Southampton in 1992 as a lecturer in underwater acoustics, and completed the monograph The Acoustic Bubble[3] in the same year. He was awarded a personal chair at the age of 35.
He founded and leads two research organisations he founded (Global-NAMRIP and HEFUA), is the executive general director and inventor-in-chief of Sloan Water Technology Ltd.,[15] and talks extensively to schoolchildren, the public,[22] and on radio and video.[23]
His research covers medical, humanitarian and environmental sciences, beginning with the fundamental mathematics and ending with engineering applications. His research interests cover acoustical oceanography, antimicrobial resistance,[24][25] biomedical ultrasound,[26] carbon capture and storage,[27][28][29] climate change,[28][30][31][32] decontamination,[33] hospital acquired infections,[34] marine zoology,[35][36] fluid dynamics, ultrasound and underwater acoustics. Working in such fields as cold water cleaning,[34] sound in space,[37][38][39][40] ultrasound in air,[41][42] BiaPSS,[43] TWIPR,[14] and passive acoustic lithortripsy monitoring,[44][45][46][47] he emphasized the need to push pioneering research into game-changing technology,[48][49][50][51][19] as opposed to incremental research that is published but falls short of societal benefit:[52]
...We need to work with rigour, imagination, and wonder, unconstrained by the artificial boundaries set in place by discipline names, or the history of projects in which we have previously worked, or the tendency of sponsors to believe they can pick winners, or above all by the belief that we must jump to solutions when we have not yet perceived the real problem. Then, when we eventually do find a solution, we must have the will to push it through all the way to help others, and not simply publish in the expectation that someone will finish the job for us.[16]
He worked as part of the team investigating whether man-made sounds can adversely affect benthic species (marine life that inhabits the seabed).[53][54] Such species have been overlooked in studies on how man-made sounds affect whales, dolphins and fish: benthic species find it far harder to relocate away from adverse sounds than do these other more mobile species. Furthermore, benthic species play a key role in the health of the marine sediment, turning it over and preventing it stagnating, and are key to the health of coastal marine environments.[35][55]
With other teams he developed methods to assess which fish species are most at-risk from man-made noise in the oceans,[56] and quantified such noise from shipping.[57] Turning the problem on its head, he worked with other teams on how to use sound as 'underwater acoustic scarecrows' to guide fish away from regions of man-made danger. These might occurs, for example, where industry exacts cooling water from rivers used as migration paths of endangered species (the young of European eel are slim enough for the flow to pull them through grills placed over such extraction points).[58][59][60][61][62][63][64][65] (key collaborator: Paul White[66]).
The Global Network for AntiMicrobial Resistance and Infection Prevention (Global-NAMRIP),[24] is a multidisciplinary research team of hundreds researchers and end users, across four continents, including engineers, chemists, microbiologists, environmental scientists, veterinary and human medics, clinicians who contribute to international and national antibiotic guidelines for specified conditions, experts in food, ethics and law, crucially networked with economists, geographers, health scientists and experts from other social science disciplines to provide a truly joined up approach to antimicrobial resistance (AMR) and infection prevention (offsetting the loss of diversity in pharmaceutical industry research teams). As Leighton said at NAMRIP's 2016 conference:
...Unless preventative measures are found (and no-one in the world currently knows what those will be), AMR will (through the colloquial 'rise of superbugs') by 2050 be killing more people than cancer, and cost the world economy more than the current size of the global economy. We will not be able to feed the world unless we wean our food production industry off its dependence on antibiotics; common medical procedures (minor surgery, childbirth) will become significantly more hazardous; and advances in treatments (such as those for childhood leukaemia) will become reversed.
