Articles to create:
Homovanillyl alcohol Dopamine receptor activation by honey bee queen pheromone. Curr Biol. 2009 Jul 28;19(14):1206-9. Epub 2009 Jun 11
Category: Vanilloids ?
PF-3845 Guanidine isothiocyanate Stearoylethanolamide [1] [2]
Names | |
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IUPAC name
2-(hexadecanoylamino)acetic acid
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Other names
N-(1-Oxohexadecyl)glycine
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Identifiers | |
3D model (JSmol)
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PubChem CID
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UNII | |
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Properties | |
C18H35NO3 | |
Molar mass | 313.4754 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Palmitoylethanolamide (PEA) is an endogenous fatty acid amide which has been demonstrated to bind toperoxisome proliferator-activated receptor alpha (PPAR-α)[3][4], GPR55 and GPR119[5]. PEA has been shown to have anit-inflammatory[4] and anti-nociceptive properties. [6]
PEA is metabolized by Fatty acid amide hydrolase (FAAH) and N-acylethanolamine-hydrolyzing acid amidase (NAAA), the latter of which has more specificity towards PEA over other fatty acid amides.[7]