Cannabis tincture appeared in the United States Pharmacopoeia until 1942 (Australia 1977, UK 1970s).[3] In the 20th century cannabis lost its appeal as a medicinal product, largely due to the development of apparently suitable alternatives, such as the hypodermic needle, water-soluble analgesics and synthetic hypnotics.[4] A major concern of the regulatory authorities at that time was the widespread recreational use of cannabis.[5]
The pharmacological target for cannabis, the endocannabinoid system, has been researched since its discovery in the 1980s.
Preparation
The tincture is typically made by soaking the dried flowers of the female hemp plant (marijuana) in ethanol. The tetrahydrocannabinol (THC) and other cannabinoidsdissolve into the alcohol. Some preparations also extract some of the water-based plant products such as chlorophyll, resulting in a dark green or brown liquid. Baking or drying the cannabis to decarboxylate prior to the alcohol bath increases the amount of THC in the resulting preparation.[6][unreliable source?]
Methods of use
The tincture is ordinarily consumed orally, but may also be applied to the skin.
Gallery
Cannabis indica fluid extract, American Druggists Syndicate, pre-1937
^Giuseppe Cannazza; Cinzia Citti; Jenny Wiley; Vidhi Thakkar; Omer S.M. Hasan; Jakob Manthey; Jurgen Rehm; Astrid Otto; Charlotte Probst; Julian Sauer; Jonathon Arnold; Kevin P. Hill; Judith Spahr; Charles V. Pollack; Brock Bakewell (2018). "WHO Expert Committee on Drug – Section 1: Chemistry"(PDF). www.who.int. World Health Organization. Archived from the original(PDF) on November 12, 2020. Retrieved 19 May 2023.