Global-NAMRIP was set up to search for such solutions and mitigations, with particular emphasis to finding alternatives to the oft-cited route of simply funding drug companies to produce more antibiotics. According to the New Scientist,:[51]
...I looked at all this and realised that even if there was a billion-dollar fund for new antibiotics, it would not sort out the problem; it might just buy us an extra decade. We need a new approach – a step change like the one antibiotics gave us when they first came in.[51]
...In many parts of the world, climate change and flooding, war, corruption, politics, received wisdom, traditions and religious practices, and the supply of fuel and money, play a far greater role in food, water, waste treatment, healthcare and the transport of microbes from one host to another, than do the outputs of the drug companies. The twin potential catastrophes are global, and so are the causes. The solutions lie with scientists and engineers to develop new technologies and embed new practices in the public and workforce; they lie with farmers, plumbers, office workers, water and sewage workers, medical practitioners, food retailers, innovators in business … indeed most of us. And they lie with those who are responsible for shaping behaviour across the world – not just the pharmaceutical companies.[50]
Global-NAMRIP creates new research teams,[67] commissions new research,[68] engaging with industry[69] to roll out solutions to society, and engaging with the public and policymakers to conduct outreach, education and dialogue.[70] The award-winning Public Engagement[70] and Policymaker Engagement[71] programmes that Leighton devised and leads have been mentioned in Parliament by the Under-Secretary of State for Health on 16 November 2017.[72][73] and Leighton has addressed the Parliamentary and Scientific Committee on his approach to addressing the threat of AMR.[74][75]
Global-NAMRIP particularly supports Low/Middle Income Countries with not-for-profit interventions,[25] for example with initiatives in urban[76] and rural Ghana (infection being the primary cause of death in rural Ghana).[77] In Uganda in 2019, Global-NAMRIP members from Uganda, Liberia, Malawi, Kenya, Ghana, Ethiopia and the UK met to compare, for the first time, the national AMR strategies of their respective countries, to share best practice. The meeting also produced significant impact in education, support for young innovators, and responded to a request from the Ugandan Minister for Health to write for him the 'Kampala Declaration on AMR'.[78]
In 2015, Leighton founded the research group Health Effects of Ultrasound in Air (HEFUA).[79][80][81] His aim was to map the increasing use of ultrasound in public places, and to investigate whether or not this increase is having adverse effects on some humans (following an investigation which revealed that the use of ultrasound in public places is increasing, and that guidelines were inadequate prior to the 2016 report).
His 2016 report[41] that first raised the issues was, in the first 2 years, downloaded over 20,000 times from the Royal Society website, leading to requests for a follow-up,[42] a journal special issue,[82][83][84][85][86][87][88] and numerous conference sessions worldwide as the importance of this topic was realised.[89][90][91] Scientists, engineers and the public around the world are now logging the location and type of device that emits ultrasound.[92][86] Leighton became an acknowledged world expert[93] on such public exposures, and on the claims of 'sonic attacks' on US Embassy staff in Cuba and China.[83][94][95][96][97][98] His expertise on the effect on humans of ultrasound in air provided the scientific basis that was cited by Giles Watling MP (Clacton, Conservative) in the Motion for leave to bring in a Bill (Standing Order No. 23) on "Anti-loitering Devices (Regulation)" (17 July 2018 Volume 645, 2.06 pm).[99][100]
In 2018, Leighton published an editorial that identified flaws in the way the statistical analysis was conducted on those identified as victims of the claimed attacks, which set up the tests in such a way that even unexposed people would, for the most part, be identified as suffering adverse health effects from the exposure.[83] In 2023, the US Office of the Director of National Intelligence (ODNI) agreed with this assessment, stating ‘that initial medical studies that led experts to believe that the AHIs [anomalous health incidents] “represented a novel medical syndrome or consistent pattern of injuries” suffered from “methodological limitations”’. Consequently, it reported that an inter-agency intelligence analysis from 7 agencies concluded that 5 considered it ‘very unlikely’ (one judging it ‘unlikely’, and one abstaining from an opinion) that a foreign adversary had deployed a weapon in the attacks.[101]
He currently serves on the Scientific Expert Group of the International Commission on Non-Ionizing Radiation Protection [102] to support appropriate protections for people (particularly children) exposed to airborne ultrasound.
Leighton's explanation of how humpback whales use sound when feeding in bubble nets is now a staple explanation on whale tour boats.[115][116][117][118] He explained how dolphins can echolocate while producing bubble nets to hunt, a process that should blind their sonar.[14][119][115]
Leighton invented systems for:
and assisted the Institute of Cancer Research with technology for tumour therapy monitoring (2010).[137]
Two billion people have been scanned in the womb under the guidelines he helped co-author for the World Federation for Ultrasound in Medicine and Biology guidelines for foetal ultrasonic scanning.[26][138]
He served on the Government of the United Kingdom's Working Group of the Advisory Committee on Dangerous Pathogens Transmissible Spongiform Encephalopathies Sub Group[139][140] and advised the Health Protection Agency[9] and the International Commission on Non-Ionizing Radiation Protection [102] on the safety of ultrasound.
Other medical and healthcare inventions and breakthroughs are listed below under Sloan Water Technology Ltd.,[15] Global-NAMRIP and HEFUA.
Leighton invented:
and, in collaboration with the National Oceanography Centre, one sold by Kongsberg[148][149][150][151] for archaeological and civil engineering purposes. Various collaborations are looking at ways of providing clean water from waste in Low- and Middle-Income Countries,[152] including mentorships of young entrepreneurs in Africa.[153]
Leighton:
In the late 1980s, Leighton[178] discovered a new ultrasonic signal[178][179][180][181] that he identified as due to surface waves on the walls of gas bubbles in liquids.[182][183][184] Multidisciplinary research in the following 11 parallel streams of work[185] turned this discovery into Sloan Water Technology Ltd:
These 11 streams of fundamental research represented the knowledge on which Sloan Water Technology Ltd. was founded.[15] Having purchased Professor Leighton’s patent suite from the University of Southampton in 2018, the Allen family chose to name the new R&D facilities ‘The Leighton Laboratories’,[211] consisting of physical science labs, mechanical engineering and electronic engineering labs, workshops, and microbiology and tissue laboratories, co-locating multiple disciplines as Professor Leighton had advocated to address unsolved problems of a societal scale (food and water security, anti-microbial resistance).[74][75] The company is currently producing technology for cleaning and changing surfaces using only cold water, air bubbles and sound (without chemicals or drugs).[212][213][33][188] This reduces the use of water and electricity,[214] reduces pollution and has run-off that is easier to convert back to drinking water, and reduces the threat of ‘superbugs’.[51][75]
Sloan Water Technology Ltd. has invented technology for cleaning surgical instruments[215][216] Food cleaning inventions have been developed for salad (which cannot be sterilized by heat treatment, and each year results in serious illness and even death from E. Coli contamination) [217][218] and hay (to reduce respiratory illness contracted through animal feed).[219] In the early days of the COVID-19 pandemic, when it was not known if the transmission route was airborne or through touch surfaces, Sloan Water Technology developed devices to clean touch surfaces.[220] Sloan Water Technology’s most significant product is aimed at reducing the suffering from chronic wounds, which cause huge suffering and costs the UK NHS over £5-billion per year.[221][222]
Leighton has been awarded the following medals and distinctions:
The citation of the 2006 Paterson Medal of the Institute of Physics states that:
Timothy Leighton's contribution is outstanding in both breadth and depth. He is an acknowledged world leader in four fields... He has delivered over 70 pioneering advances, from devices now used in hospitals to the world's first count of bubbles in the surf zone (crucial to our understanding of atmosphere-ocean gas flux, coastal erosion and the optimisation of military sonar). Behind these advances lies rigorous physics.[231]
Leighton is an Academician of three National Academies.[5] He was elected a Fellow of the Royal Society (FRS) in 2014.[245][6][246] His nomination reads:
Timothy Leighton is distinguished for his research on the acoustical physics of bubbles, especially their nonlinear behaviour; for his inventions and discoveries including bubble measurements in the surf zone, pipelines and methane seeps; for shock wave lithotripsy monitoring, disease detection in cancellous bone and needle free injection; for sonar systems that overcome bubble masking and numerous industrial applications. His seminal monograph The Acoustic Bubble has become the primary reference on bubble physical acoustics.[6]
In 2018 he was elected to Fellowship of the Academy of Medical Sciences, the citation reading for 'harnessing the physical sciences for the benefit of patients' as:
an outstanding academic inventor whose leadership in acoustical physics of bubbles has led to the development of new medical devices and procedures. His research has dominated the field of acoustic bubbles since the appearance of his monograph in 1994, ‘The Acoustic Bubble’, which was published at the age of 29. In this, he laid out the mathematical foundation upon which much of the recent cutting edge research on ultrasonic contrast agents, drug delivery, and focused ultrasound surgery has been based. He has exceptional ability to deliver engineering solutions to real world problems from conceptualisation to product development embracing an advanced practical knowledge of IP strategy.[5]
Leighton was elected a Fellow of the Royal Academy of Engineering (FREng)[8] in 2012[2] for his services to Engineering and society.[247] He was elected a Fellow of the Institute of Physics (FInstP) in 2000,[248][circular reference] Fellowship of Institute of Acoustics in 1999,[249] Fellowship of the Acoustical Society of America in 1998,[250] and Fellowship of the Cambridge Philosophical Society in 1988.[251] He is a Visiting Fellow of the Institute of Advanced Studies of Loughborough University.[252]
In 2018 the International Institute of Acoustics and Vibration (IIAV), of which he had not been a member, undertook a change to its Bylaws, and vote of all IIAV members, to create new rank of Distinguished Fellow. It is the highest rank for individual IIAV members of this international body, and Professor Leighton was the recipient in its inaugural year.[253]
Leighton has developed and conducted multiply-award-winning outreach activities to the public, and to encourage of young men and women to engage, and possibly follow careers in, science and engineering, with school visits, science fairs, exhibits, games, and appearances on TV and radio.[12][254][255] His public engagement work regarding his invention, “The most dangerous game in the world”, which he designed to communicate with the public on the issue of superbugs and how they can protect themselves and society, was mentioned by Steve Brine MP, the Under-Secretary of State for Health on 16 November 2017.[72][73] The IMDb and "Who's Who" have collated entries for Professor Leighton.[256][2] In his 2014 book 'Sonic Wonderland', the broadcaster Trevor Cox described Professor Leighton as 'a middle-aged Harry Potter'.[257]
